|   |
2 | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | |
|
|
|
. | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
. | . | 60 | . | . | . | . | . | . | . | . | . | 70 |
Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|  |  |
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Q | T | F | Q | A | D | L | A | I | V | G | A | G | G | A | G | L | R | A | A | I | A | A | A | Q | . |
. |
. |
. |
A | N | P | N | A | K | I | A | L | I | S | K | V | Y | P | M | R | S | H | T | V | A | A | E | G | G | S | A | A | V | A | . |
. |
. |
. |
. |
. |
. |
Q | D | H | D | S | F | E | Y | H | F | H | D | T |
Query Conservation |   |
|   |   |   |   |
|
|
|
|
|
|
|
|   |
|
|
|   |
|
|   |   |
|
|   | . | . | . | . |   |
|   |   |   |   |
|   |
|
|
|
|   |   |   |   |
|
|   |
|   |   |
|   |
|
|
|   |   |   |   | . | . | . | . | . | . | . |   |   |   |
|   |   |
|   |   |   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |   |   |
|
|
|
|
|
|   |
|   |
|
|
|   |
|
|   |   |
|
|   |   |   |   |   |   |
| . | . |
|   |
|   |
|
|
|
|   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |
|   |
Template Sequence |   |
E | V | V | E | T | D | I | L | I | I | G | G | G | F | S | G | C | G | A | A | Y | E | A | A | Y | W | A | K | L | G | G | . |
. |
L | K | V | T | L | V | E | K | A | A | V | E | R | S | G | A | V | A | Q | G | L | S | A | I | N | T | Y | I | D | L | T | G | R | S | E | R | Q | N | T | L | E | D | Y | V | R | Y | V |
Template Known Secondary structure |   |
 |  |  |  |
| S |  |  |  |  |
|
| S |  |  |  |  |  |  |  |  |  |  |  |  |  |  | G | G | G | T | . | . |
|
|  |  |  |  |
| S | S |
| T | T | T |
| S | T | T | S | S |
|  |  |  |  | S |
|
|
|
| S | S | S | S | B | S |
|
|
|
|  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . |
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
2019 | 2020 | . | . | . | . | . | . | . | . | . | 2030 | . | . | . | . | . | . | . | . | . | 2040 | . | . | . | . | . | . | . | . | . | |
|
2050 | . | . | . | . | . | . | . | . | . | 2060 | . | . | . | . | . | . | . | . | . | 2070 | . | . | . | . | . | . | . | . | . | 2080 | . | . | . | . | . | . | . | . | . | 2090 | . | . | . | . | . | . |
  |
  |   |
71 | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | |
. | . |
Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| . |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
Query Sequence |   |
V | A | G | G | D | W | L | C | E | Q | D | V | V | D | Y | F | V | H | H | C | P | T | E | M | T | Q | L | E | L | W | G | C | P | W | S | R | R | P | D | G | S | V | N | V | R | R | F | G | G | M | K | I | E | R | T | W | F | A | A | D | K | T | G | F | H | M | L | H | T | L | F | Q | T | S | L | Q | F | . |
P | Q |
Query Conservation |   |
  |   |   |
|   |   |
|   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|
|   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   | . |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
Template Conservation |   |
  |   |   |   |   |
|   |   |
|   |   |
|
|   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |
|
|   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . |
|   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |
Template Sequence |   |
T | L | D | M | M | G | L | A | R | E | D | L | V | A | D | Y | A | R | H | V | D | G | T | V | H | L | F | E | K | W | G | L | P | I | W | K | T | P | D | G | K | Y | V | R | E | G | Q | W | Q | I | M | I | H | . |
. |
. |
. |
. |
. |
. |
. |
. |
G | E | S | Y | K | P | I | I | A | E | A | A | K | M | A | V | G | E |
Template Known Secondary structure |   |
 |  |  | T | T | T |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
| B |
| B |
| T | T | S |
| B |
| B | S | S | S | S |
|  |  |  |  | . | . | . | . | . | . | . | . | . |  | T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |
| G |
Template Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
2097 | . | . | 2100 | . | . | . | . | . | . | . | . | . | 2110 | . | . | . | . | . | . | . | . | . | 2120 | . | . | . | . | . | . | . | . | . | 2130 | . | . | . | . | . | . | . | . | . | 2140 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
2150 | . | . | . | . | . | . | . | . | . | 2160 | . | . | . | . | . | . | . |
  |
  |   |
150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | |
|
|
. | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | |
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |
| . | . | . |
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
I | Q | R | F | D | E | H | F | V | L | D | I | L | V | D | D | . |
. |
. |
G | H | V | R | G | L | V | A | M | N | M | M | E | G | T | L | V | Q | I | R | A | N | A | V | V | M | A | T | G | G | A | G | R | V | Y | R | . |
. |
. |
. |
. |
. |
. |
. |
. |
Y | N | T | N | G | G | I | V | T | G | D | G | M | G | M | A |
Query Conservation |   |
|   |
|   |   |   |   |   |   |   |   |
|
|   |   |   | . | . | . |   |   |   |   |
|   |
|   |   |   |   |   |   |
|   |   |   |   |
|   |
|
|
|
|
|
|
|
|
|
|   |   |   |   |   |   | . | . | . | . | . | . | . | . | . |   |   |
|   |   |   |   |   |
|
|
|
|   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |
|   |
|   |
|
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|
|
|
|
|
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |   |
|
|
Template Sequence |   |
E | N | I | Y | E | R | V | F | I | F | E | L | L | K | D | K | N | D | P | N | A | V | A | G | A | V | G | F | S | V | R | E | P | K | F | Y | V | F | K | A | K | A | V | I | L | A | T | G | G | A | T | L | L | F | R | P | R | S | T | G | E | A | A | G | R | T | W | Y | A | I | F | D | T | G | S | G | Y | Y | M | G |
Template Known Secondary structure |   |
G | G |  |  |
| S |  |  |  |  |  |  |  |  |
| T | T |
| T | T | B |  |  |  |  |  |  |  |  | S | S | S | S |
|  |  |  |  |  |
| S |  |  |  |  |
|
|
|
| B |
| S | S | S |
|
| S |
|
| S | G | G | G | G |
|
| S | S |
| T | T |
| B | S |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
2168 | . | 2170 | . | . | . | . | . | . | . | . | . | 2180 | . | . | . | . | . | . | . | . | . | 2190 | . | . | . | . | . | . | . | . | . | 2200 | . | . | . | . | . | . | . | . | . | 2210 | . | . | . | . | . | . | . | . | . | 2220 | . | . | . | . | . | . | . | . | . | 2230 | . | . | . | . | . | . | . | . | . | 2240 | . | . | . | . | . | . | . |
  |
  |   |
218 | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |
|
|
|
|  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | S | H | G | V | P | L | R | D | M | E | F | V | Q | Y | H | P | T | G | L | P | G | S | G | I | L | M | T | E | G | C | R | G | E | G | G | I | L | V | N | K | N | G | Y | R | Y | L | Q | D | Y | G | M | G | P | E | T | P | L | G | E | P | K | N | K | Y | M | E | L | G | P | R | D | K | V | S | Q | A | F | W | H |
Query Conservation |   |
  |   |
|
|
|   |
|   |   |
|
|   |   |
|   |   |
|
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |
|
|
|   |   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |
|   |   |
|
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|
|
|   |
|   |   |
|
|   | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |   |
|   |
|
|   |   |   |   |   |   |   |   |   |   | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
Template Sequence |   |
L | K | A | G | A | M | L | T | Q | F | E | H | . |
R | F | I | P | F | R | F | K | D | G | Y | G | P | V | G | A | W | F | L | F | F | K | C | K | A | K | N | A | Y | G | E | E | Y | I | K | T | R | A | A | E | L | E | K | . |
. |
. |
Y | K | P | Y | G | A | A | Q | P | I | P | T | P | L | R | N | H | Q | V | M | L |
Template Known Secondary structure |   |
 |  |  | T |
|
|  |  | S | T | T |
| . |
| B |
|
|  |  |  | T | T | T |
|
|
|
|  |  |  |  |  | T | S |
|
|
|  |  |
| T | T | S |
|
|  |  |  |  | T | S | G | G | G | T | T | . | . | . | S | T | T | G | G | G |
| S | S |
|
|  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|
|
|
|
| . |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |
|
|
|
|
|  |  |  |  | . | . | . |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
2248 | . | 2250 | . | . | . | . | . | . | . | . | . | |
2260 | . | . | . | . | . | . | . | . | . | 2270 | . | . | . | . | . | . | . | . | . | 2280 | . | . | . | . | . | . | . | . | . | 2290 | . | . | . | . | . | . | . | . | . | 2300 | . | . | |
|
|
. | . | . | . | . | . | . | 2310 | . | . | . | . | . | . | . | . | . | 2320 | . | . | . |
  |
  |   |
298 | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | |
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | |
|
|
|
|
Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |
|
|
|
|  | . | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
Query Sequence |   |
E | W | R | K | G | N | T | I | S | T | P | R | G | D | V | V | Y | L | D | L | R | H | L | G | E | K | K | L | H | E | R | L | P | F | I | C | E | L | A | K | A | Y | V | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
G | V | D | P | V | K | E | P | I | P | V | R | P | T | A | H | Y | T | M | G | G | I | . |
. |
. |
. |
. |
Query Conservation |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . |
|   |
|   |   |   |   |   |
|   |
|   |
|   |   |   |   |
|   |
|
|
| . | . | . | . | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
Template Conservation |   |
|   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |
|   |
|   |   |
|   |   |   |
|
|
|   |   |   |   |   |
Template Sequence |   |
E | I | M | D | G | N | Q | P | I | Y | M | H | T | E | E | A | L | A | E | L | A | G | G | D | K | K | K | L | K | H | I | Y | E | E | A | F | E | D | F | L | D | M | T | V | S | Q | A | L | L | W | A | C | Q | N | I | D | P | Q | E | Q | P | S | E | A | A | P | A | E | P | Y | I | M | G | S | H | S | G | E | A | G |
Template Known Secondary structure |   |
 |  |  | T | T |
|
|
|  |  |  |
|  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |  |  |  |  | T | T |
|
| T | T | T | S |
|  |  |  |  |  |
|
|
| B | B |
| S | S | S | S |
|
|
|  |
Template Predicted Secondary structure |   |
 |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|  |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
2324 | . | . | . | . | . | 2330 | . | . | . | . | . | . | . | . | . | 2340 | . | . | . | . | . | . | . | . | . | 2350 | . | . | . | . | . | . | . | . | . | 2360 | . | . | . | . | . | . | . | . | . | 2370 | . | . | . | . | . | . | . | . | . | 2380 | . | . | . | . | . | . | . | . | . | 2390 | . | . | . | . | . | . | . | . | . | 2400 | . | . | . |
  |
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
363 | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . |
Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |
|
|
|
|  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
E | T | D | Q | N | C | E | T | R | I | K | G | L | F | A | V | G | E | C | S | S | V | G | L | H | G | A | N | R | L | G | S | N | S | L | A | E | L | V | V | F | G | R | L | A | G | E | Q | A | T | E | R | A | A | T | A | G | N | G | N | E | A |
Query Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |
|
|   |   |   |   |
|   |
|
|
|
|
|
|
|
|
|   |
|   |   |   |   |
|
|
|   |
|
|
|
|   |
|
|   |   |   |   |
|   |
|   |   |
|
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |
|   |
|
|
|
|
|
|
|
|
|   |
|
|   | . | . | . |   |   |   |
|   |   |
|   | . | . | . | . |
|
|   |   |
|   |
|
|
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
F | W | V | C | G | P | E | D | L | M | P | E | E | Y | A | K | L | F | P | L | K | Y | N | R | M | T | T | V | K | G | L | F | A | I | G | D | C | A | G | A | . |
. |
. |
N | P | H | K | F | S | S | G | . |
. |
. |
. |
S | F | T | E | G | R | I | A | A | K | A | A | V | R | F | I | L | E | Q | K | P | N | P | E | I |
Template Known Secondary structure |   |
 |
|
|
|
|
| T | T | T |
|
|  |  |  |  | T | T |
| S | S |
|
| T | T | B |
| S | S | B | T |  |  |  |
| G | G | G | B |
| S | . | . | . |
|
|
|
|  |  |  |  | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
Template Predicted Secondary structure |   |
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
| . | . | . |
|
|
|
|  |  |  |  | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
2404 | . | . | . | . | . | 2410 | . | . | . | . | . | . | . | . | . | 2420 | . | . | . | . | . | . | . | . | . | 2430 | . | . | . | . | . | . | . | . | . | 2440 | . | . | . | |
|
|
. | . | . | . | . | . | 2450 | . | |
|
|
|
. | . | . | . | . | . | . | . | 2460 | . | . | . | . | . | . | . | . | . | 2470 | . | . | . | . | . | . |
  |
  |   |
425 | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | |
|
|
|
|
. | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  | . | . | . | . | . |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | I | E | A | Q | A | A | G | V | E | Q | R | L | K | D | L | V | N | Q | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
D | G | G | E | N | W | A | K | I | R | D | E | M | G | L | A | M | E | E | G | C | G | I | Y | . |
. |
. |
. |
. |
R | T | P | E | L | M | Q | K | T | I | D | K | L | A | E | L | Q | E |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |
|   |   | . | . | . | . | . |
|   |   |   |   |
|   |   |
|
|   |   |
|   |   |
|   |   |
Alig confidence |   |
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |
|
|   |   |
|   |   |
|   |   |
Template Sequence |   |
D | . |
D | A | V | V | E | E | L | K | K | K | A | Y | A | P | M | E | R | F | M | Q | Y | K | D | L | S | T | A | D | D | V | N | P | E | Y | I | L | P | W | Q | G | L | V | R | L | Q | K | I | M | D | E | Y | A | A | G | I | A | T | I | Y | K | T | N | E | K | M | L | Q | R | A | L | E | L | L | A | F | L | K | E |
Template Known Secondary structure |   |
| . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | G | G | G |
| S | S | T | T |
|
| S | S |
| B |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| G | G | G | T | T |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
| . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
2477 | |
. | . | 2480 | . | . | . | . | . | . | . | . | . | 2490 | . | . | . | . | . | . | . | . | . | 2500 | . | . | . | . | . | . | . | . | . | 2510 | . | . | . | . | . | . | . | . | . | 2520 | . | . | . | . | . | . | . | . | . | 2530 | . | . | . | . | . | . | . | . | . | 2540 | . | . | . | . | . | . | . | . | . | 2550 | . | . | . | . | . |
  |
  |   |
486 | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | |
|
. | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | |
. | . | 560 | . | . |
Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
| . | . |
|
|  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
| . |
|
|
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
Query Sequence |   |
R | F | K | R | V | R | I | T | D | T | S | S | V | F | N | T | D | L | L | Y | T | I | E | L | G | H | G | L | N | V | A | E | C | M | A | H | S | A | M | A | R | K | E | S | R | . |
. |
G | A | H | Q | R | L | D | E | G | C | T | E | R | D | D | V | N | F | L | K | H | T | L | A | F | R | D | . |
A | D | G | T | T |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |
|   |   |   |   |   |
|
|
|   |
|   |
|
|
| . | . |
|   |
|   |
|   |
|   |   |   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   | . |   |   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   | . | . | . | . | . |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |
|   |   |   |   |   |
|
|
|   |
|   |
|
|
|   |   |
|   |
|   |
|   |
| . | . |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
D | L | E | K | L | A | A | R | D | . |
. |
. |
. |
. |
L | H | E | L | M | R | A | W | E | L | V | H | R | V | W | T | A | E | A | H | V | R | H | M | L | F | R | K | E | T | R | W | P | G | Y | Y | Y | R | T | D | . |
. |
Y | P | E | L | N | D | E | E | W | K | C | F | V | C | S | K | Y | D | A | E | K | D | E | W |
Template Known Secondary structure |   |
 |  | T | T | B |
|
| S | S | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| S |
| S |
| T | T | T |
|  |  | T | T | . | . | S |
| S |
|
| T | T | T |
|
|  |  |  |  |  |  |  |  | T | T | T | T |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
| . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|  |  |  |  |
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
2556 | . | . | . | 2560 | . | . | . | . | |
|
|
|
|
. | . | . | . | . | 2570 | . | . | . | . | . | . | . | . | . | 2580 | . | . | . | . | . | . | . | . | . | 2590 | . | . | . | . | . | . | . | . | . | 2600 | . | . | . | . | |
|
. | . | . | . | . | 2610 | . | . | . | . | . | . | . | . | . | 2620 | . | . | . | . | . | . | . | . |
  |
  |   |
563 | . | . | . | . | . | . | 570 | . | |
|
|
. | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |
|
|  |  | . | . | . |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
Query Sequence |   |
R | L | E | Y | S | D | V | K | I | . |
. |
. |
T | T | L |
Query Conservation |   |
  |   |   |   |   |   |
|   |   | . | . | . |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
Template Conservation |   |
  |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
T | F | E | K | V | P | Y | V | Q | V | I | E | W | S | F |
Template Known Secondary structure |   |
 |  |  |  |  |  |
|
|
|
| S |
|
|
|
|
Template Predicted Secondary structure |   |
 |  |  |  |
|
|  |  |  |
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
2629 | 2630 | . | . | . | . | . | . | . | . | . | 2640 | . | . | . |
  |