|   |
2 | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | |
|
. | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|  |  |
|
|
|
| . | . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Q | T | F | Q | A | D | L | A | I | V | G | A | G | G | A | G | L | R | A | A | I | A | A | A | Q | A | N | P | N | A | K | I | A | L | I | S | K | V | Y | P | M | R | S | H | T | V | A | A | E | G | G | S | A | A | V | A | Q | . |
. |
D | H | D | S | F | E | Y | H | F | H | D | T | V | A | G | G | D | W | L | C | E |
Query Conservation |   |
|   |   |   |   |
|
|
|
|
|
|
|
|   |
|
|
|   |
|
|   |   |
|
|   |   |
|   |   |   |   |
|   |
|
|
|
|   |   |   |   |
|
|   |
|   |   |
|   |
|
|
|   |   |   |   |   | . | . |   |   |
|   |   |
|   |   |   |   |
|   |   |   |   |
|   |   |
|   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |
|   |
|
|
|
|
|
|
|
|   |
|
|
|   |
|
|   |   |
|
|
|   |
| . | . |   |   |
|   |
|
|
|
|   |   |   |   |
|
|   |
|   |   |
|   |
|
|
|   |
|   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |
|
Template Sequence |   |
V | D | H | E | F | D | A | V | V | V | G | A | G | G | A | G | L | R | A | A | F | G | L | S | E | A | G | . |
. |
F | N | T | A | C | V | T | K | L | F | P | T | R | S | H | T | V | A | A | Q | G | G | I | N | A | A | L | G | N | M | E | D | D | N | W | R | W | H | F | Y | D | T | V | K | G | S | D | W | L | G | D |
Template Known Secondary structure |   |
 |  |  |  |
| S |  |  |  |  |
|
| S |  |  |  |  |  |  |  |  |  |  |  |  | T | T | . | . |
|
|  |  |  |  |  | S | S |
| G | G | G | S | G | G | G | G |
|
| S |
|  |  |
|
|
|
| S | S | S |
|
|
|  |  |  |  |  |  |  |  |  |  |  | T | T | T |
| S |
|
Template Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . |
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
15 | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | |
|
. | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . |
  |
  |   |
80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | |
|
|
|
|
|
|
|
. | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Q | D | V | V | D | Y | F | V | H | H | C | P | T | E | M | T | Q | L | E | L | W | G | C | P | W | S | R | R | P | D | G | S | V | N | V | R | R | F | G | G | M | K | I | E | . |
. |
. |
. |
. |
. |
. |
. |
R | T | W | F | A | A | D | K | T | G | F | H | M | L | H | T | L | F | Q | T | S | L | Q | F | P | Q | I | Q |
Query Conservation |   |
  |   |
|
|   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|
|   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |   | . | . | . | . | . | . | . | . |
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
Template Conservation |   |
  |   |
|
|   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |
|
|   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|   |   |   |   |   |   |   | . |
|
|   |
Template Sequence |   |
Q | D | A | I | H | Y | M | T | E | Q | A | P | A | A | V | I | E | L | E | N | Y | G | M | P | F | S | R | T | E | E | G | K | I | Y | Q | R | A | F | G | G | Q | S | L | Q | F | G | K | G | G | Q | A | H | R | C | C | C | V | A | D | R | T | G | H | S | L | L | H | T | L | Y | G | R | S | L | R | Y | . |
D | T | S |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
|
| B |
| T | T | S | S | B |
|  |  |
|
| T | T |
| B | S | G | G | G | T | S |
| B |
|
|
|  |  |
| S | T | T |
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S | . |
|
|  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| . |
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
93 | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | |
. | 170 | . |
  |
  |   |
152 | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . |
Predicted Secondary structure |   |
 |  |  |
|
|  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |
|
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | F | D | E | H | F | V | L | D | I | L | V | D | D | G | H | V | R | G | L | V | A | M | N | M | M | E | G | T | L | V | Q | I | R | A | N | A | V | V | M | A | T | G | G | A | G | R | V | Y | R | Y | N | T | N | G | G | I | V | T | G | D | G | M | G | M | A | L | S | H | G | V | P | L | R | D | M | E | F | V | Q |
Query Conservation |   |
|   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |
|   |   |   |   |
|   |
|
|
|
|
|
|
|
|
|
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|
|
|
|   |   |   |
|   |   |
|
|
|   |
|   |   |
|
|   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |   |   |   |
|   |   |
|
|   |   |   |
|   |
|   |
|
|   |   |   |   |   |   |   |
|   |   |   |   |
|   |
|
|
|
|
|
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |   |
|
|   |   |
|
|
|   |
|   |   |
|
|   |   |
|
Template Sequence |   |
Y | F | V | E | Y | F | A | L | D | L | L | M | E | N | G | E | C | R | G | V | I | A | L | C | I | E | D | G | T | I | H | R | F | R | A | K | N | T | V | I | A | T | G | G | Y | G | R | T | Y | F | S | C | T | S | A | H | T | S | T | G | D | G | T | A | M | V | T | R | A | G | L | P | C | Q | D | L | E | F | V | Q |
Template Known Secondary structure |   |
 |  |  | T |  |  |  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  |  | T | T | T | T |  |  |  |  |  |  |
| S |  |  |  |  |
|
|
|
|
| G | G | G | S | S | S | B | S | S |
| T | T |
|
|
|  |  |  |  |  |  |  |  |  | T |
|
|  |  |
| T | T |
|  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
172 | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . |
  |
  |   |
232 | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . |
Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Y | H | P | T | G | L | P | G | S | G | I | L | M | T | E | G | C | R | G | E | G | G | I | L | V | N | K | N | G | Y | R | Y | L | Q | D | Y | G | M | G | P | E | T | P | L | G | E | P | K | N | K | Y | M | E | L | G | P | R | D | K | V | S | Q | A | F | W | H | E | W | R | K | G | N | T | I | S | T | P | R | G | D |
Query Conservation |   |
  |   |
|
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |
|
|
|   |   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |
|   |   |
|
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|
|   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |
|   |   |
|
|
|   |   |
|
|
|
|   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |
|   |   |
|
|   |   |   |   |
|
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |
Template Sequence |   |
F | H | P | T | G | I | Y | G | A | G | C | L | I | T | E | G | C | R | G | E | G | G | I | L | I | N | S | Q | G | E | R | F | M | E | R | Y | A | P | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
V | A | K | D | L | A | S | R | D | V | V | S | R | S | M | T | I | E | I | R | E | G | R | G | C | G | P | E | K | D | H |
Template Known Secondary structure |   |
 |  |  |  |  |  | T | T | T |
|
| B |
|
| T |  |  |  |  | T | T |
|  |  |  |
| T | T | S |
|
| T |  |  |  |  | S | T | . | . | . | . | . | . | . | . | . | . | . | T | T | G | G | G | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T |
| B | T | T | T | T |
| B |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
252 | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 |
  |
  |   |
312 | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | |
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 380 | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |
|
|
|
|  |  |  |
|
|
|
|  |  | . | . | . | . | . | . | . | . | . |
|
|
|
|  |  |  |  |  |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | V | Y | L | D | L | R | H | L | G | E | K | K | L | H | E | R | L | P | F | I | C | E | L | A | K | A | Y | V | G | V | D | P | V | K | E | P | I | P | V | R | P | T | A | H | Y | T | M | G | G | I | E | T | D | Q | N | C | E | T | . |
. |
. |
. |
. |
. |
. |
. |
. |
R | I | K | G | L | F | A | V | G | E | C | S |
Query Conservation |   |
  |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |
|   |
|   |
|   |   |   |   |
|   |
|
|
|   |
|
|   |   |   |   |
| . | . | . | . | . | . | . | . | . |   |
|
|
|
|
|
|
|
|
|   |
|
Alig confidence |   |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. |
|   |
|
|   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |
|   |   |   |   |
|   |
|   |   |   |
|
|   |
|
|
|   |
|
|   |   |   |   |
|
|   |   |   |   |   |   |   |
|   |
|
|
|
|
|
|
|
|
|   |
|
Template Sequence |   |
. |
V | Y | L | Q | L | H | H | L | P | P | Q | Q | L | A | T | R | L | P | G | I | S | E | T | A | M | I | F | A | G | V | D | V | T | K | E | P | I | P | V | L | P | T | V | H | Y | N | M | G | G | I | P | T | N | Y | K | G | Q | V | I | T | H | V | N | G | E | D | K | V | V | P | G | L | Y | A | C | G | E | A | A |
Template Known Secondary structure |   |
. |  |  |  |  |
| T | T | S |
|  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |
|
|
| T | T | T | S |
|  |  |  |  |  |  |  |  |  |  | S |
| B |  |  | B |
| T | T | S |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  |  |  |
| G | G | G |  |
Template Predicted Secondary structure |   |
. |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |
|
|  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
321 | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . |
  |
  |   |
383 | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
S | V | G | L | H | G | A | N | R | L | G | S | N | S | L | A | E | L | V | V | F | G | R | L | A | G | E | Q | A | T | E | R | A | A | T | A | G | N | G | N | E | A | A | I | E | A | Q | A | A | G | V | E | Q | R | L | K | D | L | V | N | Q | D | G | G | E | N | W | A | K | I | R | D | E | M | G | L | A | M | E | E |
Query Conservation |   |
  |   |   |   |
|
|
|   |
|
|
|
|   |
|
|   |   |   |   |
|   |
|   |   |
|
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |
|
|
|
|
|
|
|
|   |
|
|   |   |   |   |
|   |
|   |   |
|
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
Template Sequence |   |
S | A | S | V | H | G | A | N | R | L | G | A | N | S | L | L | D | L | V | V | F | G | R | A | C | A | L | T | I | A | E | T | C | K | P | G | E | P | V | P | S | I | K | . |
P | N | A | G | E | E | S | V | A | N | L | D | K | L | R | F | A | D | G | T | I | R | T | S | E | A | R | L | N | M | Q | K | T | M | Q | S |
Template Known Secondary structure |   |
 |
| S | S | S | T | T | S |
|
| T | T | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| T | T |
|
|
|
|
|
|
| . | T | T | T | T |  |  |  |  |  |  |  |  |  |  |  |  |
| B | S | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
| . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | |
. | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . |
  |
  |   |
463 | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | C | G | I | Y | R | T | P | E | L | M | Q | K | T | I | D | K | L | A | E | L | Q | E | R | F | K | R | V | R | I | T | D | T | S | S | V | F | N | T | D | L | L | Y | T | I | E | L | G | H | G | L | N | V | A | E | C | M | A | H | S | A | M | A | R | K | E | S | R | G | A | H | Q | R | L | D | E | G | C | T | E |
Query Conservation |   |
  |   |
|   |   |
|   |   |   |   |
|   |   |
|
|   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |
|   |   |   |   |   |
|
|
|   |
|   |
|
|
|
|   |
|   |
|   |
|   |   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
Template Conservation |   |
  |   |
|
|   |
|   |   |   |   |
|   |   |
|
|   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |   |
|   |   |
|   |   |   |   |   |   |
|
|   |
|   |
|
|
|
|   |
|   |
|   |
| . | . |
|
|   |
Template Sequence |   |
H | A | A | V | F | R | T | G | S | I | L | Q | E | G | C | E | K | L | S | Q | I | Y | R | D | L | A | H | L | K | T | F | D | R | G | I | V | W | N | T | D | L | V | E | T | L | E | L | Q | N | L | M | L | C | A | L | Q | T | I | Y | G | A | E | A | R | K | E | S | R | G | A | H | A | R | E | D | . |
. |
Y | K | L |
Template Known Secondary structure |   |
 | S | S | S |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | G | G | G | G |  |  |
|
|
|
|
| S | T | T |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| S |
| B | T | T | B |  |  | T | T | . | . | B |
| S |
Template Predicted Secondary structure |   |
|
|
|  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |
|
|
| . | . |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
479 | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | |
|
. | . | . |
  |
  |   |
543 | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | 550 | . | . | . | . | . | . | . | . | . | |
560 | . | . | . | . | . | . | . | . | . | 570 | |
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 580 | . |
Predicted Secondary structure |   |
|
|  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |
|
|
| . |
|
|  |  |  |  |  |  |
|
|  | . | . | . | . | . | . | . | . |  |  |  |  |
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | D | D | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
V | N | F | L | K | H | T | L | A | F | R | D | A | D | . |
G | T | T | R | L | E | Y | S | D | V | K | . |
. |
. |
. |
. |
. |
. |
. |
I | T | T | L | P | P | A | K | R | V | Y |
Query Conservation |   |
  |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . |
|   |   |   |   |   |   |   |   |
|   | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |
|   |
|
Alig confidence |   |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |
|
Template Sequence |   |
R | I | D | E | F | D | Y | S | K | P | L | Q | G | Q | Q | K | R | P | F | E | E | H | W | R | K | H | T | L | S | Y | V | D | V | K | S | G | K | V | T | L | K | Y | R | P | V | I | D | R | T | L | N | E | E | D | C | S | S | V | P | P | A | I | R | S | Y |
Template Known Secondary structure |   |
|
|
| S | S |
| T | T | S |
|
| T | T |
|
|
|
|
| G | G | G | S |
|
|  |  |  |  |  |  |  |  | T | T | T | T |  |  |  |  |  |  |  |  |
|
|
|
|
| S |
| T | T | T | S |
|
|
|
|
|
|
|
|
|
|
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
557 | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . | . | . | . | . | 620 | . |
  |