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Job DescriptionP00363
Confidence99.67%DateThu Jan 5 10:56:34 GMT 2012
Rank85Aligned Residues234
% Identity25%Templatec1gthD_
PDB info PDB header:oxidoreductaseChain: D: PDB Molecule:dihydropyrimidine dehydrogenase; PDBTitle: dihydropyrimidine dehydrogenase (dpd) from pig, ternary2 complex with nadph and 5-iodouracil
Resolution2.25 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   7..10.........20.........30.. .......40.........50.........60.........70.........80.....
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Query Sequence  DLAIVGAGGAGLRAAIAAAQANPNAK. IALISKVYPMRSHTVAAEGGSAAVAQDHDSFEYHFHDTVAGGDWLCEQDVVDY
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Template Sequence  KIALLGAGPASISCASFLARLG. . YSDITIFEKQEYVGGLSTS. . . EIPQFRLPYD. . . . . . . . . . . . . . . . . . . . . . . .
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   189190.........200.........210 .........220......... 230.........
 
   86...90.........100.........110.. ......
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Query Sequence  FVHHCPTEMTQLELWGCPWSRRPDGSV. NVRRFG. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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Template Sequence  . . . VVNFEIELMKDLGVKIICGKSLSENEITLNTLKEEGYKAAFIGIGLPEPKTDDIFQGLTQDQGFYTSKDFLPLVAKS
Template Known Secondary structure  ...TTT
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BSTTSB
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GGGTT

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   240.........250.........260.........270.........280.........290.........300.........310......
 
   119120.........130.........140.........150.........160
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . GMKIERTWFAADKTGFHMLHTLFQTSLQFPQIQRFDEHFVLD
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Template Sequence  SKAGMCACHSPLPSIRGAVIVLGAGDTAFDCATSALRCGARRVFLVFRKGFVNIRAVPEEVELAKEE. KCEFLPFLSPRK
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   317..320.........330.........340.........350.........360.........370.........380... ......390.....
 
   161........170....... ..180.........190.........200.........210.........220.........230
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Query Sequence  ILVDDGHVRGLVAMNMM. . . . . . . . . . EGTLVQIRANAVVMATGGAGRVYRYNTNGGIVTGDGMGMALSHGVPLRDMEFV
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Template Sequence  VIVKGGRIVAVQFVRTEQDETGKWNEDEDQIVHLKADVVISAFGSVLRD. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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   396...400.........410.........420.........430.........440....
 
   231........240.........250.........260.........270.........280.........290.........300.........310
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Query Sequence  QYHPTGLPGSGILMTEGCRGEGGILVNKNGYRYLQDYGMGPETPLGEPKNKYMELGPRDKVSQAFWHEWRKGNTISTPRG
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   311........320.........330.........340.........350.........360..... ....370.........380.........
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Query Sequence  DVVYLDLRHLGEKKLHERLPFICELAKAYVGVDPVKEPIPVRPTAHYTMGGIETD. QNCETRIKGLFAVGECSSVGLHGA
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Template Sequence  . . . . . . . . . . . . . . . . . . . . . . PKVKEALSPIKFNRW. . . . . . . . . . . . DLPEVDPETMQTSEPWVFAGGDIVG. . . . . .
Template Known Secondary structure  ......................TTTTS
B
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   445....450......... 460.........470.........480....
 
   390.........400.........410.........420.......
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Query Sequence  NRLGSNSLAELVVFGRLAGEQATERAATAGNGNEAAIE
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Template Sequence  . . . MANTTVESVNDGKQASWYIHKYIQAQYGASVSAKP
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   485....490.........500.........510.........
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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