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Job DescriptionP77148
Confidence99.58%DateThu Jan 5 12:25:39 GMT 2012
Rank19Aligned Residues283
% Identity23%Templatec1gthD_
PDB info PDB header:oxidoreductaseChain: D: PDB Molecule:dihydropyrimidine dehydrogenase; PDBTitle: dihydropyrimidine dehydrogenase (dpd) from pig, ternary2 complex with nadph and 5-iodouracil
Resolution2.25 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   2.......10.........20........ .30.........40.........50.........60.........70.........80
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Query Sequence  KKIAIVGAGPTGIYTLFSLLQQQTPLS. ISIFEQADEAGVGMPYSDEENSKMMLANIASIEIPPIYCTYLEWLQKQEDSH
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Template Sequence  AKIALLGAGPASISCASFLARL. . GYSDITIFEKQEYVGGLSTS. . EIPQFRLP. . . . . . . . . . . . . . . . . . . . . . . . . .
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   188.190.........200......... 210.........220......... 230.......
 
   81........90.........100.........110.........120.........130.........140.........150.........160
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Query Sequence  LQRYGVKKETLHDRQFLPRILLGEYFRDQFLRLVDQARQQKFAVAVYESCQVTDLQITNAGVMLATNQDLPSETFDLAVI
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Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . YDVVNFEIELMKDLG. . VKIICGKSL. . . . . . . . SENEITLNTLKEEGYKAAFI
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   238.240.........250.. .......260. ........270.........280.
 
   161........170.........180......... 190.........200.........210.........220
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Query Sequence  ATGHVWPDEEEATRTYFPSPWSGLMEAKV. . . . . . . . . . . . . . . . . . . . DACNVGIMGTSLSGLDAAMAVAIQHGSFIED
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Template Sequence  GIGLPEPKTDDIFQGLTQDQGFYTSKDFLPLVAKSSKAGMCACHSPLPSIRGAVIVLGAGDTAFDCATSALRCGAR. . . .
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GGGTT

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   282.......290.........300.........310.........320.........330.........340.........350.......
 
   221........230.........240.........250.........260.........270.........280.........290.........300
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Query Sequence  DKQHVVFHRDNASEKLNITLLSRTGILPEADFYCPIPYEPLHIVTDQALNAEIQKGEEGLLDRVFRLIVEEIKFADPDWS
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Template Sequence  . . . . . . . . . . . . . . . . RVFLVFRKGF. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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SS
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   358.360.......
 
   301........310.........320.........330.........340.........350.........360.........370.........380
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Query Sequence  QRIALESLNVDSFAQAWFAERKQRDPFDWAEKNLQEVERNKREKHTVPWRYVILRLHEAVQEIVPHLNEHDHKRFSKGLA
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   381........390.........400.........410.........420...... ...430.........440...
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Query Sequence  RVFIDNYAAIPSESIRRLLALREAGIIHILALGEDYKMEINESRTV. . . . . . . . . . . . . . . . . LKTEDNSYSFDVFIDAR
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Template Sequence  . . . . . . . . VNIRAVPEEVELAKEEK. CEFLPFLSPRKVIVKGGRIVAVQFVRTEQDETGKWNEDEDQIVHLKADVVISAF
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   368.370.........380.... .....390.........400.........410.........420.........430........
 
   444.....450.........460.........470 .........480.........490.........500.........510.........520.
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Query Sequence  GQRPLKVKDIPFPGLREQLQKTGDEIP. . DVGEDYTLQQPEDIRGRVAFGALPWLMHDQPFVQGLTACAEIGEAMARAVV
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Template Sequence  GSVL. . RDPKV. . . KEALSPIKFNRWDLPEVDPETMQTSEPW. . . . . VFAGGDIVGMANTTVESVNDGKQASWYIHKYIQ
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...TTTTS
B
TTSSB


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GGGGT


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   439440.. ..... ..450.........460.........470..... ....480.........490.........500........
 
   522.
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Query Sequence  KP
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Template Sequence  AQ
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Template SS confidence 

   509510
 
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Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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