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Job DescriptionP77148
Confidence99.12%DateThu Jan 5 12:25:39 GMT 2012
Rank107Aligned Residues323
% Identity15%Templatec1bwcA_
PDB info PDB header:oxidoreductaseChain: A: PDB Molecule:protein (glutathione reductase); PDBTitle: structure of human glutathione reductase complexed with ajoene2 inhibitor and subversive substrate
Resolution2.10 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


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Query Sequence  MKK. . IAIVGAGPTGIYTLFSLLQQQTPLSISIFEQADEAGVGMPYSDEENSKMMLANIASIEIPPIYCTYLEWLQKQED
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Template Sequence  VASYDYLVIGGGSGGLASARRAAEL. . GARAAVVESHK. LGGTCVNVGC. . . . . . . . . . . . . . . . . . . VPKKVMWNTAVH
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   18.20.........30.........40.. .......50... ......60... ......70.....
 
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Query Sequence  SHLQRYGVKKETLHDRQFLPRILLGEYFRDQFLRLVDQARQQKFAVAVYESCQVTDLQITNAGVMLATNQDLPSETFDLA
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Template Sequence  SEFMHDHADYGFPSCEGKFNWRVIKEKRDAYVSRLNAIYQNNLTKSHIEIIRGHAAFTSDPKP. . . TIEVSGKKYTAPHI
Template Known Secondary structure  TGGGTS







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   76...80.........90.........100.........110.........120.........130........ .140.........150..
 
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Query Sequence  VIATG. . HVWPDEEEATRTYFPSPWSGLMEAKVDACNVGIMGTSLSGLDAAMAVAIQHGSFIEDDKQHVVFHRDNASEKL
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Template Sequence  LIATGGMPSTPHESQIPGASLGITSDGFFQLEELPGRSVIVGAGYIAVEMAGILSA. . . . . . . . . . . . . . . . . . . . . LGS
Template Known Secondary structure 






TTTSTTGGGSB
TT

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   153......160.........170.........180.........190.........200........ .210.
 
   237..240.........250.........260.........270.........280.........290.........300.........310......
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Query Sequence  NITLLSRTGILPEADFYCPIPYEPLHIVTDQALNAEIQKGEEGLLDRVFRLIVEEIKFADPDWSQRIALESLNVDSFAQA
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Template Sequence  KTSLMIRHDKVLR. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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SSSSS
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   212.......220....
 
   317..320.........330.........340.........350.........360.........370.........380.........390......
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Query Sequence  WFAERKQRDPFDWAEKNLQEVERNKREKHTVPWRYVILRLHEAVQEIVPHLNEHDHKRFSKGLARVFIDNYAAIPSESIR
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Template Conservation  ........................................................................        
Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . SFDSMIST
Template Known Secondary structure  ........................................................................TS
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   397..400.........410.........420.........430.. .......440.........450.........460......
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Query Sequence  RLLALREAGIIHILALGEDYKMEINESRTVLKTEDN. . . . . . . . . . SYSFDVFIDARGQRPLKVKDIPFPGLREQLQKTG
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Template Sequence  NCTEELENAGVEVLKFSQVKEVKKTLSGLEVSMVTAVPGRLPVMTMIPDVDCLLWAIGRVP. . NTKDL. . . SLNKLGIQT
Template Known Secondary structure  TT
TTTT

TTS

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GGGTT

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   233......240.........250.........260.........270.........280.........290... ..... .300.......
 
   467..470.........480.........490.........500.........510.........520.
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Query Sequence  DEIPDVGEDYTLQQPEDIRGRVAFGALPWLMHDQPFVQGLTACAEIGEAMARAVV
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Template Sequence  DDKGHIIVDEFQN. . TNVKGIYAV. . . . GDVCGKALLT. . PVAIAAGRKLAHRLF
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TT

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   308.310.........320 ......... 330......... 340.........350....
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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