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Job DescriptionP46859
Confidence98.67%DateThu Jan 5 12:04:31 GMT 2012
Rank137Aligned Residues163
% Identity14%Templatec1qhiA_
PDB info PDB header:transferaseChain: A: PDB Molecule:protein (thymidine kinase); PDBTitle: herpes simplex virus type-i thymidine kinase complexed with2 a novel non-substrate inhibitor, 9-(4-hydroxybutyl)-n2-3 phenylguanine
Resolution1.90 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   11........20.........30........ .40.........50.........60.........70........
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Query Sequence  YVLMGVSGSGKSAVASEVAHQLHAAFLD. . . . . . GDFLHPRRNIEKMASGEPLNDDDRKPWLQALNDAAFAMQR. . . . . .
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Template Sequence  VYIDGPHGMGKTTTTQLLDIVYVPEPMTYWRVLGASETIANIYTTQHRLDQGEISAGDAAVVMTSAQITMGMPYAVTDAV
Template Known Secondary structure 
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   52.......60.........70.........80.........90.........100.........110.........120.........130.
 
   7980.........90. ........100.........110.........120..... .
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Query Sequence  . . . . . . . . . . TNKVSLIVCSALK. . . . . . . . . . . . . . . . . . . . KHYRDLLREGNPNLSFIYLKGDFDVIESRLKARK. . G
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Template Sequence  LAPHIGGEAPPALTLIFDRHPIAALLCYPAARYLMGSMTPQAVLAFVALIPPTLPGTNIVLGALPEDRHIDRLAKRQRPG
Template Known Secondary structure  GGG


S

TTTTSS
T




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TT
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   139140.........150.........160.........170.........180.........190.........200.........210........
 
   127..130.........140.... ...
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Query Sequence  HFFKTQMLVTQFETLQEP. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . GAD
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Template Sequence  ERLDLAMLAAIRRVYGLLANTVRYLQCGGSWREDWGQLSPRPHIGDTLFTLFRAPELLAPNGDLYNVFAWALDVLAKRLR
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TT

GGGG




GGGSGGGGG

GGGB
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B
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   225....230.........240.........250.........260.........270.........280.........290.........300....
 
   148.150.........160.........170...
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Query Sequence  ETDVLVVDIDQPLEGVVASTIEVIKK
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Template Sequence  SMHVFILDYDQSPAGCRDALLQLTSG
Template Known Secondary structure  T

SS
GGG
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   321........330.........340......
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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