|   |
7 | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
W | W | Q | N | G | V | I | Y | Q | I | Y | P | K | S | F | Q | D | T | T | G | S | G | T | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
G | D | L | R | G | V | I | Q | H | L | D | Y | L | H | K | L | G | V | D | A | I | W | L | T | P | F | Y | V | S | P | Q | V | D | N | G | Y |
Query Conservation |   |
|   |   |   |   |
|
|
|   |
|   |   |   |   |
|   |
|   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|   |   |
|
|   |   |   |
|
|
|
|
|   |
|
|
|   |   |
|   |
|   |
|
|   |   |   |   |   |   |   |   |
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
Template Conservation |   |
|   |   |   |   |
|   |
|   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|
|   |   |   |
|
|
|
|   |   |
|
|   |   |   |
|   |
|   |
|
|   |   |   |   |   |   | . |   |
|
|
Template Sequence |   |
W | Y | E | G | A | F | F | Y | Q | I | F | P | D | R | F | F | R | A | G | P | P | G | R | P | A | P | A | G | P | F | E | P | W | E | A | P | P | T | L | R | G | F | K | G | G | T | L | W | G | V | A | E | K | L | P | Y | L | L | D | L | G | V | E | A | I | Y | L | N | P | V | F | A | S | T | A | N | . |
H | R | Y |
Template Known Secondary structure |   |
T | T | S | S |
|
|  |  |  |  |
| G | G | G | S |
|
|
| S |
|
|
| S | S |
|
|
| S |
|
|
|
| T | T | S |
|
|
| S | S |
|
|
|
|
|
|  |  |  |  |  |  | T |  |  |  |  |  |  |  | T |
|
|  |  |  |  |
|
|
|  |  |  | S | S | T | . | T |
|
|
Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
| . |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
3 | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | |
. | 80 | . |
  |
  |   |
66 | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | |
|
. | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
| . | . |
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
D | V | A | N | Y | T | A | I | D | P | T | Y | G | T | L | D | D | F | D | E | L | V | T | Q | A | K | S | R | G | I | R | I | I | L | D | M | V | F | N | H | T | S | T | Q | H | A | W | F | R | E | A | L | . |
. |
N | K | E | S | P | Y | R | Q | F | Y | I | W | R | D | G | E | P | E | T | P | P | N | N | W | R | S |
Query Conservation |   |
  |   |   |
|   |   |   |
|
|   |   |   |
|
|   |   |
|
|
|   |
|
|   |   |   |
|   |   |
|
|   |
|
|
|
|   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |   |   |
|   |   |   |
|
|   |   |
|
|
|   |   |
|   |
|   |
|
|   |   |
|
|   |   |
|
|   |
|
|
|
|   |
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . |
Template Sequence |   |
H | T | V | D | Y | F | Q | V | D | P | I | L | G | G | N | E | A | L | R | H | L | L | E | V | A | H | A | H | G | V | R | V | I | L | D | G | V | F | N | H | T | G | R | G | F | F | A | F | Q | H | L | X | E | N | G | E | Q | S | P | Y | R | D | W | Y | H | V | K | G | F | P | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
S |  |  |  |  |  |  |  |
| G | G | G | T |
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |  |
|
| S | B |
|
| T | T | S |  |  |  |  |  |  |  |  |  | G | G | G |
| T | T | G | G | G | B |
| B |
| S | S | S |
| . | . | . | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
82 | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | |
|
|
|
|
|
|
|
|
  |
  |   |
144 | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
K | F | G | G | S | A | W | R | W | H | A | E | S | E | Q | Y | Y | L | H | L | F | A | P | E | Q | A | D | L | N | W | E | N | P | A | V | R | A | E | L | K | K | V | C | E | F | W | A | D | R | G | V | D | G | L | R | L | D | V | V | N | L | I | S | K | D | P | R | F | P | E | D | L | D | G | D | G | R | R | F | Y |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|
|
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
. | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
. | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |
|   |   |   |
|
|
|
|
|
|   |
|   |   |   |   |
|   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
K | A | Y | T | A | H | P | N | Y | E | A | W | W | G | N | P | E | L | P | K | L | K | V | E | T | P | A | V | R | E | Y | L | L | A | V | A | E | H | W | I | R | F | G | V | D | G | W | R | L | D | V | P | N | E | I | P | D | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
. | . | . | . | . | . | . |
| T | T | S | S | S |
| S | B |
| B | G | G | G |
| T | T | S | B | B | B |
| T | T | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
|  |  |  |  | S | S | G | G | G |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
. | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|  |  |  |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
|
153 | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |
  |   |
224 | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | |
. | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | |
|
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| . |
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | D | G | P | R | A | H | E | F | L | H | E | M | N | R | D | V | F | T | . |
P | R | G | L | M | T | V | G | E | M | S | S | T | S | L | E | H | C | Q | R | Y | A | A | L | T | G | S | E | . |
. |
. |
. |
. |
. |
. |
L | S | M | T | F | N | F | H | H | L | K | V | D | Y | P | G | G | E | K | W | T | L | A | K | P |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
. | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
. |
. |
. |
. |
. |
. |
P | T | F | W | R | E | F | R | Q | R | V | K | G | A | N | P | E | A | Y | I | V | G | E | I | W | E | E | A | D | F | W | L | Q | G | D | X | F | D | A | V | X | N | Y | P | L | A | R | A | V | L | G | F | V | G | G | E | A | L | D | R | D | L | A | A | Q | T | G | L | G | R | I | E | P | L |
Template Known Secondary structure |   |
. | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| T | T |
|  |  |  |  |
|
| S | S |
|
| S | G | G | G | S | S | S | S |
| S |  |  | B |
|  |  |  |  |  |  |  |  |  |  |  |  | G | G | G | S |
|  |  |  |  | T | T | S | T | T |
| S |
|
|
|
|
Template Predicted Secondary structure |   |
. | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . |
  |
  |   |
296 | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | |
|
. | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
| . | . |
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |
|
|  |  |  |  |
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
D | F | V | A | L | K | T | L | F | R | H | W | Q | Q | G | M | H | N | V | . |
. |
A | W | N | A | L | F | W | C | N | H | D | Q | P | R | I | V | S | R | F | G | D | E | G | E | Y | R | V | P | A | A | K | M | L | A | M | V | L | H | G | M | Q | G | T | P | Y | I | Y | Q | G | E | E | I | G | M | T | N | P | H | F |
Query Conservation |   |
  |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|
|   |
|   |
|   |
|   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |
|
|   |
|   |
|   |
|   |   |   |   |   |   |
Template Sequence |   |
Q | A | L | A | F | S | H | R | L | E | D | L | F | G | R | Y | R | P | E | V | V | R | A | Q | X | N | L | L | T | S | H | D | T | P | R | L | L | S | L | X | R | G | . |
. |
. |
. |
S | V | E | R | A | R | L | A | L | A | L | L | F | L | L | P | G | N | P | T | V | Y | Y | G | E | E | V | G | X | A | G | G | K | D |
Template Known Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  | T | T | S | S |
|  |  |  |  | T | T |
|  |  |
| S |
|
| T | T | S |
|
|  |  |  |  | T | T | T | . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  | T | T | S | S | S |  |  |  |  |  | T | T | G | G | G | T |
|
|
|
| S | T |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
284 | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | |
|
|
|
. | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . |
  |
  |   |
374 | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . |
Predicted Secondary structure |   |
|
|
|  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | R | I | T | D | Y | R | D | V | E | S | L | N | M | F | A | E | L | R | N | D | G | R | D | A | D | E | L | L | A | I | L | A | S | K | S | R | D | N | S | R | T | P | M | Q | W | S | N | G | D | N | A | G | F | T | A | G | E | P | W | I | G | L | G | D | N | Y | Q | Q | I | N | V | E | A | A | L | A | D | D | S |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
Alig confidence |   |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
Template Conservation |   |
  |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |
|   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |
Template Sequence |   |
P | E | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
N | R | G | G | X | V | W | E | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
E | A | R | W | Q | K |
Template Known Secondary structure |   |
T | T | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | T |
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | G | G | G | S |
|  |
Template Predicted Secondary structure |   |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
360 | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
370 | . | . | . | . | . |
  |
  |   |
454 | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | |
|
|
|
|
. | 520 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
| . | . | . | . | . |
|
|  |  |  |  |  |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
S | V | F | Y | T | Y | Q | K | L | I | A | L | R | K | Q | E | A | I | L | T | W | G | N | Y | Q | D | L | L | P | N | S | P | V | L | W | C | Y | R | R | E | W | K | G | Q | T | L | L | V | I | A | N | L | S | R | E | I | Q | P | W | Q | A | G | Q | M | R | . |
. |
. |
. |
. |
G | N | W | Q | L | V | M | H | N | Y |
Query Conservation |   |
  |   |   |   |   |   |   |   |
|   |   |
|
|   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |
|   |   |   |   |   |   |   |
|
|
|   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |   | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |
|   |   |
|
|   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   | . |   |
|   |
|
|   |
| . | . | . | . |   |   |   |
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |
Template Sequence |   |
D | L | R | E | T | V | K | R | L | A | R | L | R | K | E | H | P | A | L | R | T | A | P | Y | L | R | I | Y | A | Q | D | . |
G | H | L | A | F | A | R | . |
. |
. |
. |
G | P | Y | L | A | V | V | N | A | S | P | H | P | F | R | Q | D | F | P | L | H | G | V | F | P | R | G | G | R | A | V | D | L | L | S | G | E |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| T |  |  |  |  | S |
|
|  |  |  |  |  |  | T | . | T |  |  |  |  |  |  | . | . | . | . | T | T |  |  |  |  |  |  |
| S | S | S |
|  |  |
|
| S | B |
| T | T | S |
| T | T |
|
|
|  |  |  | T | T | T |
|
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |
|
|
|  |  |  |  |  |
|
|
| . |
|  |  |  |  |  |  | . | . | . | . |
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
376 | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | |
. | . | . | 410 | . | . | . | |
|
|
|
. | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 |
  |
  |   |
529 | 530 | . | . | . | . | . | |
|
. | . | . | . | 540 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
| . | . |
|  |  |  |  |
|
|
|  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | E | A | S | P | Q | P | . |
. |
C | A | M | N | L | R | P | F | E | A | V | W | W |
Query Conservation |   |
  |   |   |   |   |   |   | . | . |   |   |   |   |
|   |
|   |   |   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |
|   |   |   |   |   |   |
|   |
|   |   |   |   |
|   |
Template Sequence |   |
V | C | T | P | Q | G | G | R | L | C | G | P | V | L | P | P | F | S | L | A | L | W |
Template Known Secondary structure |   |
 |  |
|
| B | T | T | B |
|
|
|
|  |  |
| T | T |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
451 | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . |
  |