|   |
23 | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | |
|
. | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | |
|
|
80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | |
|
Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  | . | . |  |  |
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
| . | . | . |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
| . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
Query Sequence |   |
E | S | S | P | E | A | L | R | I | G | Y | Q | K | G | S | I | G | M | V | L | A | . |
. |
K | S | H | Q | L | L | E | K | R | Y | P | E | S | K | I | S | W | V | E | F | P | A | G | P | Q | M | L | E | A | L | N | V | G | S | I | D | . |
. |
. |
L | G | S | T | G | D | I | P | P | I | F | A | Q | A | A | G | . |
. |
Query Conservation |   |
  |   |   |   |   |   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |
| . | . |   |   |   |
|   |   |   |   |   |   |   |
|
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |   |
| . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| . | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
Template Conservation |   |
|   |
|   |
|   |
|
|
|
|   |   |
|
|
|
|   |
|   |   |
|
|   |   |
|   |   |
|   |
|   |   |
|   |   |
|
|
|   |
|   |
|
|   |
|
|   |   |
|   |   |   |   |   |   |
|   |   |
|
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
P | E | R | P | V | N | X | V | V | P | F | A | A | G | G | P | T | D | N | V | A | R | S | L | A | E | S | X | R | P | T | L | G | E | T | V | V | V | E | N | K | G | G | A | G | G | T | I | G | T | T | Q | V | A | R | A | Q | P | D | G | Y | S | I | L | L | X | H | A | G | F | S | T | A | P | S | L | Y | K | N | P |
Template Known Secondary structure |   |
| S | S |
|  |  |  |  |  | S | S |
| T | T | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S | S |
|  |  |  |  |  |
|
|
| G | G | G |  |  |  |  |  |  |  |  | T | S |
| S | S | S | S |  |  |  |  |  |  | T |  |  |  |  | G | G | G | T |
| S |
|
|
Template Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
3 | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . |
  |
  |   |
|
|
|
|
|
96 | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
. | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . |
Predicted Secondary structure |   |
. | . | . | . | . |
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |
Query SS confidence |   |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
A | D | L | V | Y | V | G | V | E | P | P | K | P | K | A | E | V | I | L | V | A | E | N | S | P | I | K | T | V | A | D | L | . |
. |
. |
. |
. |
. |
. |
. |
K | G | H | K | V | A | F | Q | K | G | S | S | S | H | N | L | L | L | R | A | L | R | Q | A | G | L | K | F | T | D | I | Q | P | T | Y |
Query Conservation |   |
. | . | . | . | . |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |   |
|   |
|   |   |   |   |
|
| . | . | . | . | . | . | . | . |
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
Alig confidence |   |
. | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
Template Conservation |   |
  |   |   |   |   |   |
|
|   |
|
|   |   |   |   |   |   | . | . |   |   |   |
|   |
|   |   |
|
|
|   |   |
|   |   |   |
|
|   |   |
|
|   |   |
|   |   |
|   |   |
|   |   |
|   |
|
|   |   |   |
|   |   |   |   |
|   |   |   |   |
|   |   |   |   |   |
|   | . |
|
Template Sequence |   |
G | Y | E | P | Y | T | S | F | E | P | I | G | L | V | V | D | V | . |
. |
P | X | T | I | I | A | R | G | D | F | P | P | N | N | I | K | E | L | A | E | Y | V | K | K | N | A | D | K | I | S | L | A | N | A | G | I | G | A | A | S | H | L | C | G | T | X | L | V | E | A | L | G | V | N | L | L | T | I | P | . |
Y |
Template Known Secondary structure |   |
S | S |
| T | T | T | S |  |  |  |  |  |  |  |  |  |  | . | . |  |  |  |  |  |  |  | T | T |
| S |
|
| S |  |  |  |  |  |  |  |  |  |  |  | G | G | G |
|  |  |  |  | S |
| T | T | S |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
|
|  |  |  |  | . |
|
Template Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
| . | . |
|  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
| . |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
83 | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | |
|
100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | |
. |
  |
  |   |
163 | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . |
Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | T | P | A | D | A | R | A | A | F | Q | Q | G | N | V | D | A | W | A | I | W | D | P | Y | Y | S | A | A | L | L | Q | G | G | V | R | V | L | K | D | G | T | D | L | N | Q | T | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
G | S | F | Y | L | A | A | R | P | Y | A | E | K | N |
Query Conservation |   |
  |   |   |   |   |   |   |   |
|
|   |   |
|   |
|
|
|   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
| . | . | . |
|
Template Conservation |   |
  |
|   |   |   |   |   |   |
|
|
|   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |
|
|   |
|
|   |   |   |   |
|
|   |   |   |   |
|
|
|
|
|   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |
|
| . | . | . |
|
Template Sequence |   |
K | G | T | A | P | A | X | N | D | L | L | G | K | Q | V | D | L | X | C | D | Q | T | T | N | T | T | Q | Q | I | T | S | G | K | V | K | A | Y | A | V | T | S | L | K | R | V | P | T | L | P | D | L | P | T | X | D | E | S | G | Y | K | G | F | E | V | G | I | W | H | G | X | W | A | P | K | G | T | . |
. |
. |
P |
Template Known Secondary structure |   |
S | S |  |  |  |  |  |  |  |  |  | T | T | S | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | S |  |  |  |  |  |  |
| S | S | S |
|
| T | T | S | T | T | S |
| B | T | T | T | T | T |
| T | T |
|
|
|  |  |  |  |  |  |  |  |  | T | T |
| . | . | . |
|
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
| . | . | . |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | |
|
|
. |
  |
  |   |
223 | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | |
|
|
|
|
|
. | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | A | F | I | Q | G | V | L | A | T | F | S | E | A | D | A | L | T | R | S | Q | R | E | Q | S | I | A | L | L | A | K | T | . |
. |
. |
. |
. |
. |
M | G | L | P | A | P | V | I | A | S | Y | L | D | H | R | P | P | T | T | I | K | P | V | N | A | E | V | A | A | L | Q | Q | Q | T | A | D | L | F | Y | E | N | R |
Query Conservation |   |
|
|   |
|   |   |
|   |   |
|   |   |   |
|   |   |   |   |   |   |
|
|   |   |
|   |   |   |   |   |   |   | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |
|   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |
|   |   |
|   |   |
|   |   |   |   |   | . | . | . | . | . |   |
|
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |
|
|   |   |   |
|
Template Sequence |   |
K | P | V | V | D | K | L | V | K | S | L | Q | A | G | L | . |
. |
. |
. |
. |
A | D | P | K | F | Q | E | R | X | K | Q | L | G | A | E | V | L | T | N | E | A | N | P | E | A | L | Q | A | K | V | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
K | Q | Q | V | P | Q | W | A | E | L | F | K | K | A | G |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . |  |
|  |  |  |  |  |  |  |  |  | T | T |
|  |  |
| G | G | G |
| S |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
237 | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | |
|
|
|
|
. | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . |
  |
  |   |
297 | . | . | 300 | . |
Predicted Secondary structure |   |
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
Query Sequence |   |
L | V | P | K | K |
Query Conservation |   |
  |
|   |   |   |
Alig confidence |   |
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |
Template Sequence |   |
V | E | K | Q | D |
Template Known Secondary structure |   |
|
|
|
|
|
Template Predicted Secondary structure |   |
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
  |   |
297 | . | . | 300 | . |
  |