Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP46474
DateThu Jan 5 12:04:13 GMT 2012
Unique Job ID742fb653648234e4

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c1x4qA_
Top template information
PDB header:rna binding protein
Chain: A: PDB Molecule:u4/u6 small nuclear ribonucleoprotein prp3;
PDBTitle: solution structure of pwi domain in u4/u6 small nuclear2 ribonucleoprotein prp3(hprp3)
Confidence and coverage
Confidence: 13.3% Coverage: 2%
20 residues ( 2% of your sequence) have been modelled with 13.3% confidence by the single highest scoring template.
You may wish to submit your sequence to Phyrealarm. This will automatically scan your sequence every week for new potential templates as they appear in the Phyre2 library.
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3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MRRLPGILLLTGAALVVIAALLVSGLRIALPHLDAWRPEILNKIESATGMPVEASQLSAS
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   .........70.........80.........90.........100.........110.........120
Sequence  WQNFGPTLEAHDIRAELKDGGEFSVKRVTLALDVWQSLLHMRWQFRDLTFWQLRFRTNTP
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   .........130.........140.........150.........160.........170.........180
Sequence  ITSGGSDDSLEASHISDLFLRQFDHFDLRDSEVSFLTPSGQRAELAIPQLTWLNDPRRHR
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   .........190.........200.........210.........220.........230.........240
Sequence  AEGLVSLSSLTGQHGVMQVRMDLRDDEGLLSNGRVWLQADDIDLKPWLGKWMQDNIALET
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   .........250.........260.........270.........280.........290.........300
Sequence  AQFSLEGWMTIDKGDVTGGDVWLKQGGASWLGEKQTHTLSVDNLTAHITRENPGWQFSIP
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   .........310.........320.........330.........340.........350.........360
Sequence  DTRITMDGKPWPSGALTLAWIPEQDVGGKDNKRSDELRIRASNLELAGLEGIRPLAAKLS
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   .........370.........380.........390.........400.........410.........420
Sequence  PALGDVWRSTQPSGKINTLALDIPLQAADKTRFQASWSDLAWKQWKLLPGAEHFSGTLSG
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   .........430.........440.........450.........460.........470.........480
Sequence  SVENGLLTASMKQAKMPYETVFRAPLEIADGQATISWLNNNKGFQLDGRNIDVKAKAVHA
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   .........490.........500.........510.........520.........530.........540
Sequence  RGGFRYLQPANDEPWLGILAGISTDDGSQAWRYFPENLMGKDLVDYLSGAIQGGEADNAT
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   .........550.........560.........570.........580.........590.........600
Sequence  LVYGGNPQLFPYKHNEGQFEVLVPLRNAKFAFQPDWPALTNLDIELDFINDGLWMKTDGV
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   .........610.........620.........630.........640.........650.........660
Sequence  NLGGVRASNLTAVIPDYSKEKLLIDADIKGPGKAVGPYFDETPLKDSLGATLQELQLDGD
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   .........670.........680.........690.........700.........710.........720
Sequence  VNARLHLDIPLNGELVTAKGEVTLRNNSLFIKPLDSTLKNLSGKFSFINSDLQSEPLTAS
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   .........730.........740.........750.........760.........770.........780
Sequence  WFNQPLNVDFSTKEGAKAYQVAVNLNGNWQPAKTGVLPEAVNEALSGSVAWDGKVGIDLP
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   .........790.........800.........810.........820.........830.........840
Sequence  YHAGATYNIELNGDLKNVSSHLPSPLAKPAGEPLAVNVKVDGNLNSFELTGQAGADNHFN
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   .........850.........860.........870.........880.........890.........900
Sequence  SRWLLGQKLTLDRAIWAADSKTLPPLPEQSGVELNMPPMNGAEWLALFQKGAAESVGGAA
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   .........910.........920.........930.........940.........950.........960
Sequence  SFPQHITLRTPMLSLGNQQWNNLSIVSQPTANGTLVEAQGREINATLAMRNNAPWLANIK
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   .........970.........980.........990.........1000.........1010.........1020
Sequence  YLYYNPSVAKTRGDSTPSSPFPTTERINFRGWPDAQIRCTECWFWGQKFGRIDSDITISG
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   .........1030.........1040.........1050.........1060.........1070.........1080
Sequence  DTLTLTNGLIDTGFSRLTADGEWVNNPGNERTSLKGKLRGQKIDAAAEFFGVTTPIRQSS
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   .........1090.........1100.........1110.........1120.........1130.........1140
Sequence  FNVDYDLHWRKAPWQPDEATLNGIIHTQLGKGEITEINTGHAGQLLRLLSVDALMRKLRF
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   .........1150.........1160.........1170.........1180.........1190.........1200
Sequence  DFRDTFGEGFYFDSIRSTAWIKDGVMHTDDTLVDGLEADIAMKGSVNLVRRDLNMEAVVA
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   .........1210.........1220.........1230.........1240.........1250.........1260
Sequence  PEISATVGVAAAFAVNPIVGAAVFAASKVLGPLWSKVSILRYHISGPLDDPQINEVLRQP
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   ......
Sequence  RKEKAQ
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Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 1x4q chain A

3D model

Region: 32 - 51
Aligned: 20
Modelled: 20
Confidence: 13.3%
Identity: 25%
PDB header:rna binding protein
Chain: A: PDB Molecule:u4/u6 small nuclear ribonucleoprotein prp3;
PDBTitle: solution structure of pwi domain in u4/u6 small nuclear2 ribonucleoprotein prp3(hprp3)

Phyre2

PDB 3my2 chain A

3D model

Region: 1147 - 1200
Aligned: 54
Modelled: 54
Confidence: 11.8%
Identity: 9%
PDB header:transport protein
Chain: A: PDB Molecule:lipopolysaccharide export system protein lptc;
PDBTitle: crystal structure of lptc

Phyre2

PDB 2aya chain A

3D model

Region: 34 - 54
Aligned: 21
Modelled: 21
Confidence: 7.6%
Identity: 14%
PDB header:transferase
Chain: A: PDB Molecule:dna polymerase iii subunit tau;
PDBTitle: solution structure of the c-terminal 14 kda domain of the2 tau subunit from escherichia coli dna polymerase iii

Phyre2

PDB 2qts chain A

3D model

Region: 1 - 28
Aligned: 28
Modelled: 28
Confidence: 7.3%
Identity: 11%
PDB header:membrane protein
Chain: A: PDB Molecule:acid-sensing ion channel;
PDBTitle: structure of an acid-sensing ion channel 1 at 1.9 a resolution and low2 ph

Phyre2

PDB 2axt chain J domain 1

3D model

Region: 6 - 29
Aligned: 24
Modelled: 24
Confidence: 7.2%
Identity: 21%
Fold: Single transmembrane helix
Superfamily: Photosystem II reaction center protein J, PsbJ
Family: PsbJ-like

Phyre2

PDB 3ixz chain B

3D model

Region: 1 - 38
Aligned: 38
Modelled: 38
Confidence: 7.0%
Identity: 21%
PDB header:hydrolase
Chain: B: PDB Molecule:potassium-transporting atpase subunit beta;
PDBTitle: pig gastric h+/k+-atpase complexed with aluminium fluoride

Phyre2

PDB 1v54 chain G

3D model

Region: 1 - 23
Aligned: 23
Modelled: 23
Confidence: 6.7%
Identity: 13%
Fold: Single transmembrane helix
Superfamily: Mitochondrial cytochrome c oxidase subunit VIa
Family: Mitochondrial cytochrome c oxidase subunit VIa

Phyre2
1

c1x4qA_
2

c3my2A_
3

c2ayaA_
4

c2qtsA_
5

d2axtj1
6

c3ixzB_
7

d1v54g_



Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c1x4qA_



13.3 25 PDB header:rna binding protein
Chain: A: PDB Molecule:u4/u6 small nuclear ribonucleoprotein prp3;
PDBTitle: solution structure of pwi domain in u4/u6 small nuclear2 ribonucleoprotein prp3(hprp3)
2c3my2A_



11.8 9 PDB header:transport protein
Chain: A: PDB Molecule:lipopolysaccharide export system protein lptc;
PDBTitle: crystal structure of lptc
3c2ayaA_



7.6 14 PDB header:transferase
Chain: A: PDB Molecule:dna polymerase iii subunit tau;
PDBTitle: solution structure of the c-terminal 14 kda domain of the2 tau subunit from escherichia coli dna polymerase iii
4c2qtsA_



7.3 11 PDB header:membrane protein
Chain: A: PDB Molecule:acid-sensing ion channel;
PDBTitle: structure of an acid-sensing ion channel 1 at 1.9 a resolution and low2 ph
5d2axtj1



7.2 21 Fold:Single transmembrane helix
Superfamily:Photosystem II reaction center protein J, PsbJ
Family:PsbJ-like
6c3ixzB_



7.0 21 PDB header:hydrolase
Chain: B: PDB Molecule:potassium-transporting atpase subunit beta;
PDBTitle: pig gastric h+/k+-atpase complexed with aluminium fluoride
7d1v54g_



6.7 13 Fold:Single transmembrane helix
Superfamily:Mitochondrial cytochrome c oxidase subunit VIa
Family:Mitochondrial cytochrome c oxidase subunit VIa

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0