|   |
5 | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | |
. | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | |
|
. | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  | . |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
K | Q | R | N | R | R | W | V | L | A | S | R | P | H | G | A | P | V | P | E | N | F | R | L | . |
E | E | D | D | V | A | T | P | G | E | G | Q | V | L | L | R | T | V | Y | L | S | L | D | P | Y | M | R | G | R | M | S | D | E | P | S | Y | . |
. |
S | P | P | V | D | I | G | G | V | M | V | G | G | T | V | S | R |
Query Conservation |   |
  |   |   |   |
|
|   |
|
|   |   |   |   |   |
|   |   |   |
|   |   |
|   |
| . |   |   |   |
|   |
|   |
|   |   |   |
|
|
|
|
|
|   |
|   |
|
|   |   |   |
|   |   |   |   |   |
|   |   |   |   | . | . |   |   |
|   |
|   |
|   |
|   |   |
|   |
|
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
Template Conservation |   |
  |   |   |
|
|
|   |
|   |   |   |   | . | . |   |   |   |   |   |   |   |
|   |   |
|   |
|
|
|   |
|   |
|   |   |   |
|
|
|
|
|
|   |
|   |
|
|
|   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |
|   |
|
|
|   |   |
|   |
|
|   | . |
Template Sequence |   |
Q | S | M | M | Q | K | L | V | V | T | R | L | . |
. |
S | P | N | F | R | E | A | V | T | L | S | R | D | C | P | V | P | L | P | G | D | G | D | L | L | V | R | N | R | F | V | G | V | N | A | S | D | I | N | Y | S | A | G | R | Y | D | P | S | V | K | P | P | F | D | I | G | F | E | G | I | G | E | V | V | A | . |
Template Known Secondary structure |   |
|
|  |  |  |  |  |  |  |
| S |
| . | . |
| S | S |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
| T | T |  |  |  |  |  |  |  |  |  |  |
|
| T | T |  |  |  |  |  | T | T | T | T |
| T | T |
|
| S |
|  |  |
|
| S |  |  |  |  |  |  |  |  | . |
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |
|
| . | . |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
21 | . | . | . | . | . | . | . | . | 30 | . | . | |
|
. | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | |
  |
  |   |
82 | . | . | . | . | . | . | . | |
90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
| . |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | V | E | S | N | H | P | D | . |
Y | Q | S | G | D | W | V | L | G | Y | S | G | W | Q | D | Y | D | I | S | S | G | D | D | L | V | K | L | G | D | H | P | Q | N | P | S | W | S | L | G | V | L | G | M | P | G | F | T | A | Y | M | G | L | L | D | I | G | Q | P | K | E | G | E | T | L | V | V | A | A | A | T | G |
Query Conservation |   |
  |
|
|   |   |
|   |   | . |   |   |   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
. |
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
Template Conservation |   |
. |
|
|   |   |
|   |   |   |   |   |   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . |   |   |   |
Template Sequence |   |
. |
L | G | L | S | A | S | A | R | Y | T | V | G | Q | A | V | A | Y | M | A | P | G | S | F | A | E | Y | T | V | V | P | A | S | I | A | T | P | V | P | S | V | K | P | E | Y | L | T | L | L | V | S | G | T | T | A | Y | I | S | L | K | E | L | G | G | L | S | E | G | K | K | V | L | V | T | . |
. |
. |
A | A | A |
Template Known Secondary structure |   |
. |  |
| T | T | S |
| T | T |
|
| T | T |
|  |  |  |  |  |
| S |
|
| S | B | S |  |  |  |  |  | G | G | G |
|  |  |
| S | S |
|
|  |  |  |  |  |  |  | T |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
|
| T | T |
|  |  |  |  | T | . | . | . | T | T | T |
Template Predicted Secondary structure |   |
. |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
| . | . | . |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
98 | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | |
|
|
. | . | . |
  |
  |   |
161 | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 |
Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
P | V | G | A | T | V | G | Q | I | G | K | L | K | G | C | R | V | V | G | V | A | G | G | A | E | K | C | R | H | A | T | E | V | L | G | F | D | V | C | L | D | H | H | A | D | D | F | A | E | Q | L | A | K | A | C | P | K | G | I | D | I | Y | Y | E | N | V | G | G | K | V | F | D | A | V | L | P | L | L | N | T |
Query Conservation |   |
  |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
G | G | T | G | Q | F | A | M | Q | L | S | K | K | A | K | C | H | V | I | G | T | C | S | S | D | E | K | S | A | F | L | K | S | L | G | C | D | R | P | I | N | Y | K | T | E | P | V | G | T | V | L | K | Q | E | Y | P | E | G | V | D | V | V | Y | E | S | V | G | G | A | M | F | D | L | A | V | D | A | L | A | T |
Template Known Secondary structure |   |
B | T | T |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |  | S | S |  |  |  |  |  |  |  |  |  | T | T |
| S |  |  |  |  | T | T | T | S |
|  |  |  |  |  |  |  |  |
| T | T |
|  |  |  |  |  |  |
| S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
174 | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . |
  |
  |   |
241 | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | |
|
|
|
|
|
|
|
. | . |
Predicted Secondary structure |   |
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
|
|
Query Sequence |   |
S | A | R | I | P | V | C | G | L | V | S | S | Y | N | A | T | E | L | P | P | G | P | D | R | L | P | L | L | M | A | T | V | L | K | K | R | I | R | L | Q | G | F | I | I | A | Q | D | Y | G | H | R | I | H | E | F | Q | R | E | M | G | Q | W | V | K | E | D | K | I | H | Y | . |
. |
. |
. |
. |
. |
. |
. |
R | E |
Query Conservation |   |
  |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |
|   |   | . | . | . | . | . | . | . | . |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
Template Conservation |   |
  |
|   |   |   |   |   |
| . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |
|
Template Sequence |   |
K | G | R | L | I | V | I | G | . |
F | I | S | G | Y | Q | T | P | T | G | L | S | P | V | K | A | G | T | L | P | A | K | L | L | K | K | S | A | S | V | Q | G | F | F | L | N | H | Y | L | . |
S | K | Y | Q | A | A | M | S | H | L | L | E | M | C | V | S | G | D | L | V | C | E | V | D | L | G | D | L | S | P | E |
Template Known Secondary structure |   |
 |  |  |  |  |  |
|
| . |
| G | G | G | T | T | S | S | S | S |
|
|
|
|
|
| T | T |  |  |  |  |  |  |  |  | T |
|  |  |  |  |
|
| G | G | G |
| G | . | G | G |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S | S |
|
|
|  |  |
| S | T | T | S | T | T |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|
| . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
254 | . | . | . | . | . | 260 | . | |
. | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | |
. | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . |
  |
  |   |
313 | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | I | T | D | G | L | E | N | A | P | Q | T | F | I | G | L | L | K | G | K | N | F | G | K | V | V | I | R | V |
Query Conservation |   |
  |   |   |   |   |
|   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |
|
|
|
|
|   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |
|
|
|
|
|   |
|
Template Sequence |   |
G | R | F | T | G | L | E | S | I | F | R | A | V | N | Y | M | Y | M | G | K | N | T | G | K | I | V | V | E | L |
Template Known Secondary structure |   |
| S |
| B | S | G | G | G |  |  |  |  |  |  |  |  |  | T | T |
|
|
| B |  |  |  |  |  |
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
332 | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 |
  |