Job Description P04693 Confidence 99.95% Date Thu Jan 5 10:58:18 GMT 2012 Rank 117 Aligned Residues 332 % Identity 17% Template c3e9kA_ PDB info PDB header:hydrolase Chain: A: PDB Molecule:kynureninase; PDBTitle: crystal structure of homo sapiens kynureninase-3-hydroxyhippuric acid2 inhibitor complex Resolution 1.70 Å

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		35	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.								.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.
Predicted Secondary structure																					.	.	.	.	.	.	.
Query SS confidence																					.	.	.	.	.	.	.
Query Sequence		L	Y	Y	N	E	D	G	I	I	P	Q	L	Q	A	V	A	E	A	E	.	.	.	.	.	.	.	A	R	L	N	A	Q	P	H	G	A	S	L	Y	L	P	M	E	G	L	N	C	Y	R	H	A	I	A	P	L	L	F	G	A	D	H	P	V	L	K	Q	Q	R	V	A	T	I	Q	T	L	G	G	S	G	A
Query Conservation																					.	.	.	.	.	.	.
Alig confidence																					.	.	.	.	.	.	.																															.	.	.	.	.	.										.	.
Template Conservation																																																										.	.	.	.	.	.										.	.
Template Sequence		I	Y	F	L	G	N	S	L	G	L	Q	P	K	M	V	K	T	Y	L	E	E	E	L	D	K	W	A	K	I	A	A	Y	G	H	E	V	G	K	R	P	W	I	T	G	D	E	S	I	V	G	L	M	K	D	I	V	.	.	.	.	.	.	G	A	N	E	K	E	I	A	L	.	.	M	N	A	L	T	V	N
Template Known Secondary structure					B	T	T	T	S			B		T	T																G	G	G	G	G	T	S	S	S	S		G	G	G	T	T					G	G	G					.	.	.	.	.	.	T			G	G	G				.	.		S
Template Predicted Secondary structure																																																										.	.	.	.	.	.										.	.
Template SS confidence
		69	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.							.	.	.	.	.	130	.	.	.			.	.	.	.	.	.	140
		108	.	110	.	.	.	.	.	.	.	.	.	120				.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.										.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.
Predicted Secondary structure															.	.	.																						.	.	.	.	.	.	.	.	.
Query SS confidence															.	.	.																						.	.	.	.	.	.	.	.	.
Query Sequence		L	K	V	G	A	D	F	L	K	R	Y	F	P	.	.	.	E	S	G	V	W	V	S	D	P	T	W	E	N	H	V	A	I	F	A	G	A	.	.	.	.	.	.	.	.	.	G	F	E	V	S	T	Y	P	W	Y	D	E	A	T	N	G	V	R	F	N	D	L	L	A	T	L	K	T	L	P	A	R	S	I
Query Conservation															.	.	.																						.	.	.	.	.	.	.	.	.
Alig confidence										.	.				.	.	.																						.	.	.	.	.	.	.	.	.													.	.
Template Conservation										.	.																																																	.	.
Template Sequence		L	H	L	L	M	L	S	F	.	.	F	K	P	T	P	K	R	Y	K	I	L	L	E	A	K	A	F	P	S	D	H	Y	A	I	E	S	Q	L	Q	L	H	G	L	N	I	E	E	S	M	R	M	I	K	P	R	E	G	E	.	.	E	T	L	R	I	E	D	I	L	E	V	I	E	K	E	G	D	S	I	A
Template Known Secondary structure										.	.					S	S	S							T	T																T	T														T	T		.	.	S	S														G	G	G
Template Predicted Secondary structure										.	.																																																	.	.
Template SS confidence
		141	.	.	.	.	.	.	.			.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.			.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.
		176	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		V	L	L	H	P	C	C	H	N	P	T	G	A	D	L	T	N	D	Q	W	D	A	V	I	E	I	L	K	A	R	E	L	I	P	F	L	D	I	A	Y	Q	G	F	G	A	G	M	E	E	D	A	Y	A	I	R	A	I	A	S	A	G	L	P	A	L	V	S	N	S	F	S	K	I	F	S	L	Y	G	E	R
Query Conservation
Alig confidence																		.	.	.																														.	.	.	.	.	.	.	.	.
Template Conservation																		.	.	.																														.	.	.	.	.	.	.	.	.
Template Sequence		V	I	L	F	S	G	V	H	F	Y	T	G	Q	H	F	N	.	.	.	I	P	A	I	T	K	A	G	Q	A	K	G	C	Y	V	G	F	D	L	A	H	A	V	G	N	V	E	L	Y	.	.	.	.	.	.	.	.	.	L	H	D	W	G	V	D	F	A	C	W	C	S	Y	K	Y	L	N	A	G	A	G	G
Template Known Secondary structure							S	B		T	T	T		B	B			.	.	.											T	T								T	T	T	T	T	T	S				.	.	.	.	.	.	.	.	.					T								S	S	S	T	T				T	T
Template Predicted Secondary structure																		.	.	.																														.	.	.	.	.	.	.	.	.
Template SS confidence
		217	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.				.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.										.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.
		256	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.																			.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.
Predicted Secondary structure																				.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence																				.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		V	G	G	L	S	V	M	C	E	D	A	E	A	A	G	R	V	L	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	G	Q	L	K	A	T	V	R	R	N	Y	S	S	P	P	N	F	G	A	Q	V	V	A	A	V	L	N	D	E	A	L	K	A	S	W	L	A	E	V	E	E	M	R	T
Query Conservation																				.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence																				.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																															.	.	.	.	.
Template Conservation																																																																				.	.	.	.	.
Template Sequence		I	A	G	A	F	I	H	E	K	H	A	H	T	I	K	P	A	L	V	G	W	F	G	H	E	L	S	T	R	F	K	M	D	N	K	L	Q	L	I	P	G	V	C	G	F	R	I	S	N	P	P	I	L	L	V	C	S	L	H	A	S	L	E	I	F	K	.	.	.	.	.	Q	A	T	M	K	A	L	R	K
Template Known Secondary structure									G	G	G	T	T	T	S			S	S			G	G	G	B						T	T			S				B		S	S	G	G	G	G			S																			.	.	.	.	.
Template Predicted Secondary structure																																																																				.	.	.	.	.
Template SS confidence
		285	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350						.	.	.	.	.	.	.	.	.
		318	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.					.	.	.	350	.	.	.	.	.			.	.	.	.	360	.	.	.	.	.	.	.	.	.	370					.	.	.	.	.	.	.	.	.	380	.			.	.	.	.
Predicted Secondary structure																															.	.	.	.										.	.																.	.	.	.												.	.
Query SS confidence																															.	.	.	.										.	.																.	.	.	.												.	.
Query Sequence		R	I	L	A	M	R	Q	E	L	V	K	V	L	S	T	E	M	P	E	R	N	F	D	Y	L	L	N	Q	R	.	.	.	.	G	M	F	S	Y	T	G	L	S	.	.	A	A	Q	V	D	R	L	R	E	E	F	G	V	Y	L	.	.	.	.	I	A	S	G	R	M	C	V	A	G	L	.	.	N	T	A	N
Query Conservation																															.	.	.	.										.	.																.	.	.	.												.	.
Alig confidence																					.	.									.	.	.	.										.	.																.	.	.	.												.	.
Template Conservation																					.	.
Template Sequence		K	S	V	L	L	T	G	Y	L	E	Y	L	I	K	H	N	Y	G	V	.	.	V	N	I	I	T	P	S	H	V	E	E	R	G	C	Q	L	T	I	T	F	S	V	P	N	K	D	V	F	Q	E	L	E	K	R	G	V	V	C	D	K	R	N	P	N	G	I	R	V	A	P	V	P	L	Y	N	S	F	H	D
Template Known Secondary structure																					.	.					S		S	S	G	G	G	B		S									T	T									T	T	T							T	T	T					B			T	T	T
Template Predicted Secondary structure																					.	.
Template SS confidence
		360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.			.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.
		386	.	.	.	390	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		V	Q	R	V	A	K	A	F	A	A	V	M
Query Conservation
Alig confidence
Template Conservation
Template Sequence		V	Y	K	F	T	N	L	L	T	S	I	L
Template Known Secondary structure
Template Predicted Secondary structure
Template SS confidence
		447	.	.	450	.	.	.	.	.	.	.	.

No model constructed - rank, confidence too low

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Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions