|   |
145 | . | . | . | . | 150 | |
. | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  | . |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | I | T | Y | H | S | . |
N | A | L | Q | S | E | R | Q | M | Y | V | W | T | P | P | G | Y | T | G | M | G | E | P | L | P | V | L | Y | F | Y | H | G | F | G | D | T | G | R | S | A | I | D | Q | G | R | I | P | Q | I | M | D | N | L | L | A | E | G | K | I | K | P | M | L | V | V | I | P | D | T | E | T | D | A |
Query Conservation |   |
  |   |   |   |   |
| . |   |   |   |
|   |   |   |   |   |   |
|
|   |
|   |   |
|   |   |   |   |   |   |
|
|
|
|   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|   |   |   |   |   |   |   |
|
|
|   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   | . | . |   |   |   |   | . | . |   |   |
|
|   |
|
|
|
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . |   |   |
|   |   |
|
|   |   |
|   |
|
|   |   |
Template Sequence |   |
E | I | K | Y | K | V | I | T | K | D | A | F | A | L | P | Y | T | I | I | K | A | K | N | . |
. |
Q | P | T | K | . |
. |
G | V | I | V | Y | I | H | G | G | G | L | M | F | G | K | A | N | D | L | S | P | Q | Y | I | D | I | L | . |
. |
. |
. |
. |
. |
. |
T | E | H | Y | D | L | I | Q | L | S | Y | R | L | L | P |
Template Known Secondary structure |   |
|  |  |  |  |  |  |
| T | T | S |
|  |  |  |  |  |  |  |
|
| S | S | . | . | S | S |
| S | . | . |  |  |  |  |  |  |
|
| S | T | T | T | S |
|
| T | T |
| S |
|  |  |  |  |  |  |  | . | . | . | . | . | . | . | T | T | T |  |  |  |  |  |  |
|
|
|
| T | T |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
| . | . |
|
|
|
| . | . |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
3 | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | |
|
. | . | . | . | |
|
30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | |
|
|
|
|
|
|
. | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . |
  |
  |   |
224 | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
K | G | I | I | P | E | D | F | V | P | Q | E | R | R | K | V | F | Y | P | L | N | A | K | A | A | D | R | E | L | M | N | D | I | I | P | L | I | S | K | R | F | N | V | R | K | D | A | D | G | R | A | L | A | G | L | S | Q | G | G | Y | Q | A | L | V | S | G | M | N | H | L | E | S | F | G | W | L | A | T | F | S |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |
|   |
|
|   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |
|   |
|   |
|
|   |   |
|
|   |   |   |   |   |   |
|
|   |
|   |   |   |   |   |   |
|
Alig confidence |   |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
Template Conservation |   |
  |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . |   |   |   |   |   |   |
|   |
|   |
|   |
|
|   |
|
|   |   |   |
|   |   |   |
|   |   | . | . |   |   |   |   |   |   |
Template Sequence |   |
E | V | S | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
L | D | C | I | I | E | D | V | Y | A | S | F | D | A | I | Q | S | Q | Y | . |
. |
. |
. |
S | N | C | P | I | F | T | F | G | R | S | S | G | A | Y | L | S | L | L | I | A | R | D | R | D | I | D | . |
. |
G | V | I | D | F | Y |
Template Known Secondary structure |   |
T | S |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | . | . | . | . | T | T | S |
|  |  |  |  |  |  | T |  |  |  |  |  |  |  |  |  |  |  |  | S |
|
| S | . | . |  |  |  |  |  | S |
Template Predicted Secondary structure |   |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . | . | . |
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
| . | . |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
72 | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | |
|
|
|
. | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | |
|
. | . | . | . | . | . |
  |
  |   |
304 | . | . | . | . | . | 310 | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | V | T | T | T | T | V | P | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
D | E | G | V | A | A | R | L | N | D | P | A | A | I | N |
Query Conservation |   |
|   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
G | Y | S | R | I | N | T | E | P | F | K | T | T | N | S | Y | Y | A | K | I | A | Q | S | I | N | E | T | M | I | A | Q | L | T | S | P | T | P | V | V | Q | D | Q | I | A | Q | R | F | L | I | Y | V | Y | A | R | G | T | G | K | W | I | N | M | I | N | I | A | D | Y | T | D | S | K | Y | N | I | A | P | D | E | L |
Template Known Secondary structure |   |
|
| S |
| S |
| S |  |  |  |  | S |
|
|  |  |  |  |  |  |  | T | T | S |
|  |  |  |  |  | T | T | S |
| S | S |
|
| S | S |
| S | S | G | G | G |  |  |  |  |  |  |  |  |  |  | T |
|  |  |  |  |  |
|
| S |
| T | T | S | G | G | G | S |
|
|  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
127 | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . |
  |
  |   |
327 | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | |
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
| . | . | . | . | . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Q | Q | L | R | N | F | T | V | V | V | G | D | K | D | V | V | T | G | K | D | I | A | G | L | K | T | E | L | E | Q | K | K | I | N | F | D | Y | Q | E | Y | P | G | L | N | H | . |
. |
. |
. |
. |
. |
. |
. |
E | M | D | V | W | R | P | A | Y | A | A | F | V | Q | K | L |
Query Conservation |   |
  |   |   |   |   |   |   |
|   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |
|
| . | . | . | . | . | . | . | . |   |
|   |   |
|
|   |   |
|   |   |   |   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |
|   |
|
|
|   |
|   |   |
|   |   |   |
|   | . | . | . |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |   |
Template Sequence |   |
K | T | L | P | P | V | F | I | A | H | C | N | G | D | Y | D | V | P | V | . |
. |
. |
E | E | S | E | H | I | M | N | H | V | P | H | S | T | F | E | R | V | N | K | N | E | H | D | F | D | R | R | P | N | D | E | A | I | T | I | Y | R | K | V | V | D | F | L | N | A | I |
Template Known Secondary structure |   |
T | T |
|
|
|  |  |  |  |  |  | T | T |
| S | S | S |
| T | . | . | . |  |  |  |  |  |  |  | T | T |
| S | S |  |  |  |  |  |  |
| S | S |
| S |
| T | T | S | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  | . | . | . |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
207 | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | |
|
|
. | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . |
  |