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Job DescriptionP0AES6
Confidence99.88%DateThu Jan 5 11:24:06 GMT 2012
Rank27Aligned Residues350
% Identity20%Templatec2q2eB_
PDB info PDB header:isomeraseChain: B: PDB Molecule:type 2 dna topoisomerase 6 subunit b; PDBTitle: crystal structure of the topoisomerase vi holoenzyme from2 methanosarcina mazei
Resolution4.00 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


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Query Sequence  SSIKVLKGLDAVRKRPGMYIGDTDDGTGLHHMVFEVVDNAIDE. ALAGHCKEIIVTIHADNS. . . . VSVQDDGRGIPTGI
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Template Sequence  KKQKSISVAEFFEKNRQILGFDS. APRSLITTVKEAVDNALDACEEAGILPDILVQVERTGPDYVTVIIEDNGPGIVRE.
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   83......90.........100.........110......... 120.........130.........140..... ....150. ....
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Query Sequence  HPEEGVSAAEVIMTVLHAGGKFDDNSYKVSGGLHGVG. . VSVVNALSQKLELVIQREGKIHRQIY. . . . EHGVPQ. APLA
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Template Sequence  . . . . . . . QIPKVFAKLLYGFHALKSRGQQGIGISAAVLYAQMTAGRHTKILSKTSPTAPAHYYELMINTSTNEPDILVDE
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   8990.........100.........110.........120.........130.........140.........150.........160.
 
   156...160.........170.........180.........190.........200.........210...
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Query Sequence  VTGETEKTGTMVRFWPSLETFTNVTEFEYEILAKRLRELSFLNSGVSIRLRDKRDGKE. . . . . . . . . . . . . . . . . . . . . .
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Template Sequence  VRDWFRPHGTQIEL. . . . EMRAAYVKGRRQSIYEYLKATAIVNPHARITLIDPDGNEEVFERATDKMPEPAEEILPHPEG
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   165....170........ .180.........190.........200.........210.........220.........230.........240
 
   214.....220.........230........
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . DHFHYEGGIKAFVEYLNKNKTPIHP. . . . . . .
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Template Sequence  IELGTLMKMLHYTEPFLRYSFCKLLTAEEICKAAGLDPEIDPHALGRHEARKLIEAFEKV. KIMAPPTDCLSPIGEDLIY
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   241........250.........260.........270.........280.........290.........300 .........310.........
 
   239240.........250......... 260.........270.........280.........290.......
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Query Sequence  . . . . . . . . . . . . . . . . . NIFYFSTEKDGIGVEVALQWN. . . . DGFQENIYCFTNNIPQRDGGTHLAGFRAAMTRTLNAYM
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Template Sequence  RGLEKETTVDFIATSTRKPAVYSGN. . PFVVEVGMAYGGNLPKEEKISIMRFANRVPLLY. . . . . . . . . QQGGCVTTHAV
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B


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   327..330.........340.........350. ........360.........370.........380.... .....390.....
 
   298.300.........310.........320.........330.........340.. .......350.........360.........370......
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Query Sequence  DKEGYSKKAKVSATGDDAREGLIAVVSVKVPDPKFSSQTKDKLVS. SEVKSAVEQQMNELLAEYLLENPTDAKIVVGKII
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Template Sequence  EDIKWKQYGLNQPGGGIPVGPVILLIHVASINVPFTSESKDAIADIPVIKEEIDLAI. . . . . . . . . . . KEVARKLKHYLS
Template Known Secondary structure  S

TTTT



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   396...400.........410.........420.........430.........440.........450.. .......460....
 
   377..380.........390...
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Query Sequence  DAARAREAARRAREMTR
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Template Sequence  KQSNLKKRREKEIIITK
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   465....470.........480.
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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