Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	I	G	R	I	S	R	F	M	T	R	F	V	S	R	W	L	P	D	P	L	I	F	A	M	L	L	T	L	L	T	F	V	I	A	L	W	L	T	P	Q	T	P	I	S	M	V	K	M	W	G	D	G	F	W	N	L	L	A	F
Secondary structure
SS confidence
Disorder		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		G	M	Q	M	A	L	I	I	V	T	G	H	A	L	A	S	S	A	P	V	K	S	L	L	R	T	A	A	S	A	A	K	T	P	V	Q	G	V	M	L	V	T	F	F	G	S	V	A	C	V	I	N	W	G	F	G	L	V	V	G
Secondary structure
SS confidence
Disorder																?															?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		A	M	F	A	R	E	V	A	R	R	V	P	G	S	D	Y	P	L	L	I	A	C	A	Y	I	G	F	L	T	W	G	G	G	F	S	G	S	M	P	L	L	A	A	T	P	G	N	P	V	E	H	I	A	G	L	I	P	V	G	D
Secondary structure
SS confidence
Disorder																																											?	?		?	?	?						?	?	?	?	?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		T	L	F	S	G	F	N	I	F	I	T	V	A	L	I	V	V	M	P	F	I	T	R	M	M	M	P	K	P	S	D	V	V	S	I	D	P	K	L	L	M	E	E	A	D	F	Q	K	Q	L	P	K	D	A	P	P	S	E	R	L
Secondary structure
SS confidence
Disorder		?	?																											?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		E	E	S	R	I	L	T	L	I	I	G	A	L	G	I	A	Y	L	A	M	Y	F	S	E	H	G	F	N	I	T	I	N	T	V	N	L	M	F	M	I	A	G	L	L	L	H	K	T	P	M	A	Y	M	R	A	I	S	A	A	A
Secondary structure
SS confidence
Disorder		?																												?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		R	S	T	A	G	I	L	V	Q	F	P	F	Y	A	G	I	Q	L	M	M	E	H	S	G	L	G	G	L	I	T	E	F	F	I	N	V	A	N	K	D	T	F	P	V	M	T	F	F	S	S	A	L	I	N	F	A	V	P	S	G
Secondary structure
SS confidence
Disorder																																					?		?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		G	G	H	W	V	I	Q	G	P	F	V	I	P	A	A	Q	A	L	G	A	D	L	G	K	S	V	M	A	I	A	Y	G	E	Q	W	M	N	M	A	Q	P	F	W	A	L	P	A	L	A	I	A	G	L	G	V	R	D	I	M	G
Secondary structure
SS confidence
Disorder																			?
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440
Sequence		Y	C	I	T	A	L	L	F	S	G	V	I	F	V	I	G	L	T	L	F
Secondary structure
SS confidence
Disorder																				?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 3myr chain B Region: 2 - 20 Aligned: 19 Modelled: 19 Confidence: 7.1% Identity: 16% PDB header:oxidoreductase Chain: B: PDB Molecule:nickel-dependent hydrogenase large subunit; PDBTitle: crystal structure of [nife] hydrogenase from allochromatium vinosum in2 its ni-a state Phyre2 PDB 1dv0 chain A Region: 375 - 393 Aligned: 19 Modelled: 19 Confidence: 7.0% Identity: 26% Fold: RuvA C-terminal domain-like Superfamily: UBA-like Family: UBA domain Phyre2 PDB 3d0w chain D Region: 357 - 401 Aligned: 45 Modelled: 45 Confidence: 6.4% Identity: 16% PDB header:structural genomics, unknown function Chain: D: PDB Molecule:yflh protein; PDBTitle: crystal structure of yflh protein from bacillus subtilis.2 northeast structural genomics consortium target sr326 Phyre2 1 c3myrB_ 2 d1dv0a_ 3 c3d0wD_

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c3myrB_ 7.1 16 PDB header:oxidoreductase Chain: B: PDB Molecule:nickel-dependent hydrogenase large subunit; PDBTitle: crystal structure of [nife] hydrogenase from allochromatium vinosum in2 its ni-a state 2 d1dv0a_ 7.0 26 Fold:RuvA C-terminal domain-like Superfamily:UBA-like Family:UBA domain 3 c3d0wD_ 6.4 16 PDB header:structural genomics, unknown function Chain: D: PDB Molecule:yflh protein; PDBTitle: crystal structure of yflh protein from bacillus subtilis.2 northeast structural genomics consortium target sr326

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Transmembrane helix prediction

Transmembrane helices have been predicted in your sequence to adopt the topology shown below

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0