|   |
61 | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 |
Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | A | Y | M | V | P | T | K | Y | G | Q | V | E | T | R | L | F | C | P | Q | P | D | S | P | A | T | L | F | Y | L | H | G | G | G | F | I | L | G | N | L | D | T | H | D | R | I | M | R | L | L | A | S | Y | S | Q | C | T | V | I | G | I | D | Y | T | L | S | P | E | A | R | F | P | Q | A | I | E | E | I | V | A |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |   |   |
|   |
|
|   |   |
|
|
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |
|
|
|
|   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |
|
|   |   |
|   |
|   |   |   |   |   |   |   |   |   |
|   |
|
|
|
|
|
|   |   | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   | . | . |   |   |   |
|
|   |   |
|   |   |
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
E | D | R | Y | W | T | S | S | D | G | L | R | L | H | F | R | A | Y | E | G | D | I | S | R | P | P | V | L | C | L | P | G | L | T | . |
. |
. |
R | N | A | R | D | F | E | D | L | A | T | R | L | A | G | . |
. |
D | W | R | V | L | C | P | E | X | R | G | R | G | D | S | D | Y | A | K | D | P | X | T | Y | Q | P |
Template Known Secondary structure |   |
 |  |  |  |  |  |
| T | T | S |
|  |  |  |  |  |  |  |
| B |
| T | T | S |
|
|  |  |  |  |
|
| T | T | . | . | . |
|
| G | G | G | G |  |  |  |  |  |  |  | B | B | . | . | T | B |
|  |  |  |  |
|
| T | T | B | T | T | S |
|
|
| S | S | G | G | G |
| S |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
| . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
| . | . |
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
5 | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | |
|
|
. | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | |
|
. | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . |
  |
  |   |
141 | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | C | C | Y | F | H | Q | Q | A | E | D | Y | Q | I | N | M | S | R | I | G | F | A | G | D | S | A | G | A | M | L | A | L | A | S | A | L | W | L | R | D | K | Q | I | D | C | G | K | V | A | G | V | L | L | W | Y | G | L | Y | G | L | R | D | S | V | T | R | R | L | L | G | G | V | W | D | G | L | T | Q | Q | D |
Query Conservation |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . |   |   |   |   |   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
X | Q | Y | L | Q | D | L | E | A | L | L | A | Q | E | G | I | E | R | F | V | A | I | G | T | S | L | G | G | L | L | T | X | L | L | A | A | A | . |
. |
. |
. |
. |
. |
N | P | A | R | I | A | A | A | V | L | N | D | V | G | P | E | V | S | P | E | G | L | E | R | I | R | G | Y | V | G | Q | G | R | N | F | E | T |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
| S |  |  |  |  |  |  | T |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . |
| G | G | G |  |  |  |  |  |  |  | S |
|
| S | S |
|
|  |  |  |  |  |  |  |  |  |  | T | T |
|
|
|  |  | S | S |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  | . | . | . | . | . | . |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | |
|
|
|
|
|
. | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . |
  |
  |   |
221 | . | . | . | . | . | . | . | . | 230 | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | Q | M | Y | E | E | A | Y | L | S | N | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
D | A | D | R | E | S | P | Y | Y | C | L | F | N | N | D | L | T | R | E | V | P | P | C | F | I | A | G |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|   |
Template Sequence |   |
W | X | H | A | A | R | A | L | Q | E | S | S | G | D | V | Y | P | D | W | D | I | T | Q | W | L | R | Y | A | K | R | I | X | V | L | G | S | S | G | R | I | A | F | D | Y | D | X | K | I | A | E | P | F | E | A | P | V | G | A | T | P | Q | V | D | X | W | P | L | F | D | A | L | A | T | R | P | L | L | V | L | R |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  | T | T | T | S | T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| T | T | S |
|  |  |  | S | B |
| G | G | G | G |
|
| T | T | S |
| T | T |
|
|
| S | S |
|
|  |  |  |  |  |  |  | T | T | S |
|  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
154 | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . |
  |
  |   |
259 | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | E | F | D | P | L | L | D | D | S | R | L | L | Y | Q | T | L | A | A | H | Q | Q | P | C | E | F | K | L | Y | P | G | T | L | H | A | F | L | H | Y | S | R | M | M | K | T | A | D | E | A | L | R | D | G | A | Q | F | F | T | A |
Query Conservation |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |
|   |   |   |   |
|   |   |
|   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |
|   |   |   |   |   |   |   |   | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
| . |   |   |   |   |
|   |
| . | . | . | . | . |
|   |   |
|   |
|   |   |
|
|   |   |
Template Sequence |   |
G | E | T | S | D | I | L | S | A | Q | T | A | . |
. |
. |
A | K | X | A | S | R | P | G | V | E | L | V | T | L | P | R | I | G | H | . |
A | P | T | L | D | E | P | . |
. |
. |
. |
. |
E | S | I | A | A | I | G | R | L | L | E | R |
Template Known Secondary structure |   |
 | T | T |
| S | S | S |
|  |  |  |  | . | . | . |  |  |  |  | T | S | T | T |  |  |  |  |  |  | T | T |
|
| S | . |
|
|
| S |
| S |  | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  | T | T |
Template Predicted Secondary structure |   |
 |
|
|
|
|
|
|
|  |  |  |  | . | . | . |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
| . |
|  |  |  |
|
|  | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
234 | . | . | . | . | . | 240 | . | . | . | . | . | |
|
|
. | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | |
. | . | . | . | . | 270 | . | |
|
|
|
|
. | . | . | . | . | . | . | . | 280 | . | . | . |
  |