|   |
22 | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | |
. | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | |
|
|
|
|
. |
Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  | . |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |
|
|
|
|
|
|  |  |  | . | . | . | . | . |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
Query Sequence |   |
K | I | N | F | G | V | S | A | T | Y | P | P | F | E | S | I | G | A | N | N | E | I | V | G | F | D | I | D | L | A | K | A | L | C | K | Q | M | Q | A | E | C | T | F | T | N | H | . |
A | F | D | S | L | I | P | S | L | K | F | R | K | Y | D | A | V | I | S | G | M | D | I | T | P | E | R | . |
. |
. |
. |
. |
S |
Query Conservation |   |
  |
|   |
|   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|
|   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
Template Conservation |   |
  |
|
|
|
|   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|   |   |   |
|   |   |   |   |   |   |   |   |
|
|   |
|
|   |
|
|   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |
Template Sequence |   |
K | V | T | I | G | V | A | S | N | D | T | K | A | W | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
E | K | V | K | E | L | A | K | K | D | D | I | D | V | E | I | K | H | F | S | D | Y | N | L | P | N | K | A | L | N | D | G | D | I | D | M | N | A | F | Q | H | F | A | F | L | D | Q | Y | K | K | A | H | K |
Template Known Secondary structure |   |
|  |  |  |  |  | S | S | S |
|
|  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  | G | G | G | T |
|
|  |  |  |  |  |
| S | S | T | T | S |  |  |  |  |  |  | T | T | S | S | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| T |
Template Predicted Secondary structure |   |
|  |  |  |  |  |
|
|
|
|  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . |
  |
  |   |
96 | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . |
Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
Query Sequence |   |
K | Q | V | S | F | T | T | P | Y | Y | E | N | S | A | V | V | I | A | K | K | D | T | Y | K | T | F | A | D | L | K | G | K | R | I | G | M | E | N | G | T | T | H | Q | K | Y | I | Q | D | Q | H | P | E | V | K | T | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
V | S | Y |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
Template Conservation |   |
  |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |
|   |
|
Template Sequence |   |
G | T | K | I | S | A | L | S | T | T | V | L | A | P | L | G | I | Y | S | D | K | I | K | D | V | K | K | V | K | D | G | A | K | V | V | I | P | N | D | V | S | N | Q | A | R | A | L | K | L | L | E | A | A | G | L | I | K | L | K | K | D | F | G | L | A | G | T | V | K | D | I | T | S | N | P | K | H | L | K | I |
Template Known Secondary structure |   |
T |
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
| S | S |
| S |
| G | G | G |
|
| T | T |
|  |  |  |  |  |
| S |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S |
|  |  |
| T | T |
|
| T | T |
|
| G | G | G |  |  |  |
| T | T |
|
|  |  |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
107 | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . |
  |
  |   |
154 | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | |
|
. | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . |
Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
| . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
D | S | Y | Q | N | A | F | I | D | L | K | N | G | R | I | D | G | V | F | G | D | T | A | V | V | N | E | W | L | K | T | N | P | Q | L | G | V | A | T | E | K | V | T | D | P | Q | Y | F | G | T | G | L | G | I | A | V | R | P | D | . |
. |
N | K | A | L | L | E | K | L | N | N | A | L | A | A | I | K | A | D | G |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   | . | . |   |   |   |
|   |   |   |
|
|   |   |
|   |   |
|   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
Template Conservation |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|
|
|   |   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   | . | . | . | . |   |   |   |
Template Sequence |   |
T | A | V | D | A | Q | Q | T | A | R | A | L | S | D | V | D | I | A | V | I | N | N | G | V | A | T | K | A | G | K | D | P | K | N | D | P | I | F | L | E | K | S | N | S | D | A | V | K | P | Y | I | N | I | V | A | V | N | D | K | D | L | D | N | K | T | Y | A | K | I | V | E | L | Y | . |
. |
. |
. |
H | S | K |
Template Known Secondary structure |   |
 |  |  |
| G | G | G | T | T | G | G | G | G | T | S | S |  |  |  |  |
|  |  |  |  |  |  | T | T |
|
| T | T | T | S |
| S |  |  |
|
|
| S | S | G | G | G | G | G | G |  |  |  |  |  |  |  | G | G | G | T | T |
|  |  |  |  |  |  |  |  |  |  | . | . | . | . |  | S |  |
Template Predicted Secondary structure |   |
 |  |
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  | . | . | . | . |
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
187 | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | |
|
|
|
260 | . | . |
  |
  |   |
232 | . | . | . | . | . | . | . | 240 | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | Y | Q | K | I | S | D | Q | W | F | P | Q |
Query Conservation |   |
  |   |   |   |
|   |   |
|
|
|   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|   |   |   |
|   |   |   |   |   |   |
Template Sequence |   |
E | A | Q | K | A | L | Q | E | D | V | K | D |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  | T | T |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
263 | . | . | . | . | . | . | 270 | . | . | . | . |
  |