|   |
1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | |
Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
Query Sequence |   |
M | M | I | N | V | Q | T | V | A | V | I | G | S | G | T | M | G | A | G | I | A | E | V | A | A | S | H | G | H | Q | V | L | L | Y | D | I | S | A | E | A | L | T | R | A | I | D | G | I | H | A | R | L | N | S | R | V | T | R | G | K | L | T | A | E | T | C | E | R | T | L | K | R | L | I | P | V | T | D | I | . |
Query Conservation |   |
|   |   |   |
|   |   |
|   |
|
|
|
|
|   |
|
|   |   |
|
|   |   |   |
|   |   |
|   |   |
|   |
|   |
|   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
| . |
Template Conservation |   |
|   |   |   |   |   |
|
|   |
|
|
|
|
|   |
|
|   |   |
|
|   |   |
|   |   |   |
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |
|   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |
|   |   |   |   |   |   |   |   |
Template Sequence |   |
I | T | P | T | D | K | K | I | G | F | L | G | L | G | L | M | G | S | G | I | V | S | N | L | L | K | M | G | H | T | V | T | V | W | N | R | T | A | E | K | C | D | L | F | I | Q | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
E | G | A | R | L | G | R | T | P | A |
Template Known Secondary structure |   |
|
|
|
| S | S |  |  |  |  |  |
|
| S |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |
| S | S | G | G | G | G |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | T | T |
|  |  |
| S |
|  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|  |  |  |
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
263 | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | 310 | . | . | . | . | . | . | . | . |
  |
  |   |
80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | |
|
. | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | |
|
. | . | . | . | . | . | 130 | . | . | . | |
. | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  | . | . |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
| . | . |
|  |  |  |  |  |  |  |
|
| . |
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
H | A | L | A | A | A | D | L | V | I | E | A | A | S | E | R | L | E | V | K | K | A | L | F | A | Q | . |
. |
L | A | E | V | C | P | P | Q | T | L | L | T | T | N | T | S | S | I | . |
. |
S | I | T | A | I | A | A | E | I | K | . |
N | P | E | R | V | A | G | L | H | F | F | N | P | A | P | V | M | K | L | V | E |
Query Conservation |   |
  |   |
|   |   |
|
|
|
|
|
|
|
|   |
|   |
|   |   |
|   |   |
|   |   |   | . | . |
|   |   |   |   |   |   |   |   |
|
|
|
|
|
|
|
|
| . | . |   |
|   |   |
|
|   |   |   |   | . |   |
|   |
|   |   |
|   |
|
|
|   |
|   |   |   |   |   |
|
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
E | V | V | S | T | C | D | I | T | F | A | C | V | S | D | P | K | A | A | K | D | L | V | L | G | P | S | G | V | L | Q | G | I | R | P | G | K | C | Y | V | D | M | S | T | V | D | A | D | T | V | T | E | L | A | Q | V | I | V | S | R | G | G | R | F | L | E | A | P | V | S | G | N | Q | Q | L | S | N | D | G | M |
Template Known Secondary structure |   |
 |  |  |  |  |
| S |  |  |  |  |
|
| S | S |  |  |  |  |  |  |  |  |  | S | T | T |
| G | G | G | G |
|
| T | T |
|  |  |  |  |
| S |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |
|
|  |  | S |
|  |  |  |  |  |  | T |
|
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
319 | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . |
  |
  |   |
155 | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
. | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | V | S | G | L | A | T | A | A | E | V | V | E | Q | L | C | E | L | T | L | S | W | G | K | Q | P | V | R | C | H | S | T | P | G | F | I | V | N | R | V | A | R | P | . |
. |
. |
. |
. |
. |
. |
. |
Y | Y | S | E | A | W | R | A | L | E | E | Q | V | A | A | P | E | V | I | D | A | A | L | R | D | G | A | G | F |
Query Conservation |   |
|
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |
|
|   |
|   |
|   |
|
|
|
|   |
|
|
|   |   |   | . | . | . | . | . | . | . | . |   |   |   |
|
|   |   |
|   |   |
|
|   |
|   |   |   |   |
|
|   |
|   |   |   |   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
L | V | I | L | A | A | G | D | R | G | L | Y | E | D | C | S | S | C | F | Q | A | M | G | K | T | S | F | F | L | G | E | V | G | N | A | A | K | M | M | L | I | V | N | M | V | Q | G | S | F | M | A | T | I | A | E | G | L | T | L | A | Q | V | T | G | Q | S | Q | Q | T | L | L | D | I | L | N | Q | G | Q | L | A |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |
|  |  |  |  |  |  | T |  |  |  |  |  |  |  |  |  |  |  |  |  |
| S | S | T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |  |  |  |  |  |  |  |  | S | T | T |
|
Template Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
399 | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . |
  |
  |   |
227 | . | . | 230 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
. | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |
|
|
|
|
|  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
P | M | G | P | L | E | L | T | D | L | I | . |
. |
. |
. |
. |
. |
. |
. |
. |
G | Q | D | V | N | F | A | V | T | C | S | V | F | N | A | F | W | Q | E | R | R | F | L | P | S | L | V | Q | Q | E | L | V | I | G | G | R | L | G | K | K | S | G | L | G | V | Y | D | W |
Query Conservation |   |
  |   |
|
|
|   |
|   |
|   |
| . | . | . | . | . | . | . | . | . |
|
|
|   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |
|
|   |
|
|
|   |
|
|
|   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |
|   | . | . |   |   |
|   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |
Template Sequence |   |
S | I | F | L | D | Q | K | C | Q | N | I | L | Q | G | N | F | K | P | D | F | Y | L | K | Y | I | Q | K | D | L | R | L | A | I | A | L | G | D | . |
. |
A | V | N | H | P | T | P | M | A | A | A | A | N | E | V | Y | K | R | A | K | A | L | D | Q | S | D | N | D | M |
Template Known Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  | T |
|
|
|
| S | S | B |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . |  | T | T |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| T | T | S | B | G |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |
|  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
479 | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | |
|
. | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . |
  |