|   |
205 | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | |
|
. | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | |
. |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
| . | . |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| . |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
Query Sequence |   |
E | E | L | N | K | R | D | A | Y | D | V | L | I | V | G | S | G | P | A | G | A | A | A | A | I | Y | S | A | R | K | G | I | R | T | G | L | M | G | E | . |
. |
R | F | G | G | Q | I | L | D | T | V | D | I | E | N | Y | I | S | V | P | K | T | E | G | Q | K | L | A | G | A | L | K | V | H | V | D | E | Y | . |
D |
Query Conservation |   |
  |   |   |   |   |   |   |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
|
|
|   |
|   |
|
|   |
|
|
|
| . | . |   |   |
|
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |
|   |   |   |   |   |   |   | . |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
Template Conservation |   |
  |   |   |   |
|   |   |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
|
|   |   |
|   |   |
|
|
|
|
|
|   |   |   |
|
|
|   |   |   |   |
|   |   |   |
|   |   |   |   |   |   | . | . | . | . | . |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|
Template Sequence |   |
R | I | R | A | K | E | S | D | A | R | V | L | V | V | G | A | G | P | S | G | L | E | A | A | R | A | L | G | V | R | G | Y | D | V | V | L | A | E | A | G | R | D | L | G | G | R | V | T | Q | E | S | A | L | P | G | L | S | A | W | G | . |
. |
. |
. |
. |
R | V | K | E | Y | R | E | A | V | L | A | E | L | P | N |
Template Known Secondary structure |   |
|
|
|
|
| S | S |
|
|  |  |  |  |  |
|
| S |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|  |  |  |  |  |
| S | S | S | S | S |
| T |  |  |  |  |  |  | T | S | T | T |
| G | G | G | G | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  | T |
| T | T |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|  |  | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
384 | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | |
|
|
|
|
. | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . |
  |
  |   |
282 | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | |
|
|
|
|
|
. | . | . | . | 350 | . | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|  |  |
|
| . | . | . | . | . | . |  |  |  |  |
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | D | V | I | D | S | Q | S | A | S | K | L | I | P | A | A | V | E | G | G | L | H | Q | I | E | T | A | S | G | A | V | L | K | A | R | S | I | I | V | A | T | G | A | K | W | R | N | M | N | V | P | G | E | D | Q | Y | R | T | K | G | V | T | Y | C | . |
. |
. |
. |
. |
. |
P | H | C | D | G | P | L | F | K | G |
Query Conservation |   |
|   |
|   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |
|   |
|   |   |
|
|
|
|
|
|   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|   |
|
|
|
|
|
|   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|
Template Sequence |   |
V | E | I | Y | R | E | S | P | M | T | G | D | D | I | V | E | F | G | F | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
E | H | V | I | T | A | T | G | A | T | W | R | T | D | G | V | A | R | F | H | T | T | A | L | P | I | A | E | G | M | Q | V | L | G | P | D | D | L | F | A | G | R | L | P | D | G |
Template Known Secondary structure |   |
 |  |  |  | S | S |
|
|
|
|  |  |  |  |  |  | T | T |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|  |  |  |  |
|
|
|  |  |  |
| S | S |
|
| S | S | S |
| S | S |
|
|
| B |
| T | T | S |
|  |  |
|  |  |  |  |  |  | T |
|
|
| S | S |
Template Predicted Secondary structure |   |
|  |  |  |
|
|  |  |  |  |  |  |  |
|  |  |  |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
459 | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . |
  |
  |   |
356 | . | . | . | 360 | . | . | . | |
|
. | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | |
|
|
|
|
|
. | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |
|
| . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
| . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
K | R | V | A | V | I | G | G | . |
. |
G | N | S | G | V | E | A | A | I | D | L | A | G | I | V | E | H | V | T | L | L | E | F | A | P | E | M | K | A | D | . |
. |
. |
. |
. |
. |
Q | V | L | Q | D | K | L | R | S | L | K | N | V | D | I | I | L | N | A | Q | T | T | E | V | K | G | D | G | S | K | V | V | G | L |
Query Conservation |   |
|   |
|   |
|
|
|
| . | . |
|   |   |   |   |   |   |
|   |   |
|   |   |   |
|   |   |
|   |
|
|   |   |   |   |   |
|   |   |   | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |   |   |   |
|   |
|
|   |   |   |   |   |   |
|   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
Template Conservation |   |
  |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|
|   |
|   |   |   |   |   |
|   |   |
|   |   |   | . | . | . | . | . |
|
|
Template Sequence |   |
K | K | V | V | V | Y | D | D | D | H | Y | Y | L | G | G | V | V | A | E | L | L | A | Q | K | G | Y | E | V | S | I | V | T | P | G | A | Q | V | S | S | W | T | N | N | T | F | E | V | N | R | I | Q | R | R | L | I | E | N | G | V | A | R | V | T | D | H | A | V | V | A | V | G | A | G | . |
. |
. |
. |
. |
G | V |
Template Known Secondary structure |   |
S |  |  |  |  |  |  |
| S |
| S | S |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |  | S | S | S | S | T | T | G | G | G | G | T | T | T |
|  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  | S |  |  |  |  |  |  |  | T | T | . | . | . | . | . |  |  |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |
|
| . | . | . | . | . |
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
524 | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | |
|
|
|
|
. | . |
  |
  |   |
428 | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |
|
|  |  |  |
|  |  |  |  |  |
|
|
|  |  |
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | Y | R | D | R | V | S | G | D | I | H | N | I | E | L | A | G | I | F | V | Q | I | G | L | L | P | N | T | N | W | L | E | G | A | V | E | R | N | R | M | G | E | I | I | I | D | A | K | C | E | T | N | V | K | G | V | F | A | A | G | D | C | T | T | V | P | Y | K | Q | I | I | I | A | T | G | E | G | A | K | A |
Query Conservation |   |
  |   |   |   |   |   |   |
|   |   |   |   |
|   |   |
|   |
|
|   |
|   |
|   |   |
|
|   |   |
|
|   |   |
|
|   |   |   |   |   |
|   |
|   |
|
|   |   |   |   |
|
|   |
|
|
|
|
|
|
|
|   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |   |   |   |   |
|   |   |   |   |
|   |
|
|   |
|
|   |
|   |
|   |   |
|   |   |   |
|   |   |   | . | . | . | . | . | . | . | . | . | . |
|   |   |   |   |   |   |   |   |   |
|   |
|   |
|
|
|
|
|   |   |   | . | . |   |   |
|   |   |
|
|   |   |
|   |   |
|
Template Sequence |   |
T | V | R | D | T | Y | A | S | I | E | R | E | L | E | C | D | A | V | V | M | V | T | A | R | L | P | R | E | E | L | Y | L | D | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
L | V | A | R | R | D | A | G | E | I | A | S | V | R | G | I | G | D | A | W | A | P | . |
. |
G | T | I | A | A | A | V | W | S | G | R | R | A |
Template Known Secondary structure |   |
 |  |  |  | T | T | T |
|
|  |  |  |  |  |
| S |  |  |  |  |  |
|
|  |  |  |
|
|  |  |  |  |  | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  | T | T | T | S |
| S |  |  |  |  |
| G | G | G | T | S |
| . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |
|
|  |  |  |
|  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
| . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
599 | 600 | . | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | |
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | 640 | . | . | . | . | . | . | . | . | . | 650 | . | . | . | |
|
. | . | . | . | . | . | 660 | . | . | . | . | . | . |
  |
  |   |
508 | . | 510 | . |
Predicted Secondary structure |   |
 |  |  |  |
Query SS confidence |   |
|
|
|
|
Query Sequence |   |
S | L | S | A |
Query Conservation |   |
|   |   |
|
Alig confidence |   |
|
|
|
|
Template Conservation |   |
|   |   |
|
Template Sequence |   |
A | E | E | F |
Template Known Secondary structure |   |
 |  |  | T |
Template Predicted Secondary structure |   |
 |  |  |  |
Template SS confidence |   |
|
|
|
|
  |   |
667 | . | . | 670 |
  |