|   |
196 | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | |
|
|
|
|
|
|
. | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | |
|
. | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
| . | . |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
D | T | G | A | E | K | R | A | A | E | E | L | N | K | R | D | A | Y | D | . |
. |
. |
. |
. |
. |
. |
V | L | I | V | G | S | G | P | A | G | A | A | A | A | I | Y | S | A | R | K | G | I | R | T | G | L | M | G | E | . |
. |
R | F | G | G | Q | I | L | D | T | V | D | I | E | N | Y | I | S | V | P | K | T | E | G |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
|
|
|   |
|   |
|
|   |
|
|
|
| . | . |   |   |
|
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
|
|
|   |
|   |   |
|   |
|
|
|   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   | . | . | . | . |   |   |   |   |   |   |
Template Sequence |   |
T | L | L | S | G | L | G | V | L | D | P | S | E | D | P | A | Y | Y | D | H | V | H | V | H | T | D | V | L | V | V | G | A | G | P | A | G | L | A | A | A | R | E | A | S | R | S | G | A | R | V | M | L | L | D | E | R | P | E | A | G | G | T | L | R | E | A | S | G | E | Q | . |
. |
. |
. |
I | D | G | I | D | A |
Template Known Secondary structure |   |
 |  |
| S | S |
|
|
|
|
| S | S |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| S |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |  |  |
| S | S | S | S | S |
| G | G | G | G | G |
|
| S |
|  | . | . | . | . |  | T | T |  |  |  |
Template Predicted Secondary structure |   |
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
104 | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | |
|
|
|
. | . | . | . | . | . |
  |
  |   |
267 | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | |
. | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | |
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . |
|  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Q | K | L | A | G | A | L | K | V | H | V | D | E | Y | D | . |
V | D | V | I | D | S | Q | S | A | S | K | L | I | P | A | A | V | E | G | G | L | H | Q | I | E | T | A | S | G | A | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
V | L | K | A | R | S | I | I | V | A | T | G | A | K | W | R | N | M | N | V | P | G |
Query Conservation |   |
  |
|
|   |   |   |
|   |   |   |   |   |   |   |   | . |
|   |
|   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   | . | . | . | . | . | . | . | . | . | . | . | . |   |
|   |
|   |   |
|
|
|
|
|
|   |   |   |   |   |   |   |
|   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |
|
|
|
|
|
|
|   |
|
|   |
|   |   |   |
|
Template Sequence |   |
A | Q | W | I | D | A | V | T | E | E | L | A | A | A | E | E | T | T | H | L | Q | R | T | T | V | F | G | S | Y | D | A | N | Y | I | L | A | A | Q | R | R | T | V | H | L | D | G | P | S | G | Q | G | V | S | R | E | R | I | W | H | I | R | A | K | Q | V | V | L | A | T | A | A | H | E | R | P | I | V | F | E | N |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |
| T | T |  |  |  |  | S | S |  |  |  |  |  |  |  | T | T | T |  |  |  |  |  |  |  |
| S | T | T |
| S | S |
|
|
| T | T |
|
| S |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|
|
|
| B | T |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . |
  |
  |   |
334 | . | . | |
|
. | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . |
Predicted Secondary structure |   |
 |  |  | . | . |
|
|
|
|
|  |  |
|
|  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
Query SS confidence |   |
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | D | Q | . |
. |
Y | R | T | K | G | V | T | Y | C | P | H | C | D | G | P | L | F | K | G | K | R | V | A | V | I | G | G | G | N | S | G | V | E | A | A | I | D | L | A | G | I | V | E | H | V | T | L | L | E | F | A | P | E | M | K | A | D | Q | V | L | Q | D | K | L | R | S | L | K | N | V | D | I | I | L | N |
Query Conservation |   |
  |   |   | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |
|
|
|
|
|   |   |   |   |   |   |
|   |   |
|   |   |   |
|   |   |
|   |
|
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |   |
Alig confidence |   |
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|
|
|
|
|   |   |
|   |   |   |   |   |
|
|   |   |   |
|   |   |   |
|   |
|
|
|
|   |
|
|
|   |   |
|   |   |   |
|   |   |
|   |   |   |
|   |   |
|   |
|
|
|   |   |   |   |   |   |   | . | . | . | . |   |   |   |   |   |   |   |   |
|
|   |
|   |   |
|
Template Sequence |   |
N | D | R | P | G | I | M | L | A | G | S | V | R | S | Y | L | N | R | F | G | V | R | A | G | S | K | I | A | V | A | T | T | N | D | S | V | Y | P | L | V | S | E | L | A | A | S | G | G | V | V | A | V | I | D | A | R | Q | N | I | S | A | . |
. |
. |
. |
A | A | A | Q | A | V | T | D | G | V | T | V | L | T | G |
Template Known Secondary structure |   |
T | T | S | T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  |  | S |
| S | S |  |  |  |  |  | S | S | G | G | G |  |  |  |  |  |  |  | G | G | G | T |
|
| S |  |  |  |  |
| S | S | S |
|
|  | . | . | . | . |  |  |  |  |  |  |  | T | T |
|
|  |  | T | T |
Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  | . | . | . | . |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | |
|
|
|
. | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . |
  |
  |   |
412 | . | . | . | . | . | . | . | 420 | |
. | . | . | . | . | . | . | . | . | 430 | . | . | |
|
|
|
. | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | |
. | 460 | . | . | . | . | |
|
|
|
. | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |  |
| . |
|
|  |  |  |  |  |  |  |  |  |
| . | . | . | . |
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |
|
|  |  |  |
|  |  |  |  | . |  |
|
|
|  |  | . | . | . | . |
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | Q | T | T | E | V | K | G | D | . |
G | S | K | V | V | G | L | E | Y | R | D | R | . |
. |
. |
. |
V | S | G | D | I | H | N | I | E | L | A | G | I | F | V | Q | I | G | L | L | P | N | T | N | W | L | . |
E | G | A | V | E | R | . |
. |
. |
. |
N | R | M | G | E | I | I | I | D | A | K | C | E | T | N | V | K |
Query Conservation |   |
  |   |
|   |
|
|   |   |   | . |   |   |   |
|   |   |
|   |   |   |   |   | . | . | . | . |   |   |
|   |   |   |   |
|   |   |
|   |
|
|   |
|   |
|   |   |
|
|   |   |
|
| . |   |   |
|
|   |   | . | . | . | . |   |   |   |
|   |
|   |
|
|   |   |   |   |
|
|   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
Template Conservation |   |
  |   |
|   |   |
|   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |
|
|   |
|
|
|
|   |
|   |   |
|   |   |   |
|   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |
| . | . | . | . | . |   |
|
|   |
|
Template Sequence |   |
S | V | V | A | N | T | E | A | D | A | S | G | E | L | S | A | V | L | V | A | T | L | D | E | Q | R | N | L | G | E | A | Q | R | F | E | A | D | V | L | A | V | S | G | G | F | N | P | V | V | H | L | H | S | Q | R | Q | G | K | L | N | W | D | T | S | I | H | A | F | V | P | . |
. |
. |
. |
. |
A | D | A | V | A |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |
| T | T | S | S |  |  |  |  |  |  |  |  | B |
| T | T |
|
| B |
|
|
|  |  |  |  |
| S |  |  |  |  |  |
|
|  |  |  |
|
|  |  |  |  |  | T | T |
|
|  |  |  |  | T | T | T | T |  |  |  |  | . | . | . | . | . |
| S |
|
| T |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
336 | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | |
|
|
|
|
. | . | . | . | 410 |
  |
  |   |
482 | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . |
Predicted Secondary structure |   |
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | V | F | A | A | G | D | C | T | T | V | P | Y | K | Q | I | I | I | A | T | G | E | G | A | K | A | S | L | S | A | F | D | Y | L | I | R | T | K | T | A |
Query Conservation |   |
|
|
|
|
|
|
|   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|   |   |
|
|   |   |
|   |   |   |
|   |
|   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|
|   |
|
|
|   |   |
|   | . | . |   |   |   |   |   |
|   |
|   |
|   |   |
|
|   |   |
|
|   |   |
|
|   |   |   |   |   |
Template Sequence |   |
N | Q | H | L | A | G | A | L | T | G | L | . |
. |
L | D | T | A | S | A | L | S | T | G | A | A | T | G | A | A | A | A | S | A | A | G | F | E | K | I | A |
Template Known Secondary structure |   |
T |  |  |  |
| G | G | G | G | T |
| . | . |
| S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
|
|
|
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |
|
|
|
| . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
411 | . | . | . | . | . | . | . | . | 420 | . | |
|
. | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . |
  |