|   |
205 | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | |
|
. | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | |
|
|
|
|
|
|
|
|
|
|
|
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
| . | . |
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Sequence |   |
E | E | L | N | K | R | D | A | Y | D | V | L | I | V | G | S | G | P | A | G | A | A | A | A | I | Y | S | A | R | K | . |
. |
G | I | R | T | G | L | M | G | E | R | F | G | G | Q | I | L | D | T | V | D | I | E | N | Y | I | S | V | P | K | T | E | G | Q | K | L | A | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Conservation |   |
  |   |   |   |   |   |   |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
|
|
|   | . | . |
|   |
|
|   |
|
|
|
|   |   |
|
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|   | . | . | . | . | . | . | . | . | . | . | . | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |   |   |   |   |
|   |   |   |   |
|
|
|
|
|
|
|   |
|
|
|   |
|
|   |   |
|   |   |   |   |   |
|   |   |
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
P | Q | I | R | A | P | S | H | V | P | F | L | L | I | G | G | G | T | A | A | F | A | A | A | R | S | I | R | A | R | D | P | G | A | R | V | L | I | V | S | E | D | P | E | L | P | Y | M | R | P | P | L | S | K | E | L | W | F | S | D | D | P | N | V | T | K | T | L | Q | F | R | Q | W | N | G | K | E | R | S | I |
Template Known Secondary structure |   |
|
|
|
|
|
|  |  |  |  |  |  |  |  | S |
| S |  |  |  |  |  |  |  |  |  |  |  |  |  | S | T | T |
|  |  |  |  |  |  | S | S | S | S |
|
| B |
| S | G | G | G | G | T | G | G | G | S |
|
|
| T | T |  |  |  |  |
|  |  |  |
| T | T | S |
|  |  |  | S |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
123 | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . |
  |
  |   |
|
|
|
|
|
|
|
|
|
|
271 | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | |
|
|
|
|
Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  | . | . | . | . | . |
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
G | A | L | K | V | H | V | D | E | Y | D | V | D | V | I | D | S | Q | S | A | S | K | L | I | P | A | A | V | E | G | G | L | H | Q | I | E | T | A | S | G | A | V | L | K | A | R | S | I | I | V | A | T | G | A | K | W | R | N | M | N | V | P | G | E | D | . |
. |
. |
. |
. |
Query Conservation |   |
. | . | . | . | . | . | . | . | . | . |   |   |
|   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |
|   |
|   |   |
|
|
|
|
|
|   |   |   |   |   |   |   |
|   |
|   |   | . | . | . | . | . |
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |
|   |   |
|   |   |
|
|   | . | . | . | . | . |   |   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |
|
|
|
|
|
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
Template Sequence |   |
Y | F | Q | P | P | S | F | Y | V | S | A | Q | D | L | P | N | I | E | N | G | G | V | A | V | L | T | G | K | K | V | V | H | L | D | V | . |
. |
. |
. |
. |
R | G | N | M | V | K | L | N | D | G | S | Q | I | T | F | E | K | C | L | I | A | T | G | G | T | P | R | S | L | S | A | I | D | R | A | G | A | E | V | K |
Template Known Secondary structure |   |
B | S | S |
| G | G | G |
| B |
| G | G | G | G | G | G | S | T | T |
|  |  |  |  |  |  | S |
|
|  |  |  |  |  | T | . | . | . | . | . | T | T | T |  |  |  |  | T | T | S |
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|
|  |  |  |  | T | S |
|  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|  |  |  |  |  |
|
| . | . | . | . | . |
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
203 | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | |
|
|
|
|
. | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . |
  |
  |   |
|
|
336 | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | |
|
|
|
380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | |
|
|
|
|
|
. | . | . | . | . | . | 400 | . | . | . |
Predicted Secondary structure |   |
. | . |  |
|
|
|
|
|  |  |
|
|  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| . | . | . | . |
|  |  |  |  |  |
|
|
|
|
|
|
|
| . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
Q | Y | R | T | K | G | V | T | Y | C | P | H | C | D | G | P | L | F | K | G | K | R | V | A | V | I | G | G | G | N | S | G | V | E | A | A | I | D | L | A | G | I | V | E | . |
. |
. |
. |
H | V | T | L | L | E | F | A | P | E | M | K | A | D | . |
. |
. |
. |
. |
. |
Q | V | L | Q | D | K | L | R | S | L |
Query Conservation |   |
. | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |
|
|
|
|
|   |   |   |   |   |   |
|   |   |
|   |   |   |
|   | . | . | . | . |   |
|   |
|
|   |   |   |   |   |
|   |   |   | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
. | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|   |
|   |   |
|   |
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
Template Sequence |   |
S | R | T | T | L | F | R | K | I | G | D | F | R | A | L | E | K | I | S | R | E | V | K | S | I | T | V | I | G | G | G | F | L | G | S | E | L | A | C | A | L | G | R | K | S | Q | A | S | G | I | E | V | I | Q | L | F | P | E | K | G | N | M | G | K | I | L | P | Q | Y | L | S | N | W | T | M | E | K | V | K | R |
Template Known Secondary structure |   |
T | T |  |  |  |
|
| S |  |  |  |  |  |  |  |  |  |  |  | T | T |
| S |  |  |  |  |  |
|
| S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |
| S | S | S | S | T | T | T | T | T | S |
|  |  |  |  |  |  |  |  |  |  |  |  | T |
Template Predicted Secondary structure |   |
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
278 | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . |
  |
  |   |
404 | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | |
460 | . | . | . | . | . | . | . | |
. | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |
|
|  |  |  |
|  |  |  |  |  | . |
|
|
|  |  |
|
|
| . |
|
|  |  |  |
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
K | N | V | D | I | I | L | N | A | Q | T | T | E | V | K | G | D | G | S | K | V | V | G | L | E | Y | R | D | R | V | S | G | D | I | H | N | I | E | L | A | G | I | F | V | Q | I | G | L | L | P | N | T | N | W | L | E | . |
G | A | V | E | R | N | R | M | . |
G | E | I | I | I | D | A | K | C | E | T | N | V | K |
Query Conservation |   |
  |
|
|   |
|   |   |   |   |   |
|   |
|
|   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |
|   |
|
|   |
|   |
|   |   |
|
|   |   |
|
|   | . |   |
|
|   |   |   |   |   | . |
|   |
|   |
|
|   |   |   |   |
|
|   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
Template Conservation |   |
  |
|
|   |
|   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   | . | . | . | . | . | . |
|   |   |   |   |
|   |   |
|   |
|
|   |
|
|   |
|   |
|   |   |
|
|   |   |
|
|   |   |   |
|
|   |   |
|   |   |   |
|   |
|   |
|
|   |   |
|   |
|   | . |   |
Template Sequence |   |
E | G | V | K | V | M | P | N | A | I | V | Q | S | V | G | V | S | G | G | R | L | L | . |
. |
. |
. |
. |
. |
I | K | L | K | D | G | R | K | V | E | T | D | H | I | V | T | A | V | G | L | E | P | N | V | E | L | A | K | T | G | G | L | E | I | D | S | D | F | G | G | F | R | V | N | A | E | L | Q | A | R | . |
S |
Template Known Secondary structure |   |
T | T |
|  |  |  |
| S |
|
|  |  |  |  |  |  |  | T | T |  |  |  | . | . | . | . | . | . |  |  |  | T | T | S |
|  |  |  |  | S |  |  |  |  |
|
|
|  |  |  |
|
| T |  |  |  |  | T | T |
|
| B |
| T | T | T |
| S |  |  |
|
| T | T | S |  |  |  | . | T |
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|  |  |  | . | . | . | . | . | . |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|  |  |  |
| . |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
358 | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | |
430 |
  |
  |   |
482 | . | . | . | . | . | . | . | 490 | |
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . |
Predicted Secondary structure |   |
|  |  |  |  |  |
|
|
| . | . | . | . | . | . | . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | V | F | A | A | G | D | C | T | . |
. |
. |
. |
. |
. |
. |
. |
T | V | P | Y | K | Q | I | I | I | A | T | G | E | G | A | K | A | S | L | S | A |
Query Conservation |   |
|
|
|
|
|
|
|   |   | . | . | . | . | . | . | . | . |   |   |   |   |   |   |
|   |   |
|   |   |   |
|   |   |
|
|   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|
|
|
|
|
|   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |
|   |
Template Sequence |   |
N | I | W | V | A | G | D | A | A | C | F | Y | D | I | K | L | G | R | R | R | V | E | H | H | D | H | A | V | V | S | G | R | L | A | G | E | N | M |
Template Known Secondary structure |   |
T |  |  |  |
| G | G | G |  |  |  |  |  | T | T | T |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
431 | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . |
  |