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Job DescriptionP21151
Confidence100.00%DateThu Jan 5 11:37:50 GMT 2012
Rank39Aligned Residues277
% Identity20%Templatec3hhdC_
PDB info PDB header:transferase, hydrolaseChain: C: PDB Molecule:fatty acid synthase; PDBTitle: structure of the human fatty acid synthase ks-mat didomain2 as a framework for inhibitor design.
Resolution2.15 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   14.....20.........30.........40.........50. ........60....... ..70.
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Query Sequence  MGRSKGGAFRNVRAEDLSAHLMRSLLARNPALEAAALD. . . . DIYWGCVQQTLEQGFN. . . . . . . . . . . . . . . . . . IARN
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Template Sequence  FGVHPKQAHTMDPQLRLLLEVTYEAIV. DGGINPDSLRGTHTGVWVGVSGSETSEALSRDPETLVGYSMVGCQRAMMANR
Template Known Secondary structure  TT

TS
.TT

GGGGTTS




TS
TTT

TSTT
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   65....70.........80.........90. ........100.........110.........120.........130.........140...
 
   72.......80.........90.........100.........110.........120.........130.........140.........150.
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Query Sequence  AALLAEVPHSVPAVTVNRLCGSSMQALHDAARMIMTGDAQACLVGGVEHMGHVPMSHGVDFHPGLSRNVAKAAGMMGLTA
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Template Sequence  LSFFFDFRG. . PSIALDTACSSSLMALQNAYQAIHSGQCPAAIVGGINVLLKPNTSVQFLRLGMLSPEG. . . . . . . . . . .
Template Known Secondary structure  T

S..


GGGTTS
S



T
B
TTS...........
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   144.....150.. .......160.........170.........180.........190.........200.........210
 
   152.......160.........170.........180.........190.........200.........210.........220.........230.
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Query Sequence  EMLARMHGISREMQDAFAARSHARAWAATQSAAFKNEIIPTGGHDADGVLKQFNYDEVIRPETTVEALATLRPAFDPVNG
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Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . TCKAFDTAGNG
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TTBTT


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   211........220.
 
   232.......240.........250.........260.........270...... ...280.........290.........300.....
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Query Sequence  MVTAGTSSALSDGAAAMLVMSESRAHELGLKPRARVRSMAVVGCD. . . . . . PSIMGYGPVPASKLALKKAGLSASDIGVF
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Template Sequence  YC. . . . . . . RSEGVVAVLLTKKSLA. . . . RRVYATILNAGTNTDGFKEQGVTFPSGDIQEQLIRSLYQSAGVAPESFEYI
Template Known Secondary structure  B
.......BB
GGG
....SS
S



TT
TTS

T

GGG
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   222. ......230......... 240.........250.........260.........270.........280.........290
 
   306...310.. .......320.........330.........340.........350.........360...
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Query Sequence  EMNEAFA. . . . AQILPCIKDLGLIEQIDEKINLNGGAIALGHPLGCSGARISTTLLNLMERK. . . . . . . . . . . . . . . . . .
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Template Sequence  EAHGTGTKVGDPQELNGITRA. LCATRQEPLLIGSTKSNMGHPEPASGLAALAKVLLSLEHGLWAPNLHFHSPNPEIPAL
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TT.SSS
SS

T
B
GGGTB



SS

SB
TT
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   291........300.........310. ........320.........330.........340.........350.........360.........
 
   364.....370.........380.....
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Query Sequence  . . . . . . . . . . . . . . DVQFGLATMCIGLGQGIATVFE
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Template Sequence  LDGRLQVVDQPLPVRGGNVGINSFGFGGSNVHIILR
Template Known Secondary structure  TS

S

B

S

TTS
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   370.........380.........390.........400.....
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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