|   |
6 | . | . | . | 10 | . | . | . | . | |
. | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |  |
| . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
Query Sequence |   |
H | R | I | T | L | L | F | N | A | . |
N | K | A | Y | D | R | Q | V | V | E | G | V | G | E | Y | L | Q | A | S | Q | S | E | W | D | I | F | I | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
E | E | D |
Query Conservation |   |
  |   |
|
|
|
|
|   |   | . |   |   |   |   |   |   |   |
|
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
Template Conservation |   |
|
|
|
|
|
|   |
|
|
|   |
|
|
|   |
|
|   |
|   |   |
|
|   |   |
|   |   |   |
|   |   |
|   |
|   |   |   |
|   |   |
|
|   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |
|
|
|   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |
Template Sequence |   |
K | R | I | G | I | L | T | S | G | G | D | A | P | G | M | N | A | A | V | R | A | V | T | R | V | A | I | A | N | G | L | E | V | F | G | I | R | Y | G | F | A | G | L | V | A | G | D | I | F | P | L | E | S | E | D | V | A | H | L | I | N | V | S | G | T | F | L | Y | S | A | R | Y | P | E | F | A | E | E | E | G |
Template Known Secondary structure |   |
|  |  |  |  |  |  |
| S | S |
|
| T | T |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T |
|  |  |  |  |  |
| T |  |  |  |  |  |  |  | T |
|  |  |  |
|
| G | G | G | G | T | T |
| T | T |
|
| S |
| T | T |
|
|
|
|
| G | G | G | T | S |  |  |  |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|  |  |  |
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
2 | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . |
  |
  |   |
45 | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | |
|
70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | |
|
. | . | . | 120 |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|  |  |  | . | . |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|  |  |  |
|
|  |  |  |  |  |  |  |  | . | . |  |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
Query Sequence |   |
F | R | A | R | I | D | K | I | K | D | W | L | G | D | G | V | I | A | D | F | D | D | K | Q | I | . |
. |
E | Q | A | L | A | D | V | D | V | P | I | V | G | V | G | G | S | Y | H | L | A | E | S | Y | P | P | V | H | Y | I | A | T | D | N | Y | A | L | V | E | S | A | F | L | H | L | K | E | . |
. |
K | G | V | N |
Query Conservation |   |
  |   |   |   |
|   |   |   |   |   |   |   |   |
|
|
|
|   |   |   |   |   |   |   |   | . | . |   |   |   |
|   |   |   |   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |
|   |   |   |
|   |   | . | . |   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |
|   |   |   |   |
|
|   |
|
|
|
|
|
|   |
|
|   |   |   |
|   |   |
|   |   |   |   |
|   |
|
|
|
|
|
|
|
|
|
|
|
|   |   |
|
|   |
|   |
|
|   |
|
|   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|   |
|   |   |
Template Sequence |   |
Q | L | A | G | I | E | Q | L | K | K | H | G | I | D | A | V | V | V | I | G | G | D | G | S | Y | H | G | A | L | Q | L | T | R | H | G | F | N | S | I | G | L | P | G | T | I | D | N | D | I | P | Y | T | D | A | T | I | G | Y | D | T | A | C | M | T | A | M | D | A | I | D | K | I | R | D | T | A | S | S | H | H |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |  |  |  |  |  | T | T |
|
|
| T | T |
| S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
82 | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . |
  |
  |   |
121 | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | F | A | F | Y | G | L | P | E | S | S | G | K | R | W | A | T | E | R | E | Y | A | F | R | Q | L | V | A | E | E | K | Y | R | G | V | V | Y | Q | G | L | E | T | A | P | E | N | W | Q | H | A | Q | N | R | L | A | D | W | L | Q | T | L | P | P | Q | T | G | I | I | A | V | T | D | A | R | A | R | H | I | L | Q |
Query Conservation |   |
  |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |
|   |
|
|   |   |   |   |
|   |   |
|   |
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|   |
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|   |   |
|   |
|
|   |   |   |
|
|
|   |   |
|
|   |
|
|
|
|
|   | . |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |
|
|
|
|
|
|
|   |   |   |   |   |   |   |   |
Template Sequence |   |
R | V | F | I | V | N | V | M | G | . |
. |
. |
. |
. |
. |
. |
. |
. |
R | N | C | G | D | I | A | M | R | V | G | V | A | C | G | A | D | A | I | V | I | P | E | R | . |
P | Y | D | V | E | E | I | A | N | R | L | K | Q | A | Q | E | S | G | K | D | H | G | L | V | V | V | A | E | G | V | M | T | A | D | Q | F | M |
Template Known Secondary structure |   |
|  |  |  |  |  |  |
|
| . | . | . | . | . | . | . | . | . | T | T |
|
|  |  |  |  |  |  |  |  |  | T | T |
| S |  |  |  |
| T | T | S | . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
|  |  |  |  |  |  | T | T | T |
|
|  |  |  |  |  |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |
|
| . | . | . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
| . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
162 | . | . | . | . | . | . | . | 170 | |
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | |
. | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . |
  |
  |   |
201 | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | C | E | H | L | H | I | P | V | P | E | K | L | C | V | I | G | I | D | N | E | E | L | T | R | Y | L | S | R | V | A | L | S | S | V | A | Q | G | A | R | Q | M | G | Y | Q | A | A | K | L | L | H | R |
Query Conservation |   |
  |
|   |   |   |
|   |   |
|
|   |
|
|
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|
|   |   |   |   |   |   |   |
|   |   |
|
|   |   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |   |   |   |   |   |   |   |
|   |   |   |
|
|   | . | . | . | . | . |   |
|
|
|
|   |
|
|   |   | . |
|   |   |   |
|   |   |
|
|   |   |
|
|   |   |   |   |   |
Template Sequence |   |
A | E | L | K | K | Y | G | D | F | D | V | R | A | N | V | L | G | H | . |
. |
. |
. |
. |
M | Q | R | G | G | T | P | T | V | S | . |
D | R | V | L | A | S | K | L | G | S | E | A | V | H | L | L | L | E |
Template Known Secondary structure |   |
 |  |  |  |  | S | S |
|
|
|  |  |  |  |  |
| G | G | . | . | . | . | . | G | G | G |
| S |
|
|
|  |  | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|  |  | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
232 | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
250 | . | . | . | . | . | . | . | . | . | |
260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . |
  |