|   |
4 | . | . | . | . | . | 10 | . | . | |
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | |
|
|
|
|
|
. | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|  | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |
|
|  |  |  |  |
|
|
| . | . | . | . | . | . |
|
|
|
|  |  |
|
|
|  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
K | I | V | I | A | N | R | G | E | . |
. |
. |
. |
. |
. |
. |
. |
. |
I | A | L | R | I | L | R | A | C | K | E | L | G | I | K | T | V | A | V | H | S | S | A | D | R | D | L | K | H | V | L | L | A | D | E | T | V | C | I | G | P | . |
. |
. |
. |
. |
. |
A | P | S | V | K | S | Y | L | N | I | P | A | I | I | S |
Query Conservation |   |
|
|
|
|   |   |   |
|   | . | . | . | . | . | . | . | . | . |   |
|   |   |
|
|
|
|
|   |   |   |
|   |   |
|
|   |
|   |   |   |   |
|   |   |
|   |   |   |   |   |
|
|   |   |   |   |
|   |   | . | . | . | . | . | . |   |   |   |   |   |   |   |   |
|   |
|   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|   |
|
|   |
|
|   |   |   |
|   |   |
|
|
|   |
|
|   |   |
|   |   |
|
|   |   |   |
|   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
K | V | A | I | L | F | G | G | C | S | E | E | H | D | V | S | V | K | S | A | I | E | I | A | A | N | I | N | K | E | K | Y | E | P | L | Y | I | G | I | T | K | S | G | V | W | K | M | C | E | K | P | C | A | E | W | E | N | E | N | C | Y | S | A | V | L | S | P | D | K | K | M | H | G | L | L | V | K | K | N | H |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |
| S | S | T | T |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S |
| T | T | T |  |  |  |  |  |  |  |  |
| T | T | S |
|  |  |  |  | S | S |
| S | T | T |
|
|
| T | T |
|  |  |  |  |  |
|
|
| T | T | T |
|  |  |  |  |  | S | S | S |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
5 | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . |
  |
  |   |
69 | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | |
. | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
| . |
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | A | E | I | T | G | A | V | A | I | H | P | G | Y | G | F | L | S | . |
E | N | A | N | F | A | E | Q | V | E | R | S | G | F | I | F | I | G | P | K | A | E | T | I | R | L | M | G | D | K | V | S | A | I | A | A | M | K | K | A | G | V | P | C | V | P | G | S | D | G | P | L | G | D | D | M | D | K | N | R | A |
Query Conservation |   |
|
|   |   |   |   |   |
|   |
|
|
|   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |   |   |
|
|   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
Template Conservation |   |
  |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |
|   |   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |
|   | . | . | . | . | . |
Template Sequence |   |
E | Y | E | I | N | H | V | D | V | A | F | S | A | L | H | G | K | S | G | E | D | G | S | I | Q | G | L | F | E | L | S | G | I | P | F | V | G | C | D | I | Q | S | S | A | I | C | M | D | K | S | L | T | Y | I | V | A | K | N | A | G | I | A | T | P | A | F | W | V | I | N | K | D | D | R | P | . |
. |
. |
. |
. |
Template Known Secondary structure |   |
S |  |  |  |  |  |
| S |  |  |  |  |
|
|
| S | T | T | T | T | S | S |  |  |  |  |  |  |  |  |  | T |
|
| B | S | S |
|
|  |  |  |  |  |  |  |  | S |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
|
|
|  |  |  |  |
| S | S |
|
|
| . | . | . | . | . |
Template Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |
|
|
|  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
|
|  |  |  |  | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
85 | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
  |
  |   |
148 | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
I | A | K | R | I | G | Y | P | V | I | I | K | A | S | G | G | G | G | G | R | G | M | R | V | V | R | G | D | A | E | L | A | Q | S | I | S | M | T | R | A | E | A | K | A | A | F | S | N | D | M | V | Y | M | E | K | Y | L | E | N | P | R | H | V | E | I | Q | V | L | A | D | G | Q | G | N | A | I | Y | L | A | E |
Query Conservation |   |
  |   |   |   |   |   |   |
|   |
|
|
|
|   |   |
|   |
|   |   |
|
|   |   |
|   |   |   |   |
|
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |
|   |
|   |
|
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . |   |   |   |   |   |   |   |   |
|
|
|   |
|   |
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
V | A | A | T | F | T | Y | P | V | F | V | K | P | A | R | S | G | S | S | F | G | V | K | K | V | N | S | A | D | E | L | D | Y | A | I | E | S | A | . |
. |
. |
. |
. |
. |
R | Q | Y | D | S | K | I | L | I | E | Q | A | V | S | G | C | E | V | G | C | A | V | L | G | N | S | A | A | L | V | V | G | E | V | D | Q |
Template Known Secondary structure |   |
| G | G | G | S |
| S | S |  |  |  |  |  | S | S |
|
| T | T | T | T |
|  |  |  |
| S | G | G | G |  |  |  |  |  |  |  |  | . | . | . | . | . | . | T | T | T |
| S | S |  |  |  |  |  |
|
|
| S |  |  |  |  |  |  |  |  |  |
| T | T |
|
|  |  |
|
|
|  |  |
Template Predicted Secondary structure |   |
 |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | |
|
|
|
|
|
. | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . |
  |
  |   |
|
|
|
|
|
|
|
|
|
|
|
228 | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | |
. | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . |
Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  | . |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
R | D | C | S | M | Q | R | R | H | Q | K | V | V | E | E | A | P | A | P | G | I | T | P | E | L | R | R | Y | I | G | E | R | C | A | K | A | C | V | D | I | G | Y | R | G | A | G | T | F | E | F | L | F | E | . |
N | G | E | F | Y | F | I | E | M | N | T | R | I | Q | V |
Query Conservation |   |
. | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |
|
|   |   |
|   |   |   |
|
|
|   |   |   | . |   |   |   |   |   |
|
|
|
|
|
|
|
|   |
|
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   | . |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |
|
|   |   |
|   |   |   |
|
|   |   |   |   |   |   |
|   |   |   |
|
|
|
|
|   |   |
|
|   |
Template Sequence |   |
I | R | L | Q | Y | G | I | F | R | I | H | Q | E | V | E | P | E | K | G | S | E | N | A | V | I | T | V | P | A | . |
D | L | S | A | E | E | R | G | R | I | Q | E | T | V | K | K | I | Y | K | T | L | G | C | R | G | L | A | R | V | D | M | F | L | Q | D | R | G | R | I | V | L | N | E | V | N | T | L | P | G | F |
Template Known Secondary structure |   |
 |  |  | S | S | S |
|
|
| G | G | G | S | S | S | G | G | G |
|
| S | S |  |  |  |  | S | S |
| . | S | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |  |  |  |  |  |  |  |
| T | T |
|
|  |  |  |  |  |  |  | S | S |
|
|
|
Template Predicted Secondary structure |   |
 |  |
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
| . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
234 | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | |
. | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . |
  |
  |   |
296 | . | . | |
|
|
|
. | 300 | . | . | . | . | . | . | . | . | . | 310 | . | |
|
|
. | . | . | . | . | . |
Predicted Secondary structure |   |
|
|  | . | . | . | . |  |  |  |  |  |  |
|
|
|  |  |  |  | . | . | . |  |  |  |  |  |
|
Query SS confidence |   |
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
Query Sequence |   |
E | H | P | . |
. |
. |
. |
V | T | E | M | I | T | G | V | D | L | I | K | E | . |
. |
. |
Q | L | R | I | A | A |
Query Conservation |   |
  |   |   | . | . | . | . |   |   |   |   |   |   |
|
|
|
|   |   |   | . | . | . |   |   |   |   |
|   |
Alig confidence |   |
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
Template Conservation |   |
  |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|
|   |   |
|
|   |   |
|   |
Template Sequence |   |
T | S | Y | S | R | Y | P | R | M | M | A | A | A | G | I | S | L | P | E | L | I | D | R | L | I | V | L | A | L |
Template Known Secondary structure |   |
S | T | T |
|  |  |  |  |  |  |  |  | T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
Template Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
313 | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . |
  |