|   |
5 | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
I | R | Y | W | E | N | D | A | T | N | K | H | Y | A | I | A | H | F | N | V | W | N | A | E | M | L | M | G | V | I | D | A | A | E | E | A | K | S | P | V | I | I | S | F | G | T | G | F | V | G | N | T | S | F | E | D | F | S | H | M | M | V | S | M | A | Q | K | A | T | V | P | V | I | T | H | W | D | H | G | R |
Query Conservation |   |
  |
|   |
|
|   |   |
|   |   |   |   |
|
|
|   |
|
|
|
|   |
|   |
|   |   |   |
|
|
|   |
|
|
|   |   |   |
|
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |
|
|
|   |
|
|
|
|
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |
|   |   |   |   |
|
|   |
|
|   |   |   |   |   |
|   |   |   |   |   |
|   |
|   |   |   |
|
|
|   |   |
| . |
|
|
|   |   |   |   |   | . | . | . | . | . | . |   |   |   |   |
|   |   |
|   |   |   |   |   |   | . |   |   |
|
|
|
|   |
|   |
Template Sequence |   |
T | T | Q | Q | I | I | E | K | L | R | E | L | K | I | V | P | V | I | A | L | D | N | A | D | D | I | L | P | L | A | D | T | L | A | K | N | G | L | S | V | A | . |
E | I | T | F | R | S | E | A | . |
. |
. |
. |
. |
. |
A | A | D | A | I | R | L | L | R | A | N | R | P | D | . |
F | L | I | A | A | G | T | V | L |
Template Known Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |
|
| S | S | G | G | G |  |  |  |  |  |  |  |  |  |  | T | T |
|
|  |  | . |  |  |  | T | T | S | T | T | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |
| T | T | . |
|  |  |  |  |  | S |
|
|
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  | . |  |  |  |
|
|
|
|
| . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |
|
|
| . |
|  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
4 | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | |
. | . | . | . | . | 50 | . | . | |
|
|
|
|
|
. | . | . | . | . | . | . | 60 | . | . | . | . | . | . | |
. | . | . | 70 | . | . | . | . | . |
  |
  |   |
85 | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
S | M | E | I | I | H | N | A | W | T | H | G | M | N | S | L | M | R | D | A | S | A | F | D | F | E | E | N | I | R | L | T | K | E | A | V | D | F | F | H | P | L | G | I | P | V | E | A | E | L | G | H | V | G | N | E | T | V | Y | E | E | A | L | A | G | Y | H | Y | T | D | P | D | Q | A | A | E | F | V | E | R |
Query Conservation |   |
  |   |
|   |
|   |   |
|
|   |   |
|
|
|
|
|
|
|
|
|
|   |
|   |   |
|
|
|
|   |   |
|   |
|
|
|   |   |
|
|   |   |
|
|   |
|
|   |
|
|
|   |
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|
|   |   |
|
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
| . |
Template Conservation |   |
  |   |   |   |   |   |   |
|   |   |
|
|
|   |   |
|   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . |   |   |
|   |   |   |
|   |   |   |
|   |   |   |   |   |
|   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |
|   |   |
|   |   |   |
|   |   | . |
Template Sequence |   |
T | A | E | Q | V | V | L | A | K | S | S | G | A | D | F | V | V | T | P | G | L | N | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
P | K | I | V | K | L | C | Q | D | L | N | F | P | I | T | P | G | V | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
N | N | P | X | A | I | E | I | A | L | E | . |
Template Known Secondary structure |   |
S |  |  |  |  |  |  |  |  |  |  | T |
| S |  |  |  |
| S | S |
|
| . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |
|  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| S |  |  |  |  |  |  |  |  |  | . |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
76 | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
. | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | 120 | . | . | . | . | . | . | |
  |
  |   |
165 | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | |
200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . |
Predicted Secondary structure |   |
 |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  | . |
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | G | C | D | S | L | A | V | A | I | G | N | Q | H | G | V | Y | T | S | E | P | Q | L | N | F | E | V | V | K | R | V | R | D | A | V | . |
S | V | P | L | V | L | H | G | A | S | G | I | S | D | A | D | I | K | T | A | I | S | L | G | I | A | K | I | N | I | H | T | E | L | C | Q | A | A | M | V | A | V | K | E |
Query Conservation |   |
|
|
|
|   |
|
|
|
|
|
|
|   |
|
|   |
|   |   |   |
|   |
|
|   |   |   |
|   |   |
|   |   |   |
| . |   |
|
|
|
|
|
|
|
|
|
|   |   |   |   |   |   |   |   |
|
|   |   |
|
|   |
|
|
|
|   |
|   |
|   |   |
|   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |
|
|
|   |
| . | . | . | . | . | . | . | . |   |
|   |
|
|   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |   |   |   |
|
|   |
|
|   |
|
| . | . |
|   |   |   |
|   |   |   |   |
|   |
|
|
|   |   |
|   |
|
|
|   |
| . | . | . | . | . | . | . | . | . | . |
Template Sequence |   |
X | G | I | S | A | V | . |
. |
. |
. |
. |
. |
. |
. |
K | F | F | P | A | E | A | S | G | G | V | K | X | I | K | A | L | L | G | P | Y | A | Q | L | Q | I | X | P | T | G | G | . |
. |
I | G | L | H | N | I | R | D | Y | L | A | I | P | N | I | V | A | C | G | G | S | W | F | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
T | T |
|
|  |  | . | . | . | . | . | . | . | . |  |  | T | T | T | T | T | T | T |  |  |  |  |  |  |  |  |  | T | T | T | T | T |
|  |  |  |  | B | S | S | . | . |
|
| T | T | T |  |  |  |  |  | T | S | T | T | B |
|
|  |  |  |
| G | G | . | . | . | . | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
|
|
|
|  |  | . | . | . | . | . | . | . | . |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|  |  | . | . | . | . | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
127 | . | . | 130 | . | . | |
|
|
|
|
|
|
|
. | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | |
|
. | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
  |
  |   |
244 | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . |
Predicted Secondary structure |   |
 |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
N | Q | D | Q | P | F | L | H | L | E | R | E | V | R | K | A | V | K | E | R | A | L | E | K | I | K | L | F |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |
Alig confidence |   |
. | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . | . |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
. |
. |
. |
V | E | K | K | L | I | Q | S | N | N | W | D | E | I | G | R | L | V | R | E | V | I | D | I | I |
Template Known Secondary structure |   |
. | . | . | G |
|  |  |  |  |  | T | T |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
. | . | . |
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
187 | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . |
  |