Job Description P77704 Confidence 97.65% Date Thu Jan 5 12:31:54 GMT 2012 Rank 44 Aligned Residues 218 % Identity 18% Template c2cw6B_ PDB info PDB header:lyase Chain: B: PDB Molecule:hydroxymethylglutaryl-coa lyase, mitochondrial; PDBTitle: crystal structure of human hmg-coa lyase: insights into2 catalysis and the molecular basis for3 hydroxymethylglutaric aciduria Resolution 2.10 Å

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		25	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		W	N	A	E	M	L	M	G	V	I	D	A	A	E	E	A	K	S	P	V	I	I	S	F	G	T	G	F	V	G	N	T	S	F	E	D	F	S	H	M	M	V	S	M	A	Q	K	A	T	V	P	V	I	T	H	W	D	H	G	R	S	M	E	I	I	H	N	A	W	T	H	G	M	N	S	L	M	R	D	A
Query Conservation
Alig confidence																																																											.	.
Template Conservation																																																											.	.
Template Sequence		V	S	T	P	V	K	I	K	L	I	D	M	L	S	E	A	G	L	S	V	I	E	T	T	S	F	V	S	P	K	W	V	P	Q	M	G	D	H	T	E	V	L	K	G	I	Q	K	F	P	G	I	N	Y	P	V	L	T	.	.	P	N	L	K	G	F	E	A	A	V	A	A	G	A	K	E	V	V	I	F	G
Template Known Secondary structure																	T	T		S										T	T	T		G	G	G	T	T								S				T	T		B						.	.		S										T	T		S
Template Predicted Secondary structure																																																											.	.
Template SS confidence
		51	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.			.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.
		105	.	.	.	.											110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.				.	.	.	.	.			.
Predicted Secondary structure							.	.	.	.	.	.	.	.	.	.																																																							.	.	.						.	.
Query SS confidence							.	.	.	.	.	.	.	.	.	.																																																							.	.	.						.	.
Query Sequence		S	A	F	D	F	.	.	.	.	.	.	.	.	.	.	E	E	N	I	R	L	T	K	E	A	V	D	F	F	H	P	L	G	I	P	V	E	A	E	L	G	H	V	G	N	E	T	V	Y	E	E	A	L	A	G	Y	H	Y	T	D	P	D	Q	A	A	E	F	V	E	.	.	.	R	T	G	C	D	.	.	S
Query Conservation							.	.	.	.	.	.	.	.	.	.																																																							.	.	.						.	.
Alig confidence							.	.	.	.	.	.	.	.	.	.																																					.	.	.	.	.	.	.												.	.	.						.	.
Template Conservation																																																					.	.	.	.	.	.	.
Template Sequence		A	A	S	E	L	F	T	K	K	N	I	N	C	S	I	E	E	S	F	Q	R	F	D	A	I	L	K	A	A	Q	S	A	N	I	S	V	R	G	Y	V	S	C	A	L	G	C	P	Y	E	G	K	.	.	.	.	.	.	.	I	S	P	A	K	V	A	E	V	T	K	K	F	Y	S	M	G	C	Y	E	I	S
Template Known Secondary structure			S									T	S	S		T	T	T															T	T									S	T	T		B	T	T	T	B	S	.	.	.	.	.	.	.																T	T		S
Template Predicted Secondary structure																																																					.	.	.	.	.	.	.
Template SS confidence
		129	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.								180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.
		170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.		200	.	.	.	.	.	.	.	.	.			210	.	.	.	.	.	.	.	.	.	220	.	.	.	.																			.	.	.	.
Predicted Secondary structure																																.											.	.																.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence																																.											.	.																.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		L	A	V	A	I	G	N	Q	H	G	V	Y	T	S	E	P	Q	L	N	F	E	V	V	K	R	V	R	D	A	V	.	S	V	P	L	V	L	H	G	A	S	.	.	G	I	S	D	A	D	I	K	T	A	I	S	L	G	I	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	A	K	I	N
Query Conservation																																.											.	.																.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence								.	.	.	.	.	.																			.											.	.																.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation								.	.	.	.	.	.
Template Sequence		L	G	D	T	I	G	.	.	.	.	.	.	V	G	T	P	G	I	M	K	D	M	L	S	A	V	M	Q	E	V	P	L	A	A	L	A	V	H	C	H	D	T	Y	G	Q	A	L	A	N	T	L	M	A	L	Q	M	G	V	S	V	V	D	S	S	V	A	G	L	G	G	C	P	Y	A	Q	G	A	S	G	N
Template Known Secondary structure					T	T		.	.	.	.	.	.																		S		G	G	G						B		T	T	S												T	T							B	T	T	S					T	T	S	S	S				B
Template Predicted Secondary structure								.	.	.	.	.	.
Template SS confidence
		202	.	.	.	.	.							.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.
		229	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		I	H	T	E	L	C	Q	A	A	M	V	A	V	K	E	N	Q	D	Q	P	F	L	H	L	E	R	E	V	R
Query Conservation
Alig confidence
Template Conservation
Template Sequence		L	A	T	E	D	L	V	Y	M	L	E	G	L	G	I	H	T	G	V	N	L	Q	K	L	L	E	A	G	N
Template Known Secondary structure			B											T	T		B
Template Predicted Secondary structure
Template SS confidence
		276	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
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