|   |
83 | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | |
. | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | . |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | S | Y | V | T | L | A | E | K | I | N | A | L | A | P | V | S | G | Q | A | K | T | A | F | F | T | T | G | A | E | A | V | E | N | A | V | K | I | A | R | . |
A | H | T | G | R | P | G | V | I | A | F | S | G | G | F | H | G | R | T | Y | M | T | M | A | L | T | G | K | V | A | P | Y | K | I | G | F | G | P | F |
Query Conservation |   |
  |   |   |   |   |
|
|   |   |
|   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |
|
|
|   |
|   |   |   |
|
|   |
|
|   | . |   |   |   |   |
|   |   |
|
|   |   |   |   |   |   |
|
|   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |   |
|   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |
|   |   |   |   |
|   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |
|   |
|   |   |
|
|   |   |   |   |
| . | . | . | . | . | . | . | . | . | . | . | . |
Template Sequence |   |
K | I | T | N | S | L | V | L | D | I | I | K | L | A | G | V | H | T | V | A | N | C | F | V | V | P | M | A | T | G | M | S | L | T | L | C | F | L | T | L | R | H | K | R | P | K | A | K | Y | I | I | W | P | R | I | D | Q | K | S | C | F | K | S | M | I | T | A | G | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
| T | T |
|
|  |  |  |  |  | S | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| T | T |
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  | T | T | . | . | . | . | . | . | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
| . | . | . | . | . | . | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
116 | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
  |
  |   |
162 | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . |
Predicted Secondary structure |   |
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
P | G | S | V | Y | H | V | P | Y | P | S | D | L | H | G | I | S | T | Q | D | S | L | D | A | I | E | R | L | F | K | S | D | I | E | A | K | Q | V | A | A | I | I | F | E | P | V | Q | G | E | G | G | F | N | V | A | P | K | E | L | V | A | A | I | R | R | L | C | D | E | H | G | I | V | M | I | A | D | E | V | Q |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |
|   |
|
|   |
|
|
|   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |
|   |   |
|   |   |   |   |
|   |   |
|
|   |
|
|   |   |
Alig confidence |   |
. | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . | . |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |   |   | . |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |
|   | . | . | . | . |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |
Template Sequence |   |
. |
. |
. |
F | E | P | V | V | I | E | N | V | L | E | G | D | E | L | R | T | D | L | K | A | V | E | A | K | V | Q | E | L | G | . |
P | D | C | I | L | C | I | H | S | T | T | S | C | F | A | P | R | V | P | D | R | . |
. |
. |
. |
L | E | E | L | A | V | I | C | A | N | Y | D | I | P | H | I | V | N | N | A | Y |
Template Known Secondary structure |   |
. | . | . |
|  |  |  |  |  |
|
|  |  |  | T | T |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |
| . | G | G | G |  |  |  |  |  |  |  | S | S |
|
| T | T | B |
|
|
|
| . | . | . | . |  |  |  |  |  |  |  |  |  |  |  | T |
|
|  |  |  |  |
| T | T |
Template Predicted Secondary structure |   |
. | . | . |
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
| . |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
184 | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | |
. | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | |
|
|
|
. | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . |
  |
  |   |
242 | . | . | . | . | . | |
|
|
. | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | |
. | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
| . | . | . |
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  | . |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
S | G | F | A | R | T | . |
. |
. |
G | K | L | F | A | M | D | H | Y | A | D | K | P | D | L | M | T | M | A | K | S | L | A | G | G | M | P | L | S | G | V | V | G | N | . |
A | N | I | M | D | A | P | A | P | G | G | L | G | G | T | Y | A | G | N | P | L | A | V | A | A | A | H | A | V | L | N | I | I | D | K | E |
Query Conservation |   |
|
|   |
|   |   | . | . | . |
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |
|
|   |
|   |   |   |   |   |   |
|   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |
|
|   |   |   |   |
|   |
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |
Template Sequence |   |
G | V | Q | S | S | K | C | M | H | L | I | Q | Q | G | A | R | V | G | R | I | D | A | F | V | Q | S | L | D | K | N | F | M | V | P | V | G | G | A | I | I | A | G | F | N | D | S | F | I | Q | E | I | S | K | M | Y | P | G | R | A | S | A | S | P | S | L | D | V | L | I | T | L | L | S | L | G | S | N | G | Y | K |
Template Known Secondary structure |   |
| T | T |
|  |  |  |  |  |  |  |  |  |  |  |  |  | S |
|
|
|  |  |  |  |  |  |  |  |  | S |
|
|
| S | S |
|  |  |  |  |  | S |
|  |  |  |  |  |  |  |  |  | T | S |
| S |
| B |
| S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
256 | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . |
  |
  |   |
318 | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | |
. | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | |
|
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . |
|
|  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |
|
|
|
|
|  | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
Query Sequence |   |
S | L | C | E | R | A | N | Q | L | G | Q | R | L | K | N | T | L | I | D | A | K | E | S | V | P | . |
A | I | A | A | V | R | G | L | G | S | M | I | A | V | E | F | N | D | P | Q | T | G | E | P | S | A | A | I | A | Q | K | I | Q | Q | R | A | L | A | Q | G | L | L | L | L | T | C | G | A | Y | G | N | V | . |
. |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   | . |   |
|   |   |
|   |
|   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |
|
|   |
|   |   |   |   |   |   |   |   |   | . | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . |   |   |   |
|   |   |   |
|   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
K | L | L | K | E | R | K | E | M | F | S | Y | L | S | N | Q | I | K | K | L | S | E | A | Y | N | E | R | L | L | H | T | P | H | N | P | I | S | L | A | M | T | L | K | T | L | D | E | H | R | D | K | A | . |
. |
V | T | Q | L | G | S | M | L | F | T | R | Q | V | S | G | A | R | V | V | P | L | G | S | M | Q | T |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
| B |
|
|
| T | T |
| S | S |  |  |  |  |  |
| T | T |
|
| T | T | T | S |
|
| . | . |  |  |  |  |  |  |  |  |  |  | T | T |
|
| S |
|  |  |  |
| S | S |
|  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
| . | . |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
336 | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | |
|
. | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . |
  |
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
395 | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . |
Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
I | R | F | L | Y | P | L | T | I | P | D | A | Q | F | D | A | A | M | K | I | L | Q | D | A | L | S | D |
Query Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|   |   |   |
|   |   |   |
|   |   |   |
|   |   |   |
|   |   |
|   |   |
|
|   |
|
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |
|   |   |   |
|
|
|
|
|
|   |
|
|   |   |
|   |
|
|
|
|
|
Template Sequence |   |
V | S | G | Y | T | F | R | G | F | M | S | H | T | N | N | Y | P | C | A | Y | L | N | A | A | S | A | I | G | M | K | M | Q | D | V | D | L | F | I | K | R | L | D | R | C | L | K | A |
Template Known Secondary structure |   |
 | T | T |  |  |  |  | S | T | T | T | T | S | S |
|
| S | S |
|  |  |  |  |  |
|
| T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
414 | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 |
  |