Job Description Q5H772 Confidence 99.93% Date Thu Jan 5 12:37:18 GMT 2012 Rank 130 Aligned Residues 350 % Identity 16% Template c3e9kA_ PDB info PDB header:hydrolase Chain: A: PDB Molecule:kynureninase; PDBTitle: crystal structure of homo sapiens kynureninase-3-hydroxyhippuric acid2 inhibitor complex Resolution 1.70 Å

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		37	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.							80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110
Predicted Secondary structure																																													.	.	.	.	.	.
Query SS confidence																																													.	.	.	.	.	.
Query Sequence		V	E	G	N	E	Y	I	D	F	A	A	G	I	A	V	L	N	T	G	H	R	H	P	D	L	V	A	A	V	E	Q	Q	L	Q	Q	F	T	H	T	A	Y	Q	I	.	.	.	.	.	.	V	P	Y	E	S	Y	V	T	L	A	E	K	I	N	A	L	A	P	V	S	G	Q	A	K	T	A	F	F	T	T	G
Query Conservation																																													.	.	.	.	.	.
Alig confidence														.	.	.	.																												.	.	.	.	.	.																				.
Template Conservation														.	.	.	.																																																					.
Template Sequence		N	K	D	E	N	A	I	Y	F	L	G	N	.	.	.	.	S	L	G	L	Q	P	K	M	V	K	T	Y	L	E	E	E	L	D	K	W	A	K	I	A	A	Y	G	H	E	V	G	K	R	P	W	I	T	G	D	E	S	I	V	G	L	M	K	D	I	V	G	A	.	N	E	K	E	I	A	L	M	N	A	L
Template Known Secondary structure			T	T		B					B	T	T	.	.	.	.	T	S			B		T	T																G	G	G	G	G	T	S	S	S	S		G	G	G	T	T					G	G	G					T		.		G	G	G					S
Template Predicted Secondary structure														.	.	.	.																																																					.
Template SS confidence
		63	.	.	.	.	.	.	70	.	.	.	.					.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.		.	.	.	130	.	.	.	.	.	.	.
		111	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190
Predicted Secondary structure
Query SS confidence
Query Sequence		A	E	A	V	E	N	A	V	K	I	A	R	A	H	T	G	R	P	G	V	I	A	F	S	G	G	F	H	G	R	T	Y	M	T	M	A	L	T	G	K	V	A	P	Y	K	I	G	F	G	P	F	P	G	S	V	Y	H	V	P	Y	P	S	D	L	H	G	I	S	T	Q	D	S	L	D	A	I	E	R	L	F
Query Conservation
Alig confidence																																							.	.	.	.	.	.																									.	.	.
Template Conservation																																							.	.	.	.	.	.																									.	.	.
Template Sequence		T	V	N	L	H	L	L	M	L	S	F	F	K	P	T	P	K	R	Y	K	I	L	L	E	A	K	A	F	P	S	D	H	Y	A	I	E	S	.	.	.	.	.	.	Q	L	Q	L	H	G	L	N	I	E	E	S	M	R	M	I	K	P	R	E	G	E	E	T	.	.	.	L	R	I	E	D	I	L	E	V	I
Template Known Secondary structure																	S	S	S							T	T												.	.	.	.	.	.					T	T														T	T		S	S	.	.	.
Template Predicted Secondary structure																																							.	.	.	.	.	.																									.	.	.
Template SS confidence
		138	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.							.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.				.	200	.	.	.	.	.	.	.	.
		191	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270
Predicted Secondary structure
Query SS confidence
Query Sequence		K	S	D	I	E	A	K	Q	V	A	A	I	I	F	E	P	V	Q	G	E	G	G	F	N	V	A	P	K	E	L	V	A	A	I	R	R	L	C	D	E	H	G	I	V	M	I	A	D	E	V	Q	S	G	F	A	R	T	G	K	L	F	A	M	D	H	Y	A	D	K	P	D	L	M	T	M	A	K	S	L	A
Query Conservation
Alig confidence					.	.																						.	.	.	.																												.	.	.
Template Conservation					.	.																						.	.	.	.																												.	.	.
Template Sequence		E	K	E	.	.	G	D	S	I	A	V	I	L	F	S	G	V	H	F	Y	T	G	Q	H	F	N	.	.	.	.	I	P	A	I	T	K	A	G	Q	A	K	G	C	Y	V	G	F	D	L	A	H	A	V	G	N	V	E	.	.	.	L	Y	L	H	D	W	G	V	D	F	A	C	W	C	S	Y	K	Y	L	N
Template Known Secondary structure					.	.	G	G	G								S	B		T	T	T		B	B			.	.	.	.											T	T								T	T	T	T	T	T	S		.	.	.							T								S	S	S	T	T
Template Predicted Secondary structure					.	.																						.	.	.	.																												.	.	.
Template SS confidence
		209	210	.			.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.					.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.				260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.
		271	.		.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.																										.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.				.	.	.	320	.
Predicted Secondary structure				.																								.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																						.	.	.
Query SS confidence				.																								.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																						.	.	.
Query Sequence		G	G	.	M	P	L	S	G	V	V	G	N	A	N	I	M	D	A	P	A	P	G	G	L	G	G	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	T	Y	A	G	N	P	L	A	V	A	A	A	H	A	V	L	N	I	I	D	K	.	.	.	E	S	L	C	E
Query Conservation				.																								.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																						.	.	.
Alig confidence				.																								.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																						.	.	.
Template Conservation
Template Sequence		A	G	A	G	G	I	A	G	A	F	I	H	E	K	H	A	H	T	I	K	P	A	L	V	G	W	F	G	H	E	L	S	T	R	F	K	M	D	N	K	L	Q	L	I	P	G	V	C	G	F	R	I	S	N	P	P	I	L	L	V	C	S	L	H	A	S	L	E	I	F	K	Q	A	T	M	K	A	L	R	K
Template Known Secondary structure				T	T									G	G	G	T	T	T	S			S	S			G	G	G	B						T	T			S				B		S	S	G	G	G	G			S
Template Predicted Secondary structure
Template SS confidence
		280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.
		322	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.			.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.
Predicted Secondary structure																										.	.
Query SS confidence																										.	.
Query Sequence		R	A	N	Q	L	G	Q	R	L	K	N	T	L	I	D	A	K	E	S	V	P	A	I	A	.	.	A	V	R	G	L	G	S	M	I	A	V	E	F	N	D	P	Q	T	G	E	P	S	A	A	I	A	Q	K	I	Q	Q	R	A	L	A	Q	G	L	L	L	L	T	C	G	A	Y	G	N	V	I	R	F	L	Y
Query Conservation																										.	.
Alig confidence																										.	.																			.	.	.	.	.	.	.	.	.																				.	.
Template Conservation																																														.	.	.	.	.	.	.	.	.																				.	.
Template Sequence		K	S	V	L	L	T	G	Y	L	E	Y	L	I	K	H	N	Y	G	V	V	N	I	I	T	P	S	H	V	E	E	R	G	C	Q	L	T	I	T	F	S	V	P	N	K	.	.	.	.	.	.	.	.	.	D	V	F	Q	E	L	E	K	R	G	V	V	C	D	K	R	N	P	N	.	.	G	I	R	V	A	P
Template Known Secondary structure																									S		S	S	G	G	G	B		S									T	T		.	.	.	.	.	.	.	.	.								T	T	T							T	T	T	.	.					B
Template Predicted Secondary structure																																														.	.	.	.	.	.	.	.	.																				.	.
Template SS confidence
		360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.										.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.			.	.	.	.	.	.
			400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Predicted Secondary structure		.
Query SS confidence		.
Query Sequence		.	P	L	T	I	P	D	A	Q	F	D	A	A	M	K	I	L	Q	D	A	L	S
Query Conservation		.
Alig confidence		.
Template Conservation
Template Sequence		V	P	L	Y	N	S	F	H	D	V	Y	K	F	T	N	L	L	T	S	I	L	D
Template Known Secondary structure			T	T	T																		T
Template Predicted Secondary structure
Template SS confidence
		438	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.

No model constructed - rank, confidence too low

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Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions