|   |
468 | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | |
. | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |
|
| . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
S | D | L | E | T | A | I | V | V | V | D | R | F | S | G | E | V | R | A | M | V | G | G | S | E | P | Q | F | A | G | Y | N | R | A | M | Q | A | R | . |
R | S | I | G | S | L | A | K | P | A | T | Y | L | T | A | L | S | Q | P | K | I | Y | R | L | N | T | W | I | A | D | A | P | I | A | L | R | Q | P | N | G | Q |
Query Conservation |   |
  |   |
|
|
|
|   |
|
|
|
|
|   |
|
|
|
|
|
|
|
|
|
|   |
|   |   |   |   |   |   |
|
|
|   |   |
|   | . |
|
|
|
|
|
|
|
|
|   |
|
|
|
|
|
|
|   |
|   |   |   |
|   |   |
|   |
|   |
|   |
|   |   |   |   |   |   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
Template Conservation |   |
  |   |   |   |
|   |
|
|   |   |
|   |   |
|
|   |   |   |   | . | . | . | . | . | . | . | . | . | . | . |   |
|   |   |
|
|   |   |   |   |   |
|
|
|
|
|
|   |   |
|   |   |
|
|
|
|   |
|   |   | . |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . |   |   |   |
Template Sequence |   |
G | S | N | S | G | S | F | V | M | Y | S | M | K | K | D | K | Y | Y | I | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Y | N | E | K | E | S | R | K | R | Y | S | P | N | S | T | Y | K | I | Y | L | A | M | F | G | L | D | R | H | I | I | . |
N | D | E | N | S | R | M | S | W | . |
. |
. |
. |
. |
. |
. |
N | H | K |
Template Known Secondary structure |   |
T | T |
|  |  |  |  |  |  |  |  | T | T | T | T |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . |  | S |  |  |  |  | T |
|  |  |
|
| G | G | G | G |  |  |  |  |  |  |  |  |  |  | T | T | S | S | . |
| S | S |
|
|
| B |
|
| . | . | . | . | . | . | . |
| S |
|
Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  | . | . | . | . | . | . | . | . | . | . | . |  |
|  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
| . |
|
|
|
|  |  |  |  |
| . | . | . | . | . | . | . |
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
27 | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
. | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | |
. | . | . | . | 80 | . | . | . | . | |
|
|
|
|
|
|
. | . | . |
  |
  |   |
547 | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . | |
. | . | . | 610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
| . |
|
|  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | W | S | P | Q | N | D | D | R | R | Y | S | E | S | G | R | V | M | L | V | D | A | L | T | R | S | M | N | V | P | T | V | N | L | G | M | A | L | G | L | P | A | V | T | E | T | W | I | K | L | G | V | P | K | D | Q | L | H | P | V | . |
P | A | M | L | L | G | A | L | N | L | T | P | I | E | V | A | Q | A | F |
Query Conservation |   |
  |
|   |
|   |
|
|
|   |   |   |   |   |   |
|   |
|
|
|   |   |
|
|
|   |
|   |
|
|   |   |
|   |
|   |   |   |
|
|   |
|   |
|   |   |   |   |   |   |
|
|
|   |   |   |   |   |   |   |   | . |
|
|
|
|
|
|   |   |   |
|
|
|
|
|
|
|   |
|
|
Alig confidence |   |
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   | . | . | . | . | . | . |   |   |   |   |
|
|   |   |
|
|   |   |
|   |
|   |   |   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|
|   |
|   |
|   |   |   |
Template Sequence |   |
H | Y | P | F | D | A | W | . |
. |
. |
. |
. |
. |
N | K | E | Q | D | L | N | T | A | M | Q | N | S | V | N | W | Y | F | E | R | I | S | D | Q | I | P | K | N | Y | T | A | T | Q | L | K | Q | L | N | Y | G | N | K | N | L | G | S | Y | K | S | Y | W | M | E | D | S | L | K | I | S | N | L | E | Q | V | I | V | F |
Template Known Secondary structure |   |
|
| S | S | G | G | G | . | . | . | . | . | . | S | S |
| B |
|  |  |  |  |  |  |  | T |
|  |  |  |  |  |  |  |  |  | T | S |
|  |  |  |  |  |  |  |  |  |  |  | T |
| T | T |
|
|
| T | T | S | S | S | T | T | S | S | S | S |
|
|  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
|  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
88 | . | 90 | . | . | . | . | |
|
|
|
|
|
. | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . |
  |
  |   |
626 | . | . | . | 630 | . | . | . | . | . | . | . | . | . | 640 | . | . | . | . | . | . | . | . | . | 650 | . | . | . | . | . | . | . | . | . | 660 | . | . | . | . | . | . | . | . | . | 670 | . | . | . | . | . | . | . | . | . | 680 | . | . | . | . | . | . | . | . | . | 690 | . | . | . | . | . | . | . | . | . | 700 | . | . | |
|
|
Predicted Secondary structure |   |
 |  |  |  |
|
|
|  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
| . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
Query Sequence |   |
Q | T | I | A | S | G | G | N | R | A | P | L | S | A | L | R | S | V | I | A | E | D | G | K | V | L | Y | Q | S | F | P | Q | A | E | R | A | V | P | A | Q | A | A | Y | L | T | L | W | T | M | Q | Q | V | V | Q | R | G | T | G | R | Q | L | G | A | K | Y | P | N | L | H | L | A | G | K | T | G | T | T | . |
. |
. |
Query Conservation |   |
|
|
|
|
|
|
|   |   |   |   |
|   |   |
|   |   |
|   |
|   |   |
|   |
|
|   |   |   |   |   |   |   |   |   |
|
|
|   |   |   |
|   |   |
|   |   |   |
|   |   |
|
|   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|
|
| . | . | . |
Alig confidence |   |
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
| . | . | . |
Template Conservation |   |
  |   |
|
|
|   |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |
| . | . | . | . | . | . | . | . | . | . | . |   |   |
|   |
|
|
|
|
|
|   |   |   |
Template Sequence |   |
K | N | M | M | E | N | H | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
F | S | K | K | A | K | N | Q | L | S | S | S | L | L | I | K | K | N | E | K | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Y | E | L | Y | G | K | T | G | T | G | I | V | N |
Template Known Secondary structure |   |
 |  |  |  |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| S | S | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  | T |
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|  |  |  |
|
|  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
162 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
. | 190 | . | . | . | . | . | . | . | . | . | 200 | . |
  |
  |   |
703 | . | . | . | . | . | . | 710 | . | . | . | |
|
|
|
. | . | . | . | . | . | 720 | . | . | . | . | . | . | . | . | . | 730 | . | . | . | . | . | . | . | . | . | 740 | . | . | . | . | . | . | . | . | . | 750 |
Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  | . | . | . | . |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
N | N | N | V | D | T | W | F | A | G | I | . |
. |
. |
. |
D | G | S | T | V | T | I | T | W | V | G | R | D | N | N | Q | P | T | K | L | Y | G | A | S | G | A | M | S | I | Y | Q | R | Y | L | A | N | Q |
Query Conservation |   |
  |
|   |
|
|
|
|
|
|
|
| . | . | . | . |
|
|   |   |
|   |   |
|
|
|
|   |
|
|   |   |   |   |   |   |
|
|   |   |   |
|
|
|
|
|   |   |   |
|   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |
|
|
|
|   |   |
|   |   |   |   |   |   |   |   |
|
|   |
| . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |
|
|   |   |
|
Template Sequence |   |
G | K | Y | N | N | G | W | F | V | G | Y | V | I | T | N | H | D | K | Y | Y | F | A | T | H | L | . |
. |
. |
. |
. |
. |
S | D | G | K | P | S | G | K | N | A | E | L | I | S | E | K | I | L | K | E | M |
Template Known Secondary structure |   |
T |  |  |  |  |  |  |  |  |  |  |  |  |  | S | S |
|  |  |  |  |  |  |  |  | . | . | . | . | . | . |  |  | S | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
Template Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  | . | . | . | . | . | . |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
204 | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
. | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . |
  |