|   |
459 | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | |
. | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |
|
|
| . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
P | A | L | K | K | Q | R | K | L | S | D | L | E | T | A | I | V | V | V | D | R | F | S | G | E | V | R | A | M | V | G | G | S | E | P | Q | F | A | G | Y | N | R | A | M | Q | A | R | R | . |
S | I | G | S | L | A | K | P | A | T | Y | L | T | A | L | S | Q | P | K | I | Y | R | L | N | T | W | I | A | D | A | P |
Query Conservation |   |
  |   |
|   |   |   |   |   |   |   |   |
|
|
|
|   |
|
|
|
|
|   |
|
|
|
|
|
|
|
|
|
|   |
|   |   |   |   |   |   |
|
|
|   |   |
|   |
| . |
|
|
|
|
|
|
|
|   |
|
|
|
|
|
|
|   |
|   |   |   |
|   |   |
|   |
|   |
|   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|   |
|   |   |
|
|   |
|   |   | . | . | . | . | . | . | . | . | . | . | . |   |
|   |   |   |
|   |   |   |   |   |
|
|
|
|
|
|   | . |   |   |   |
|
|
|
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
T | S | W | N | K | E | F | S | A | E | A | V | N | G | V | F | V | L | C | K | S | S | S | K | S | C | A | T | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
N | D | L | A | R | A | S | K | E | Y | L | P | A | S | T | F | I | P | . |
N | A | I | I | G | L | E | T | G | V | I | K | N | E | H | Q | V | F | K | W | D | G |
Template Known Secondary structure |   |
G | G | G | G |  |  |  |  | T | T | T |
|
|  |  |  |  |  |  |  | S | S | T | T | S |  |  |  | . | . | . | . | . | . | . | . | . | . | . | S |
|  |  |  |  | T |
|
| B |
|
| G | G | G |
|
|  | . |  |  |  |  |  |  |  | T | T | S | S |
| S | T | T |
|  |  |
|
|
| S |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  | . | . | . | . | . | . | . | . | . | . | . |  |
|  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  | . |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
26 | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | |
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | |
. | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . |
  |
  |   |
538 | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . | . | . | . | 610 | . | |
|
. | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  | . | . |
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
Query Sequence |   |
I | A | L | R | Q | P | N | G | Q | V | W | S | P | Q | N | D | D | R | R | Y | S | E | S | G | R | V | M | L | V | D | A | L | T | R | S | M | N | V | P | T | V | N | L | G | M | A | L | G | L | P | A | V | T | E | T | W | I | K | L | G | V | P | K | D | Q | L | H | P | V | P | A | M | L | L | . |
. |
G | A | L | N |
Query Conservation |   |
  |   |   |   |   |   |   |
|   |   |
|   |
|   |
|
|
|   |   |   |   |   |   |
|   |
|
|
|   |   |
|
|
|   |
|   |
|
|   |   |
|   |
|   |   |   |
|
|   |
|   |
|   |   |   |   |   |   |
|
|
|   |   |   |   |   |   |   |   |
|
|
|
|
| . | . |
|   |   |   |
Alig confidence |   |
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
Template Conservation |   |
  |   | . | . | . | . | . | . | . | . |   |   |   |   |   |   | . | . | . | . | . | . |   |
|   |   |
|
|   |   |
|
|   |   |
|   |
|   |   |   |   |   |
|   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |
Template Sequence |   |
K | P | . |
. |
. |
. |
. |
. |
. |
. |
R | A | M | K | Q | W | . |
. |
. |
. |
. |
. |
E | R | D | L | T | L | R | G | A | I | Q | V | S | A | V | P | V | F | Q | Q | I | A | R | E | V | G | E | V | R | M | Q | K | Y | L | K | K | F | S | Y | G | N | Q | N | I | S | G | G | I | D | K | F | W | L | E | G | Q | L | R |
Template Known Secondary structure |   |
|
| . | . | . | . | . | . | . | . |
| S | S | G | G | G | . | . | . | . | . | . | S | S |
|  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  | T | T |
| T | T |
|
|
|
| S |
| T | T | T | T | T | T | T | S | S |
|
|
Template Predicted Secondary structure |   |
 |  | . | . | . | . | . | . | . | . |  |  |  |
|
|
| . | . | . | . | . | . |
|
|
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
95 | . | |
|
|
|
|
|
|
|
. | . | . | 100 | . | . | |
|
|
|
|
|
. | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 |
  |
  |   |
616 | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | . | . | . | . | . | . | . | 640 | . | . | . | . | . | . | . | . | . | 650 | . | . | . | . | . | . | . | . | . | 660 | . | . | . | . | . | . | . | . | . | 670 | . | . | . | . | . | . | . | . | . | 680 | . | . | . | . | . | . | . | . | . | 690 | . | . | . | . | . |
Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | T | P | I | E | V | A | Q | A | F | Q | T | I | A | S | G | G | N | R | A | P | L | S | A | L | R | S | V | I | A | E | D | G | K | V | L | Y | Q | S | F | P | Q | A | E | R | A | V | P | A | Q | A | A | Y | L | T | L | W | T | M | Q | Q | V | V | Q | R | G | T | G | R | Q | L | G | A | K | Y | P | N | L | H | L |
Query Conservation |   |
|
|
|
|
|
|
|   |
|
|
|
|
|
|
|
|
|   |   |   |   |
|   |   |
|   |   |
|   |
|   |   |
|   |
|
|   |   |   |   |   |   |   |   |   |
|
|
|   |   |   |
|   |   |
|   |   |   |
|   |   |
|
|   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
Template Conservation |   |
|
|
|
|
|   |
|   |   |   |   |   |
|
|
|   |
|   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |
|   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . |   |   |
|
Template Sequence |   |
I | S | A | V | N | Q | V | E | F | L | E | S | L | Y | L | N | K | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
S | A | S | K | E | N | Q | L | I | V | K | E | A | L | V | T | E | A | A | P | E | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Y | L | V |
Template Known Secondary structure |   |
B |
|  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| S | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | S | S |
|  |  |  |  |  |  |  |  |  |  | T |  |  |  |  |  | T | T | . | . | . | . | . | . | . | . | . | . | . |  |  |  |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  | . | . | . | . | . | . | . | . | . | . | . |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
161 | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
200 | . | . |
  |
  |   |
696 | . | . | . | 700 | . | . | |
|
|
|
|
. | . | . | . | . | . | . | 710 | . | . | . | |
|
|
|
. | . | . | . | . | . | 720 | . | . | . | . | . | . | . | . | . | 730 | . | . | . | . | . | . | . | . | . | 740 | . | . | . | . | . | . | . | . | . | 750 | . |
Predicted Secondary structure |   |
 |  |  |  |
|
|
| . | . | . | . | . |
|
|
|
|
|  |  |  |  |  |  | . | . | . | . |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | G | K | T | G | T | T | . |
. |
. |
. |
. |
N | N | N | V | D | T | W | F | A | G | I | . |
. |
. |
. |
D | G | S | T | V | T | I | T | W | V | G | R | D | N | N | Q | P | T | K | L | Y | G | A | S | G | A | M | S | I | Y | Q | R | Y | L | A | N | Q | T |
Query Conservation |   |
|
|
|
|
|
|
| . | . | . | . | . |   |
|   |
|
|
|
|
|
|
|
| . | . | . | . |
|
|   |   |
|   |   |
|
|
|
|   |
|
|   |   |   |   |   |   |
|
|   |   |   |
|
|
|
|
|   |   |   |
|   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|
|
|
|
|
|   |   |
|   |   |   |   |   |   |   |   |
|
|
|
|   |   |
|   |   |   |   |   |
|   |   |   |
|   |
| . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |
|   |   |   |
|   |
Template Sequence |   |
H | S | K | T | G | F | S | G | V | G | T | E | S | N | P | G | V | A | W | W | V | G | W | V | E | K | E | T | E | V | Y | F | F | A | F | N | M | . |
. |
. |
. |
. |
D | I | D | N | E | S | K | L | P | L | R | K | S | I | P | T | K | I | M | E | S | E | G |
Template Known Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|
| S | S | S |
|  |  |  |  |  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  |  | . | . | . | . | . |  |  | S |
| G | G | G | T | T |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  | . | . | . | . | . |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
203 | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . |
  |