|   |
468 | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
S | D | L | E | T | A | I | V | V | V | D | R | F | S | G | E | V | R | A | M | V | G | G | S | E | P | Q | F | A | G | Y | N | R | A | M | Q | A | R | R | S | I | G | S | L | A | K | P | A | T | Y | L | T | A | L | S | Q | P | K | I | Y | R | L | N | T | W | I | A | D | A | P | I | A | L | R | Q | P | N | G | Q | V |
Query Conservation |   |
  |   |
|
|
|
|   |
|
|
|
|
|   |
|
|
|
|
|
|
|
|
|
|   |
|   |   |   |   |   |   |
|
|
|   |   |
|   |
|
|
|
|
|
|
|
|
|   |
|
|
|
|
|
|
|   |
|   |   |   |
|   |   |
|   |
|   |
|   |
|   |   |   |   |   |   |   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
Template Conservation |   |
  |   |   |   |
|   |   |
|   |   |
|   |   |
|
|   |
|   |   | . | . | . | . | . | . | . | . | . | . | . |   |
|   |   |   |   |   |   |   |   |
|
|
|
|
|
|   |   |
|   |   |
|
|
|
|   |
|   |
|   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . |   |   |   |   |
Template Sequence |   |
K | G | F | D | G | S | F | V | L | Y | N | E | R | E | Q | A | Y | S | I | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Y | N | E | P | E | S | K | Q | R | Y | S | P | N | T | Y | K | I | Y | L | A | L | M | A | F | D | Q | N | L | L | S | L | N | H | T | E | Q | Q | W | . |
. |
. |
. |
. |
. |
. |
. |
D | K | H | Q |
Template Known Secondary structure |   |
T | T | S |  |  |  |  |  |  |  |  | T | T | T | T |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . |  | S |  |  |  |  |  | B |  |  |
|
|
|
| T |  |  |  |  |  |  |  |  |  |  | T | T | S | S | B | T | T | B |
|
| B |
|
| . | . | . | . | . | . | . | . |
|
|
|
|
Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  | . | . | . | . | . | . | . | . | . | . | . |  |
|  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |
|
| . | . | . | . | . | . | . | . |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
359 | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
. | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | |
|
|
|
|
|
|
|
. | . | . | . |
  |
  |   |
548 | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | |
. | . | . | . | . | 610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
| . |
|
|
|
|  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
W | S | P | Q | N | D | D | R | R | Y | S | E | S | G | R | V | M | L | V | D | A | L | T | R | S | M | N | V | P | T | V | N | L | G | M | A | L | G | L | P | A | V | T | E | T | W | I | K | L | G | V | P | K | D | Q | L | H | . |
P | V | P | A | M | L | L | G | A | L | N | L | T | P | I | E | V | A | Q | A | F | Q |
Query Conservation |   |
|   |
|   |
|
|
|   |   |   |   |   |   |
|   |
|
|
|   |   |
|
|
|   |
|   |
|
|   |   |
|   |
|   |   |   |
|
|   |
|   |
|   |   |   |   |   |   |
|
|
|   |   |   |   |   |   | . |   |   |
|
|
|
|
|
|   |   |   |
|
|
|
|
|
|
|   |
|
|
|
Alig confidence |   |
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   | . | . | . | . | . | . |   |   |   |   |
|
|   |   |
|
|   |   |
|   |
|   |   |   |   |   |
|   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|
|
|
|   |
|   |   |   |   |
Template Sequence |   |
Y | P | F | K | E | W | . |
. |
. |
. |
. |
. |
N | Q | D | Q | N | L | N | S | S | M | K | Y | S | V | N | W | Y | Y | E | N | L | N | K | H | L | R | Q | D | E | V | K | S | Y | L | D | L | I | E | Y | G | N | E | E | I | S | G | N | E | N | Y | W | N | E | S | S | L | K | I | S | A | I | E | Q | V | N | L | L | K |
Template Known Secondary structure |   |
| S | S | G | G | G | . | . | . | . | . | . | S | S |
| B |
|  |  |  |  |  |  | T | T |
|  |  |  |  |  |  |  |  |  |  | S |
|  |  |  |  |  |  |  |  |  |  |  | T |
| T | T |
|
|
|
| S |
| T | T | T | T | S | S | S | S |
|
|  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
421 | . | . | . | . | . | |
|
|
|
|
|
. | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . |
  |
  |   |
627 | . | . | 630 | . | . | . | . | . | . | . | . | . | 640 | . | . | . | . | . | . | . | . | . | 650 | . | . | . | . | . | . | . | . | . | 660 | . | . | . | . | . | . | . | . | . | 670 | . | . | . | . | . | . | . | . | . | 680 | . | . | . | . | . | . | . | . | . | 690 | . | . | . | . | . | . | . | . | . | 700 | . | . | . | |
|
|
Predicted Secondary structure |   |
 |  |  |
|
|
|  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
| . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
Query Sequence |   |
T | I | A | S | G | G | N | R | A | P | L | S | A | L | R | S | V | I | A | E | D | G | K | V | L | Y | Q | S | F | P | Q | A | E | R | A | V | P | A | Q | A | A | Y | L | T | L | W | T | M | Q | Q | V | V | Q | R | G | T | G | R | Q | L | G | A | K | Y | P | N | L | H | L | A | G | K | T | G | T | T | N | . |
. |
. |
Query Conservation |   |
|
|
|
|
|
|   |   |   |   |
|   |   |
|   |   |
|   |
|   |   |
|   |
|
|   |   |   |   |   |   |   |   |   |
|
|
|   |   |   |
|   |   |
|   |   |   |
|   |   |
|
|   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|
|
|   | . | . | . |
Alig confidence |   |
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
| . | . | . |
Template Conservation |   |
  |
|
|
|   |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |
|
|   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |
| . | . | . | . | . | . | . | . | . | . | . |   |   |
|
|
|
|
|
|
|   |   |   |   |   |
Template Sequence |   |
N | M | K | Q | H | N | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
M | H | F | D | N | K | A | I | E | K | V | E | N | S | M | T | L | K | Q | K | D | T | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Y | K | Y | V | G | K | T | G | T | G | I | V | N | H |
Template Known Secondary structure |   |
 |  |  | T | T |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | S | S | S |
|  |  |  |  |  |  |  |  |  |  | T |  |  |  |  |
| S | S | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
Template Predicted Secondary structure |   |
 |  |  |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|  |  |
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
495 | . | . | . | . | 500 | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | |
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | 530 | . | . | . | . | . | . |
  |
  |   |
704 | . | . | . | . | . | 710 | . | . | . | |
|
|
|
. | . | . | . | . | . | 720 | . | . | . | . | . | . | . | . | . | 730 | . | . | . | . | . | . | . | . | . | 740 | . | . | . | . | . | . | . | . | . | 750 | . |
Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  | . | . | . | . |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
N | N | V | D | T | W | F | A | G | I | . |
. |
. |
. |
D | G | S | T | V | T | I | T | W | V | G | R | D | N | N | Q | P | T | K | L | Y | G | A | S | G | A | M | S | I | Y | Q | R | Y | L | A | N | Q | T |
Query Conservation |   |
|   |
|
|
|
|
|
|
|
| . | . | . | . |
|
|   |   |
|   |   |
|
|
|
|   |
|
|   |   |   |   |   |   |
|
|   |   |   |
|
|
|
|
|   |   |   |
|   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |
|
|
|
|   |   |
|   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   | . | . | . | . | . |   |   |   |   |
|   |   |
|
|   |   |
|   |   |   |
|   |
Template Sequence |   |
K | E | A | N | G | W | F | V | G | Y | V | E | T | K | D | N | T | Y | Y | F | A | T | H | L | K | G | E | D | N | A | . |
. |
. |
. |
. |
N | G | E | K | A | Q | Q | I | S | E | R | I | L | K | E | M | E |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  | S | S |
|  |  |  |  |  |  |  |  |  |
| S | S |
| B | . | . | . | . | . | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
Template Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
| . | . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
537 | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | |
|
|
|
|
. | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . |
  |