|   |
45 | . | . | . | . | 50 | . | . | . | . | . | . | . | . | |
|
|
. | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | |
. | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 |
Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |  |  | . | . | . |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  | . |
|
|
|
|
|  |  |
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | L | R | H | F | E | E | T | D | D | A | Y | V | A | . |
. |
. |
G | N | Q | I | Q | I | M | S | Q | V | S | G | S | V | T | K | V | W | . |
A | D | N | T | D | F | V | K | E | G | D | V | L | V | T | L | D | P | T | D | A | R | Q | A | F | E | K | A | K | T | A | L | A | S | S | V | R | Q | T | H | Q | L | M | I |
Query Conservation |   |
  |   |   |   |   |   |   |
|   |   |   |   |
|   | . | . | . |   |   |   |
|   |
|   |
|   |
|   |
|   |
|   |   |
|   | . |
|   |
|
|
|   |
|   |
|
|
|   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |
|   |
|   |   |
|   |   |
|   |   |
|   |   |
|   |
|
|   |   |
|   |   |
|   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Sequence |   |
G | P | L | T | F | A | Q | S | F | P | A | N | V | S | Y | N | E | Y | Q | Y | A | I | V | Q | A | R | A | A | G | F | I | D | K | V | Y | P | L | T | V | G | D | K | V | Q | K | G | T | P | L | L | D | L | T | I | P | D | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |  |
|
| B |
| T | T |
|  |  |  |  |  |  |  | S |
|  |  |  |  |
|
|
| S |
|
| S | S |
|
|  |  | T | T |
|
|
|  |  |  |  |
|  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
 |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
102 | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |
  |   |
121 | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
N | S | K | Q | L | Q | A | N | I | E | V | Q | K | I | A | L | A | K | A | Q | S | D | Y | N | R | R | V | P | L | G | N | A | N | L | I | G | R | E | E | L | Q | H | A | R | D | A | V | T | S | A | Q | A | Q | L | D | V | A | I | Q | Q | Y | N | A | N | Q | A | M | I | L | G | T | K | L | E | D | Q | P | A | V | Q |
Query Conservation |   |
  |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
. |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Sequence |   |
. |
W | V | E | A | Q | S | E | Y | L | L | L | R | E | T | G | G | T | A | T | Q | T | E | G | I | L | E | R | L | R | L | A | G | M | P | E | A | D | I | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
. |  |  |  |  |  |  |  |  |  |  |  |  |  | S |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
|  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
. |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
158 | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |
  |   |
201 | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Q | A | A | T | E | V | R | N | A | W | L | A | L | E | R | T | R | I | I | S | P | M | T | G | Y | V | S | R | R | A | V | Q | P | G | A | Q | I | S | P | T | T | P | L | M | A | V | V | P | A | T | N | M | W | V | D | A | N | F | K | E | T | Q | I | A | N | M | R | I | G | Q | P | V | T | I | T | T | D | I | Y | G |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |
|   |
|   |
|   |   |   |
|   |   |   |
|   |   |
|
|   |
|   |
|   |   |
|
|   |
|
Alig confidence |   |
. | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . | . |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |   |
|   |
|   |   |   |   |   |   |   |
|   |   |
|   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |
|   |   |
|   |
|   |   |   |   |   |   |
Template Sequence |   |
. |
. |
. |
R | R | L | I | A | T | Q | K | I | Q | T | R | F | T | L | K | A | P | I | D | G | V | I | T | A | F | D | L | R | A | G | M | N | I | A | K | D | N | V | V | A | K | I | Q | G | M | D | P | V | W | V | T | A | A | I | P | E | S | I | A | W | L | V | K | D | A | S | Q | F | T | L | T | V | P | A | R | P |
Template Known Secondary structure |   |
. | . | . |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
| S | S |  |  |  |  | S |
|
|
|
|
| S | S |
|  |  |
| S |  |  |  |  |  |  |  |  |
|
| S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| G | G | G |  |  |  |  |
| S | S |
|
|
Template Predicted Secondary structure |   |
. | . | . |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
196 | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . |
  |
  |   |
281 | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 |
Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
D | D | V | K | Y | T | G | K | V | V | G | L | D | M | G | T | G | S | A | F | S | L | L | P | A | Q | N | A | T | G | N | W | I | K | V | V | Q | R | L | P | V | R | I | E | L | D | Q | K | Q | L | E | Q | Y | P | L | R | I | G | L | S | T | L | V | S | V | N | T | T | N | R | D | G | Q | V | L | A | N | K | V | R |
Query Conservation |   |
  |   |   |   |   |   |
|   |
|   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|   |   |   |   |   |   |   |   |   |
|   |
|
|
|   |
|   |
|   |
|   |   |   |   |   |   |   |   |   |
|
|   |   |
|
|
Alig confidence |   |
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   | . |   |   |
|   |
|   |   |
|   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|
|
Template Sequence |   |
D | K | T | . |
L | T | I | R | K | W | T | L | L | P | G | V | D | A | A | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
T | R | T | L | Q | L | R | L | E | V | D | N | A | D | E | A | . |
. |
. |
L | K | P | G | M | N | A | W | L | Q | L | N | T | A | S | E | P | M | L | L | I | P | S | Q | A | L |
Template Known Secondary structure |   |
| S |
| . |
|
|  |  |  |  |  |  |  |  |  |  |  | T | T | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | T | T |  |  |  |  |  |  |  |  |  |
|
| S | S |
| . | . | . |
|
| T | T |
|  |  |  |  |  |  |  |  |
|
| S |
|
|  |  |  |
| G | G | G |
|
Template Predicted Secondary structure |   |
|  |  | . |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
| . | . | . |
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |
|  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
273 | . | . | |
. | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | |
|
|
. | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . |
  |
  |   |
361 | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | |
. | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 |
Predicted Secondary structure |   |
 |  |
|
|
|
|
|  |  |  |  |  |
|
|
| . |
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
S | T | P | V | A | V | S | T | A | R | E | I | S | L | A | . |
P | V | N | K | L | I | D | D | I | V | K | A | N | A | G |
Query Conservation |   |
  |   |   |   |   |   |   |   |
|   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |   |   |   |   |
Template Sequence |   |
I | D | T | G | S | E | Q | R | V | I | T | V | D | A | D | G | R | F | V | P | K | R | V | A | V | F | Q | A | S | Q | G |
Template Known Secondary structure |   |
B |
| S | S | S |
|
|  |  |  |  |  |
| S | S | S |
|  |  |  |  |  |
|  |  |  |  |  |  | T | T |
Template Predicted Secondary structure |   |
 |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
333 | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . |
  |