|   |
162 | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . |
Predicted Secondary structure |   |
|  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
D | Q | E | V | R | Y | R | Q | R | Y | L | D | L | I | A | N | D | K | S | R | Q | T | F | V | V | R | S | K | I | L | A | A | I | R | Q | F | M | V | A | R | G | F | M | E | V | E | T | P | M | M | Q | V | I | P | G | G | A | S | A | R | P | F | I | T | H | H | N | A | L | D | L | D | M | Y | L | R | I | A | P | E |
Query Conservation |   |
  |   |
|   |
|   |   |   |
|   |
|
|
|   |
|   |   |   |   |   |   |   |
|   |   |
|
|   |
|   |   |   |
|
|   |
|
|   |   |   |
|
|   |
|
|
|
|
|
|
|   |   |   |   |   |
|   |   |
|   |   |
|   |
|   |   |   |   |   |   |   |   |   |
|
|   |   |
|
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |
|
|   |   |
|   |
|
|
|   |
|   |   |   |   |   |   |   |
|   |
|
|   |   |
|   |   |   |
|
|   |   |
|   |   |   |
|
|   |
|
|   |
|
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |
|   |   |
|   |   |
Template Sequence |   |
D | Q | E | V | R | Y | R | Q | R | Y | L | D | L | I | A | N | D | K | S | R | Q | T | F | V | V | R | S | K | I | L | A | A | I | R | Q | F | M | V | A | R | G | F | M | E | V | E | T | P | M | M | Q | V | I | P | G | G | A | S | A | R | P | F | I | T | H | H | N | A | L | D | L | D | M | Y | L | R | I | A | P | E |
Template Known Secondary structure |   |
| T | T |  |  |  |  | T |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T |
|  |  |
|
|
|
| S |  |  | S | S |
|
| S | S |
|
|
|
|
|  |  |  |  | T | T | T | T |  |  |  |  |  |
| S |
| S |  |
Template Predicted Secondary structure |   |
|  |  |  |  |
|
|
|
|  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
161 | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 |
  |
  |   |
242 | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | Y | L | K | R | L | V | V | G | G | F | E | R | V | F | E | I | N | R | N | F | R | N | E | G | I | S | V | R | H | N | P | E | F | T | M | M | E | L | Y | M | A | Y | A | D | Y | H | D | L | I | E | L | T | E | S | L | F | R | T | L | A | Q | E | V | L | G | T | T | K | V | T | Y | G | E | H | V | F | D | F | G |
Query Conservation |   |
|   |
|
|   |
|
|
|   |
|   |   |
|
|
|
|
|   |   |   |
|
|   |
|   |   |   |   |   |
|   |
|
|
|
|   |
|
|   |
|   |
|
|   |
|   |   |
|   |
|   |   |   |
|   |
|
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |
|
|
|   |
|   |   |   |   | . |
|   |
|
|
|   |
|   |
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
L | Y | L | K | R | L | V | V | G | G | F | E | R | V | F | E | I | N | R | N | F | R | N | E | G | I | S | V | . |
H | N | P | E | F | T | M | M | E | L | Y | M | A | Y | A | D | Y | H | D | L | I | E | L | T | E | S | L | F | R | T | L | A | Q | E | V | L | G | T | T | K | V | T | Y | G | E | H | V | F | D | F | G |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  | T |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
| . |
|
| S |  |  |  |  |  |  |  |  |  |  | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S | S | S |  |  |  |  | T | T |  |  |  |  | T | T |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
| . |
|
|  |  |
|
|
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |
|
|  |  |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
241 | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | |
. | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . |
  |
  |   |
322 | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . |
Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|  |  |
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
K | P | F | E | K | L | T | M | R | E | A | I | K | K | Y | R | P | E | T | D | M | A | D | L | D | N | F | D | A | A | K | A | L | A | E | S | I | G | I | T | V | E | K | S | W | G | L | G | R | I | V | T | E | I | F | D | E | V | A | E | A | H | L | I | Q | P | T | F | I | T | E | Y | P | A | E | V | S | P | L | A |
Query Conservation |   |
  |
|
|   |
|   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |
|
|   |
|   |
|   |   |   |   |
|
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |
Template Sequence |   |
K | P | F | E | K | L | T | M | R | E | A | I | K | K | Y | R | P | E | T | D | M | A | D | L | D | N | F | D | A | A | K | A | L | A | E | S | I | G | I | T | V | E | K | S | W | G | L | G | R | I | V | T | E | I | F | D | E | V | A | E | A | H | L | I | Q | P | T | F | I | T | E | Y | P | A | E | V | S | P | L | A |
Template Known Secondary structure |   |
S |
|
|  |  |  |  |  |  |  |  |  |  |  |  | S | T | T |
|
| G | G | G | G | G | S |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
|
| T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  | T | G | G | G |
|
| S |
|  |  |  |  |
|
| B | G | G | G |
| T | T | B |
Template Predicted Secondary structure |   |
|
|
|  |  |
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|  |  |  |
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
321 | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 |
  |
  |   |
402 | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . |
Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | R | N | D | V | N | P | E | I | T | D | R | F | E | F | F | I | G | G | R | E | I | G | N | G | F | S | E | L | N | D | A | E | D | Q | A | E | R | F | Q | E | Q | V | N | A | K | A | A | G | D | D | E | A | M | F | Y | D | E | D | Y | V | T | A | L | E | Y | G | L | P | P | T | A | G | L | G | I | G | I | D | R |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |
|   |
|   |
|
|   |   |
|   |   |
|   |   |
|   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|
|   |
|
|   |   |
|   |
|
|
|
|
|   |
|
|
|
|
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |
|   |
|
|   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|   |
|
|   |   |   |   |   |
|   |   |
|   |   |
|
|
|
|
|
|
|
|
Template Sequence |   |
R | R | N | D | V | N | P | E | I | T | D | R | F | E | F | F | I | G | G | R | E | I | G | N | G | F | S | E | L | N | D | A | E | D | Q | A | E | R | F | Q | E | Q | V | N | A | K | A | A | G | D | D | E | A | M | F | Y | D | E | D | Y | V | T | A | L | E | Y | G | L | P | P | T | A | G | L | G | I | G | I | D | R |
Template Known Secondary structure |   |
| B |
| S | S |
| T | T | B | B | S |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  | B |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| T | T |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
| S |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
401 | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 |
  |
  |   |
482 | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
M | I | M | L | F | T | N | S | H | T | I | R | D | V | I | L | F | P | A | M | R | P |
Query Conservation |   |
|
|
|
|
|   |
|   |   |   |
|
|
|
|
|   |
|
|   |   |
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |   |
|   |   |   |   |   |
|
|
|
|   |   |
|
|   |   |   |   |
Template Sequence |   |
M | I | M | L | F | T | N | S | H | T | I | R | D | V | I | L | F | P | A | M | R | P |
Template Known Secondary structure |   |
 |  |  |  |  |  | T |
| S | S | G | G | G | T | S | S | S |
|
|
|
|
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
481 | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . |
  |