|   |
188 | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | |
|
|
|
. | . | . | . | . | . | 260 | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
| . | . | . | . |
|  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
S | K | I | L | A | A | I | R | Q | F | M | V | A | R | G | F | M | E | V | E | T | P | M | M | Q | V | I | P | G | G | A | S | A | R | P | F | I | T | H | H | N | A | L | D | L | D | M | Y | L | R | I | A | P | E | L | Y | L | K | R | L | V | V | G | G | F | E | . |
. |
. |
. |
R | V | F | E | I | N | R | N | F | R |
Query Conservation |   |
|   |
|   |   |   |
|
|   |
|
|   |   |   |
|
|   |
|
|
|
|
|
|
|   |   |   |   |   |
|   |   |
|   |   |
|   |
|   |   |   |   |   |   |   |   |   |
|
|   |   |
|
|
|
|   |
|
|   |
|
|
|   |
|   |   | . | . | . | . |
|
|
|
|
|   |   |   |
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|
|
|   |   |
|
|   |
|
|   |   |
|
|
|   |   |
|
|
|   |
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |
|   |
|
|
|
|
|
|
|
|
|   |   |
|
|
|   |
|
|
|   |   |   |
|   |   |   |
|   |   |   |   |
|
|
|
|
|
Template Sequence |   |
A | E | I | R | Q | A | F | L | D | F | F | H | S | K | G | H | Q | V | V | A | S | S | S | L | V | P | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
H | N | D | P | T | L | L | F | T | N | A | G | M | N | Q | F | K | D | V | F | L | G | L | D | K | R | N | Y | S | R | A | T | T | S | Q | R | C | V | R |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |
|
|
|
|
| S | S |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | T | T |
| S | S |
| S | S |
|
| S | T | T | G | G | G |  |  |  |  |  | T | S | S |
|
| S |
| S |  |  |  |  |  |  |  |  |  |
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
5 | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . |
  |
  |   |
|
|
|
|
|
|
|
|
|
264 | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . |
Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
N | E | G | I | S | V | R | H | N | P | E | F | T | M | M | E | L | Y | M | A | Y | A | D | Y | H | D | L | I | E | L | T | E | S | L | F | R | T | L | A | Q | E | V | L | G | T | T | K | V | T | Y | G | E | H | V | F | D | F | G | K | P | F | E | K | L | T | M | R | E | A | I | K |
Query Conservation |   |
. | . | . | . | . | . | . | . | . |   |
|   |   |   |   |   |
|   |
|
|
|
|   |
|
|   |
|   |
|
|   |
|   |   |
|   |
|   |   |   |
|   |
|
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |
|   |   |   |   |
|
|   |   |
Alig confidence |   |
. | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |
|
|
|
|
|
|
|
|
|
|
|   |
|   |
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
| . | . | . | . | . |
|
|   |
|
|
|   |   |
|
|
|
|
|
|   |   |   |   |
|   |
|   |   |   |
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Sequence |   |
A | G | G | K | H | N | D | L | E | N | V | G | Y | T | A | R | H | H | T | F | F | E | M | L | G | . |
N | F | S | F | G | D | Y | . |
. |
. |
. |
. |
F | K | L | D | A | I | L | F | A | W | L | L | L | T | S | E | K | W | F | A | L | P | K | E | R | L | W | V | T | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
 |  | T | T |  |  |
| T | T | T | T | T | T | S | S | S |
|
| S |  |  |  |  |  |  | . |  |  |  | S | S | S |
| . | . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |
| T | T | T | T |
|
|
| G | G | G |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  | . |  |  |  |  |  |  |  | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |
|
|
|
|  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | |
. | . | . | . | . | 100 | . | |
|
|
|
|
. | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | |
|
|
|
|
|
|
|
|
|
|
|
|
  |
  |   |
335 | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | |
|
|
|
|
. | 390 | . | . | . |
Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  | . | . | . | . | . |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
Query Sequence |   |
K | Y | R | P | E | T | D | M | A | D | L | D | N | F | D | A | A | K | A | L | A | E | S | I | G | I | T | V | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
E | K | S | W | G | L | G | R | I | V | T | E | I | F | D | E | V | A | E | A | H | L | I | Q | P | T | . |
. |
. |
. |
. |
F | I | T | E | Y |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   | . | . | . | . | . |
|
|   |
|   |
Alig confidence |   |
. | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
| . | . | . | . | . |
|
|
|
|
|
Template Conservation |   |
. | . | . | . | . | . | . | . |
|   |   |   |
|   |
|
|   |   |
|
|   |   |   |   |
|
|   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |
|
|
|
|
|   |   |
|   | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |
|
|
|
|
|
|
|
|
|   |
|
|   |
Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
V | Y | E | S | D | D | E | A | Y | E | I | W | E | K | E | V | G | I | P | R | E | R | I | I | R | I | G | D | N | K | G | A | P | Y | A | S | D | N | F | W | Q | M | G | D | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
T | G | P | C | G | P | C | T | E | I | F | Y | D | H |
Template Known Secondary structure |   |
. | . | . | . | . | . | . | . |  |  | T | T |
|  |  |  |  |  |  |  |  |  | T | T |
|
|
| G | G | G |  |  |  |  |
| S | T | T | S | S | T | T |
| B | T | T |  |  |
| S | S | S | . | . | . | . | . | . | . | . | . | . | . | . | . | . | S |  |  |  |  |  |  |  |  |  |  |  |  |
|
Template Predicted Secondary structure |   |
. | . | . | . | . | . | . | . |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
|
|
131 | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | 180 | . | . | . | . | . | . | . | . |
  |
  |   |
394 | . | . | . | |
|
. | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . |
Predicted Secondary structure |   |
|  |  |
| . | . |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
Query SS confidence |   |
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
P | A | E | V | . |
. |
S | P | L | A | R | R | N | D | V | N | P | E | I | T | D | R | F | E | F | F | I | G | G | R | E | I | G | N | G | F | S | E | L | N | D | A | E | D | Q | A | E | R | F | Q | E | Q | V | N | A | K | A | A | G | D | D | E | A | M | F | Y | D | E | D | Y | V | T | A | L | E | Y | G | L | P | P |
Query Conservation |   |
|   |   |   | . | . |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |
|   |
|   |
|
|   |   |
|   |   |
|   |   |
|   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|
|   |
|
|   |   |
|   |
|
|
Alig confidence |   |
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |
|
Template Conservation |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|   |   |   |   |
|
|   |
|   |
|
|
|   | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
Template Sequence |   |
G | D | H | I | W | G | G | P | P | G | S | P | E | E | D | G | D | R | Y | I | E | I | W | N | I | V | F | M | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Q | F | N | R | Q | A | D | G | T | M | E | P | L | P | K | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
P |
Template Known Secondary structure |   |
| T | T | S |
|
|
|
| T | T | S | T | T | T | T | S | S | S |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |
| T | T | S |
|  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
189 | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | |
|
|
|
|
|
|
|
|
|
|
|
|
. |
  |
  |   |
472 | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|  |  |  |  |
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | A | G | L | G | I | G | I | D | R | M | I | M | L | F | T | N | S | H | T | I | R | D | V | I | L | F |
Query Conservation |   |
|
|
|   |
|
|
|
|
|
|
|
|
|
|
|   |
|   |   |   |
|
|
|
|
|   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|
|
|
|
|
|
|
|
|
|   |   |
|
|
|
|   |   |
|   |
|
|
|
|
|
|
Template Sequence |   |
S | V | D | T | G | M | G | L | E | R | I | A | A | V | L | Q | H | V | N | S | N | Y | D | I | D | L | F |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| S | S | G | G | G | S |  |  |  |
Template Predicted Secondary structure |   |
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
233 | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . |
  |