|   |
2 | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . |
Predicted Secondary structure |   |
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
K | H | D | H | F | V | V | Q | S | P | D | K | P | A | Q | Q | L | L | L | L | F | H | G | V | G | D | N | P | V | A | M | G | E | I | G | N | W | F | A | P | L | F | P | D | A | L | V | V | S | V | G | G | A | E | P | S | G | N | P | A | G | R | Q | W | F | S | V | Q | G | I | T | E | D | N | R | Q | A | R | V | D |
Query Conservation |   |
  |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |
|
|   |
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |
|   |
|   |   |   |   |
|   |
|
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |
|   |   | . |
|   |   | . |   |   |   |
|   |   |   |
|   |
|
|   |
|   |
|   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |
Template Sequence |   |
P | S | T | S | V | V | L | Q | G | L | P | M | V | A | R | K | T | L | F | M | L | P | D | G | G | G | S | A | F | S | Y | A | S | L | P | R | . |
L | K | S | . |
D | T | A | V | V | G | L | N | C | P | Y | A | R | D | P | E | N | M | N | C | T | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
H | G |
Template Known Secondary structure |   |
|
|  |  |  |  |  |  | S |
| T | T | T | S | S |  |  |  |  |  |  |
|
| T | T |
|
| G | G | G | G | T | T | S |
|
| . |
| S | S | . | S |  |  |  |  |  |  |  |
| T | T | T | T |
| G | G | G |
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  | . |
|
|
| . |
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1851 | . | . | . | . | . | . | . | . | 1860 | . | . | . | . | . | . | . | . | . | 1870 | . | . | . | . | . | . | . | . | . | 1880 | . | . | . | . | . | . | |
. | . | . | |
1890 | . | . | . | . | . | . | . | . | . | 1900 | . | . | . | . | . | . | . | . | . | 1910 | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . |
  |
  |   |
82 | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Sequence |   |
A | I | M | P | T | F | I | E | T | V | R | Y | W | Q | K | Q | S | G | V | G | A | N | A | T | A | L | I | G | F | S | Q | G | A | I | M | V | L | E | S | I | K | A | E | P | G | L | A | S | R | V | I | A | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |
|   |
|   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . |   |   |   |   |
|   |
|
|
|   |
|
|   |
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
A | M | I | E | S | F | C | N | E | I | R | R | R | Q | P | R | . |
. |
. |
. |
. |
G | P | Y | H | L | G | G | W | S | S | G | G | A | F | A | Y | V | V | A | E | A | L | V | N | Q | G | E | E | V | H | S | L | I | I | I | D | A | P | I | P | Q | A | M | E | Q | L | P | R | A | F | Y | E | H | C | N | S | I | G | L |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |
| S | S | . | . | . | . | . |
|
|  |  |  |  |  |  | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |  |  |  |  |  | S |
|
| S | S |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  | T | T | T |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . | . | . | . |
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1913 | . | . | . | . | . | . | 1920 | . | . | . | . | . | . | . | . | |
|
|
|
|
. | 1930 | . | . | . | . | . | . | . | . | . | 1940 | . | . | . | . | . | . | . | . | . | 1950 | . | . | . | . | . | . | . | . | . | 1960 | . | . | . | . | . | . | . | . | . | 1970 | . | . | . | . | . | . | . | . | . | 1980 | . | . | . | . | . | . | . |
  |
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
134 | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . |
Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
F | N | G | R | Y | A | S | L | P | E | T | A | S | T | A | T | T | I | H | L | I | H | G | G | E | D | P | V | I | D | L | A |
Query Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |
|
|   |   |
|   |   |
|
|   |   |
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
F | A | T | Q | P | G | A | S | P | D | G | S | T | E | P | P | S | Y | L | I | P | H | F | T | A | V | V | D | V | M | L | D | Y | K | L | A | P | L | H | A | R | R | M | P | K | V | G | I | V | W | A | A | D | T | V | M | D | E | R | D | A | P | K | M | K | G | M | H | F | M | I | Q | K | R | T | E | F | G | P | D |
Template Known Secondary structure |   |
T | T | T | S | S | S | S |
| S | S | S |
| S |
|
|
| T | T |  |  |  |  |  |  |  |  |  |  |  | T | T | T |
|
|
|
|
|
|
|
| S | S |
|
|  |  |  |  |  |  |  |  |  |
| S | S |
| T | T | T | S |
|
|
| S | S |
|
| T | T | T | S |
|
|
|
|
| S |
| T |
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1988 | . | 1990 | . | . | . | . | . | . | . | . | . | 2000 | . | . | . | . | . | . | . | . | . | 2010 | . | . | . | . | . | . | . | . | . | 2020 | . | . | . | . | . | . | . | . | . | 2030 | . | . | . | . | . | . | . | . | . | 2040 | . | . | . | . | . | . | . | . | . | 2050 | . | . | . | . | . | . | . | . | . | 2060 | . | . | . | . | . | . | . |
  |
  |   |
166 | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | |
|
. | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
| . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
H | A | V | A | A | Q | E | A | L | I | S | A | G | G | D | V | T | L | D | I | V | E | D | L | G | H | A | . |
. |
I | D | N | R | S | M | Q | F | A | L | D | H | L | R | Y | T | I | P |
Query Conservation |   |
  |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |
|
|   | . | . |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   | . | . | . | . | . |   |   |   |   |   |   |   |   |
|   |
|   |
|
|   |   |   |
|
|   |
|   |   |   |   |
|
|   |   |
|   |   |
|
|
|
Template Sequence |   |
G | W | D | T | I | M | P | . |
. |
. |
. |
. |
G | A | S | F | D | I | V | R | A | D | G | A | N | H | F | T | L | M | Q | K | E | H | V | S | I | I | S | D | L | I | D | R | V | M | A |
Template Known Secondary structure |   |
T |  |  |  |  | S | T | . | . | . | . | . | T |
|
|  |  |  |  |  |  |  |  |  |  | T | T | G | G | G | S | T | T | T | T |  |  |  |  |  |  |  |  |  |  | T |
|
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
| . | . | . | . | . |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
2068 | . | 2070 | . | . | . | . | |
|
|
|
|
. | . | . | . | . | 2080 | . | . | . | . | . | . | . | . | . | 2090 | . | . | . | . | . | . | . | . | . | 2100 | . | . | . | . | . | . | . | . | . |
  |