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Job DescriptionP0A955
Confidence97.26%DateThu Jan 5 11:09:25 GMT 2012
Rank227Aligned Residues154
% Identity19%Templatec2cw6B_
PDB info PDB header:lyaseChain: B: PDB Molecule:hydroxymethylglutaryl-coa lyase, mitochondrial; PDBTitle: crystal structure of human hmg-coa lyase: insights into2 catalysis and the molecular basis for3 hydroxymethylglutaric aciduria
Resolution2.10 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   25....30.........40.........50. ........60.........70.........80.........90...
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Query Sequence  KLEHAVPMAKALVAGGVRVLEVTLRTE. . . . . . . . CAVDAIRAIAKEVPEAIVGAGTVLNPQQLAEVTEAGAQFAIS. . .
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Template Sequence  STPVKIKLIDMLSEAGLSVIETTSFVSPKWVPQMGDHTEVLKGIQKFPGINYPVL. . TPNLKGFEAAVAAGAKEVVIFGA
Template Known Secondary structure 
TT
S




TTT
GGGTTS


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B

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STT
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   52.......60.........70.........80.........90.........100...... ...110.........120.........
 
   94.....100.........110..... ....120 .........130... ....
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Query Sequence  . . . . . . . . . . . . . . . . . PGLTEPLLKAATEGTIPLIPGI. . . . . . . . . . . STVSE. . . . LMLGMDYGLKEFK. . . . FFPA
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Template Sequence  ASELFTKKNINCSIEESFQRFDAILKAAQSANISVRGYVSCALGCPYEGKISPAKVAEVTKKFYSMGCYEISLGDTIGVG
Template Known Secondary structure  S
TSS
TTTTT
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BTTTBS

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   130.........140.........150.........160.........170.........180.........190.........200.........
 
   138.140.........150......... 160.........170.........180
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Query Sequence  EANGGVKALQAIAGPFSQVRFC. . . . PTGGISPANYRDYLALKSVLC
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Template Sequence  TPGIMKDMLSAVMQEVPLAALAVHCHDTYGQALANTLMALQMGVSVV
Template Known Secondary structure 
S
GGGB
TTS
TT

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   210.........220.........230.........240.........250......
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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