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Job DescriptionP25524
Confidence100.00%DateThu Jan 5 11:41:56 GMT 2012
Rank13Aligned Residues378
% Identity15%Templatec2vr2A_
PDB info PDB header:hydrolaseChain: A: PDB Molecule:dihydropyrimidinase; PDBTitle: human dihydropyrimidinase
Resolution2.80 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   8.10.........20. ........30.........40.........50.........60.........70........ .80.
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Query Sequence  TIINARLPGEEGLW. . QIHLQDGKISAIDAQSGVMPITENSLDAEQGLVIPPFVEPHIHLDTTQTAGQPNWNQ. . . . SGT
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Template Sequence  LIRGGRVVNDDFSEVADVLVEDGVVRALG. . . . . . . . HLRVLDAAGKLVLPGGIDTHTHMQFPFMGSRSIDDFHQGTKAA
Template Known Secondary structure  S

SS

TT........


TTS

TT
B
SSSB
S

TT
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   8.10.........20.........30...... ...40.........50.........60.........70.........
 
   82.......90.........100.........110.........120.........130.........140.........150.........160.
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Query Sequence  LFEGIERWAERKALLTHDDVKQRAWQTLKWQIANGIQHVRTHVDVSDATLTALKAMLEVKQEVAPWIDLQIVAFPQEGIL
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Template Sequence  LSGGTTMIIDFAIPQKGGSLIEAFETWRSWADPKVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMV
Template Known Secondary structure  TTT


TT

TTT
SS
S
STS


SSSTTTTB
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   91........100.........110.........120.........130.........140.........150.........160.........170
 
   162.......170.........180.........190.........200.........210.........220.........230.........240.
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Query Sequence  SYPNGEALLEEALRLGADVVGAIPHFEFTREYGVESLHKTFALAQKYDRLIDVHCDEIDDEQSRFVETVAALAHHEGMGA
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Template Sequence  TDLELYEAFSRCKEIGAIAQVH. . . . . . . . AENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNC
Template Known Secondary structure 
T
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S
TT

STTS
T
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   171........180.........190.. .......200.........210.........220.........230.........240..
 
   242.......250.........260.........270.........280.........290 .........300....
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Query Sequence  RVTASHTTAMHSYNGAYTSRLFRLLKMSGINFVANPLVNIHLQGRFDTY. . . . . . . . . . . . . . . . . PKRRGITRVKEMLE
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Template Sequence  PLYIVHVM. . . . . . SKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPPLRPDPSTPDFLMNLLA
Template Known Secondary structure 

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TT

B

SGGGG
SSTT

SS


S
TT
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   243......250 .........260.........270.........280.........290.........300.........310......
 
   305....310........ .320.........330.........340.........350.........360...... ...370
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Query Sequence  SGINVCFGHDDVFD. . . . . . . . . . . . PWYPLGTANMLQVLHMGLHVCQLMGYGQINDGLNLITHHSARTLNLQD. . YGIA
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Template Sequence  NDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWEKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIA
Template Known Secondary structure  TTSS


B

B



GGGSS
GGGS


B

TTTTTTTSS
TTT
TTTSS

S
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   317..320.........330.........340.........350.........360.........370.........380.........390......
 
   371........380.... .....390.........400.......
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Query Sequence  AGNSANLIILPAEN. . . . . . . . . . . . . . . . GFDALRRQVPVRYSVRGGKVIAS
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Template Sequence  VGSDADIVIWDPKGTRTISAKTHHQAVNFNIFEGMVCHGVPLVTISRGKVVYE
Template Known Secondary structure  TTSB



TTT
SSS
S

TTTT
TT
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   397..400.........410.........420.........430.........440.........
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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