|   |
2 | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
. | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
Query Sequence |   |
S | K | R | Y | F | V | T | G | T | D | T | E | V | G | K | T | V | A | S | C | A | L | L | Q | A | A | K | . |
. |
. |
. |
. |
. |
A | A | G | Y | R | T | A | G | Y | K | P | V | A | S | G | S | E | K | T | P | E | G | L | R | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
N | S | D | A | L |
Query Conservation |   |
  |
|   |
|   |
|   |
|   |   |
|
|
|
|
|
|
|
|
|   |   |
|
|   |   |
|
| . | . | . | . | . | . |   |   |
|   |   |
|
|   |
|
|   |
|   |   |
|   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
Template Conservation |   |
  |   |
|
|
|
|   |
|   |
|
|
|
|
|
|
|
|   |
|   |   |
|
|   |   |
|
|   |   |   |   |   |   |   |   |
|   |
|
|
|
|
|
|   |
|
|
|   |
|
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
A | Y | V | I | F | I | S | N | L | K | G | G | V | S | K | T | V | S | T | V | S | L | A | H | A | M | R | A | H | P | H | L | L | M | E | D | L | R | I | L | V | I | D | L | D | P | Q | S | S | A | T | M | F | L | S | H | K | H | S | I | G | I | V | N | A | T | S | A | Q | A | M | L | Q | N | V | S | R | E | E | L |
Template Known Secondary structure |   |
|  |  |  |  |  |
|
| S | S | S | S | S | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| T | T | T | G | G | G |
|
|
|  |  |  |  |  |
|
| T | T |
|  |  |  |  |  |  | S |
| T | T | T | T |
| S |
| S | S |
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
108 | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . |
  |
  |   |
58 | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | |
|
|
|
|
. | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | L | Q | R | N | S | S | L | Q | L | D | Y | A | T | V | N | P | Y | T | . |
. |
. |
. |
. |
F | A | E | P | T | S | P | H | I | I | S | A | Q | E | G | R | P | I | E | S | L | V | M | S | A | G | L | R | A | L | E | Q | Q | A | D | W | V | L | V | E | G | A | G | G | W | F | T | P | L | S | D | T | F | T | F | A |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |
|   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |   |
|   |   |
|   |   |   |   |
|
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |
|
|   |
|
|
|
|   |
|
|   |
|   |   |   |
|   |   |
|
|   |
|
|
Template Sequence |   |
L | E | E | F | I | V | P | S | V | V | P | G | V | D | V | M | P | A | S | I | D | D | A | F | I | A | S | D | W | R | E | L | C | N | E | H | L | P | G | Q | N | I | H | A | V | L | K | E | N | V | I | D | K | L | K | S | D | Y | D | F | I | L | V | D | S | G | P | H | L | D | A | F | L | K | N | A | L | A | S | A |
Template Known Secondary structure |   |
 |  |  | T |
|  |  |
| S | S | T | T |  |  |  |  |
|
|
| T | T |  |  |  |  |  |  | T |  |  |  |  |  |  |  |  | S | T | T | S |
| T | T | S |  |  |  |  |  | T |  |  |  |  | T | T | T |
| S |  |  |  |  |  |
|
| S |
|
| S |  |  |  |  |  |  |  |  |  |
|
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
188 | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . |
  |
  |   |
133 | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
. | . | . | . | 170 | . | . | . | . | . | . | . | . | . | |
180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | |
Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . |  |
|
|
|
|  |  |  |  |  |  |
|
|
| . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
Query Sequence |   |
D | W | V | T | Q | E | Q | L | P | V | I | L | V | V | G | V | K | L | G | C | I | N | H | A | M | L | T | A | Q | V | I | Q | H | . |
. |
. |
. |
. |
. |
. |
. |
. |
A | G | L | T | L | A | G | W | V | A | N | D | V | T | . |
P | P | G | K | R | H | A | E | Y | M | T | T | L | T | R | M | I | P | A | P | L | L | . |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |
|   |
|   |   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|
|
| . |
Alig confidence |   |
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
Template Conservation |   |
|   | . | . | . | . | . | . | . |
|
|
|
|   |   |
|   |   |   |
|   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
Template Sequence |   |
N | I | . |
. |
. |
. |
. |
. |
. |
L | F | T | P | L | P | P | A | T | V | D | F | H | S | S | L | K | Y | V | A | R | L | P | E | L | V | K | L | I | S | D | E | G | C | E | C | Q | L | A | T | N | I | G | F | M | S | K | L | S | N | K | A | D | H | K | Y | C | H | S | L | A | K | E | V | F | G | G | D | M | L | D |
Template Known Secondary structure |   |
S |  | . | . | . | . | . | . | . |  |  |  |  |  |
| S | S |  |  |  |  |  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  |  |  | T | S |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
| S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | G | G | G | B |
| S |
Template Predicted Secondary structure |   |
|  | . | . | . | . | . | . | . |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
268 | . | |
|
|
|
|
|
|
270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 |
  |
  |   |
202 | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 |
Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | E | I | P | W | L | A | E | N | P | E | N | A | A | T | G | K | Y | I |
Query Conservation |   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|
|   |
|   |   |
|   |   |
|   |   |   |   |   |
|
|
Template Sequence |   |
V | F | L | P | R | L | D | G | F | E | R | C | G | E | S | F | D | T | V |
Template Known Secondary structure |   |
S |
|  |  |
|
|  |  |  |  |  |  |  |  | T | T |
|
| T |
Template Predicted Secondary structure |   |
 |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
341 | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . |
  |