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Job DescriptionP25741
Confidence99.26%DateThu Jan 5 11:42:28 GMT 2012
Rank198Aligned Residues188
% Identity14%Templatec3o96A_
PDB info PDB header:transferaseChain: A: PDB Molecule:rac-alpha serine/threonine-protein kinase; PDBTitle: crystal structure of human akt1 with an allosteric inhibitor
Resolution2.70 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   16...20.........30.........40.........50.........60.........70.........80.........90.....
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Query Sequence  DAFAEVKKLNGEVFRELETRRTLRFELSGKSYFLKWHKGTTLKEIIKNLLSLRMPVLGADREWHAIHRLSDVGVDTMKGI
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Template Sequence  NEFEYLKLLGKGTFGKVI. . . LVKEKATGRYYAMKILKKE. . . . . . . . . . . . . . . . . . VIVANRVLQNSRHPFLTALKYS
Template Known Secondary structure  TSTT...TTT

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   148.150.........160..... ....170.........180.... .....190.........200......
 
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Query Sequence  GFGEKGLNPLTRASFIITEDLTPTISLEDYCADWAVNPPDIRVKRMLIARVATMVRKMHT. AGINHRDCYICHFLLHLPF
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Template Sequence  FQ. . . . . . . . THDRLCFVMEYANGGELFFHLSRERV. . FSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDG
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   217. .220.........230.........240.... .....250.........260.........270.........280......
 
   175....180.........190.........200.........210.........220.........230.........240.........250.
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Query Sequence  TGREDELKISVIDLHRAQIRAKVPRRWRDKDLIGLYFSSMNIGLTQRDIWRFMKVYFGMPLRKILSLEQNLLNMASV
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Template Sequence  HIKITDFGL. . . . . . . . . . . . . . . . . CKEPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFEL
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   287..290..... ....300.........310.........320.........330.........340......
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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