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Job DescriptionP25741
Confidence99.31%DateThu Jan 5 11:42:28 GMT 2012
Rank192Aligned Residues189
% Identity16%Templatec3mtfB_
PDB info PDB header:transferaseChain: B: PDB Molecule:activin receptor type-1; PDBTitle: crystal structure of the acvr1 kinase in complex with a 2-2 aminopyridine inhibitor
Resolution2.15 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   15....20.........30.........40.........50.........60.........70.........80.........90....
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Query Sequence  KDAFAEVKKLNGEVFRELETRRTLRFELSGKSYFLKWHKGTTLKEIIKNLLSLRMPVLGADREWHAIHRLSDVGVDTMKG
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Template Sequence  ARDITLLECVGKGRYGE. . . . . VWRGSWQGENVAVK. . . . . . . . . . . . IFSSRDEKSWFRETELYNTVMLRHENILGFIA
Template Known Secondary structure  TTTTT.....TT............
GGGS



TTB

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   205....210.........220. ........230..... ....240.........250.........260.......
 
   95....100.........110.........120.........130.........140.........150........ .160......
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Query Sequence  IGFGEKGLNPLTRASFIITEDLTPTISLEDYCADWAVNPPDIRVKRMLIARVATMVRKMHTAGI. . . . . . . . NHRDCYIC
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Template Sequence  SDMTSR. . . . HSSTQLWLITHYHEMGSLYDYLQL. . . TTLDTVSCLRIVLSIASGLAHLHIEIFGTQGKPAIAHRDLKSK
Template Known Secondary structure  ....TT

TT
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B
S
B
STT
B

S

SGG
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   268.270... ......280.........290....... ..300.........310.........320.........330.........340
 
   167..170.........180.........190.........200.........210.........220. ........230.
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Query Sequence  HFLLHLPFTGREDELKISVIDLHRAQIRAKVPRRWRDKDLIGLYFSSMNIGLTQR. . . . . . . . . . . DIWRFMKVYF
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Template Sequence  NILVKKNGQCCIADLGLAVMHSQSTNQLDVG. . . . NNPRVGTKRYMAPEVLDETIQVDCFDSYKRVDIWAFGLVLW
Template Known Secondary structure  G
TTS



TT
TTTT

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   341........350.........360.........370. ........380.........390.........400.........410..
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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