Return to main results Retrieve Phyre Job Id

Job DescriptionP25741
Confidence99.28%DateThu Jan 5 11:42:28 GMT 2012
Rank197Aligned Residues168
% Identity15%Templatec3k54A_
PDB info PDB header:transferaseChain: A: PDB Molecule:tyrosine-protein kinase btk; PDBTitle: structures of human bruton's tyrosine kinase in active and inactive2 conformations suggests a mechanism of activation for tec family3 kinases.
Resolution1.94 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   12. ......20.........30.........40.. .......50.........60.........70.........80.........
Predicted Secondary structure 
.











.














Query SS confidence 

.




























.














































Query Sequence  WR. GKDAFAEVKKLNGEVFRELETRRTLRFEL. SGKSYFLKWHKGTTLKEIIKNLLSLRMPVLGADREWHAIHRLSDVGV
Query Conservation 
 .  
 

 
  
 

       
   
   . 
     
           
             

   
  
    
Alig confidence 

.

















.....





.










...................
















Template Conservation    
          

 
 

 .....
 
        



 

...................    

  
  
 



Template Sequence  WEIDPKDLTFLKELGTGQFGV. . . . . VKYGKWRGQYDVAIKMIK. . . . . . . . . . . . . . . . . . . EFIEEAKVMMNLSHEKL
Template Known Secondary structure  GB

GGGSTTSS
.....TTT

...................

TT


TTB
Template Predicted Secondary structure 



.....



...................





Template SS confidence 















































































   395....400.........410..... ....420.........430... ......440.........450
 
   90.........100.........110.........120.........130.........140.........150.........160.........
Predicted Secondary structure 
































Query SS confidence 















































































Query Sequence  DTMKGIGFGEKGLNPLTRASFIITEDLTPTISLEDYCADWAVNPPDIRVKRMLIARVATMVRKMHTAGINHRDCYICHFL
Query Conservation       
               

   
     
           
       
       
  

  

 



   


Alig confidence 






........


























.




































Template Conservation 
      ........        
        
         .                                     
Template Sequence  VQLYGVC. . . . . . . . TKQRPIFIITEYMANGCLLNYLREMRH. RFQTQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCL
Template Known Secondary structure 

........
SSSS


TT
GGG.


TT


S

SGGG
Template Predicted Secondary structure 





........





















.
















Template SS confidence 















































































   458.460.... .....470.........480.........490. ........500.........510.........520........
 
   170.........180.........190.........200.........210.........220.........230.
Predicted Secondary structure 





































Query SS confidence 





























































Query Sequence  LHLPFTGREDELKISVIDLHRAQIRAKVPRRWRDKDLIGLYFSSMNIGLTQRDIWRFMKVYF
Query Conservation            
     

                  
  
            
   
   
 
Alig confidence 














...................



























Template Conservation          
 
    ...................                  

 
 
    
Template Sequence  VNDQGVVKVSDFGFP. . . . . . . . . . . . . . . . . . . VRWSPPEVLMYSKFSSKSDIWAFGVLMW
Template Known Secondary structure 
TT







...................GGG





Template Predicted Secondary structure 







...................





















Template SS confidence 





























































   529530.........540... ......550.........560.........570.
 
Download:Text version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
Disclaimer
Terms and Conditions