Job Description P25741 Confidence 99.46% Date Thu Jan 5 11:42:28 GMT 2012 Rank 158 Aligned Residues 188 % Identity 16% Template c3fupB_ PDB info PDB header:transferase Chain: B: PDB Molecule:tyrosine-protein kinase jak2; PDBTitle: crystal structures of jak1 and jak2 inhibitor complexes Resolution 2.40 Å

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		31	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.									.	.	.	.	60	.	.	.	.	.		.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.
Predicted Secondary structure																											.	.	.	.	.	.	.	.											.
Query SS confidence																											.	.	.	.	.	.	.	.											.
Query Sequence		E	L	E	T	R	R	T	L	R	F	E	L	S	G	K	S	Y	F	L	K	W	H	K	G	T	.	.	.	.	.	.	.	.	T	L	K	E	I	I	K	N	L	L	.	S	L	R	M	P	V	L	G	A	D	R	E	W	H	A	I	H	R	L	S	D	V	G	V	D	T	M	K	G	I	G	F	G	E	K	G
Query Conservation																											.	.	.	.	.	.	.	.											.
Alig confidence																											.	.	.	.	.	.	.	.											.																																				.
Template Conservation																																																																																	.
Template Sequence		Q	F	E	E	R	H	L	K	F	L	Q	Q	L	G	K	G	N	F	G	S	V	E	M	C	R	Y	D	P	L	Q	D	N	T	G	E	V	V	A	V	K	K	L	Q	H	S	T	E	E	H	L	R	D	F	E	R	E	I	E	I	L	K	S	L	Q	H	D	N	I	V	K	Y	K	G	V	C	Y	S	N	L	.
Template Known Secondary structure					G	G	G											S	S										T	T	S	S	S											S																			T				T	T	B												.
Template Predicted Secondary structure																																																																																	.
Template SS confidence
		843	.	.	.	.	.	.	850	.	.	.	.	.	.	.	.	.	860	.	.	.	.	.	.	.	.	.	870	.	.	.	.	.	.	.	.	.	880	.	.	.	.	.	.	.	.	.	890	.	.	.	.	.	.	.	.	.	900	.	.	.	.	.	.	.	.	.	910	.	.	.	.	.	.	.	.	.	920	.
		102	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.
Predicted Secondary structure
Query SS confidence
Query Sequence		L	N	P	L	T	R	A	S	F	I	I	T	E	D	L	T	P	T	I	S	L	E	D	Y	C	A	D	W	A	V	N	P	P	D	I	R	V	K	R	M	L	I	A	R	V	A	T	M	V	R	K	M	H	T	A	G	I	N	H	R	D	C	Y	I	C	H	F	L	L	H	L	P	F	T	G	R	E	D	E	L
Query Conservation
Alig confidence		.	.	.	.	.	.	.	.	.																						.
Template Conservation		.	.	.	.	.	.	.	.	.																						.
Template Sequence		.	.	.	.	.	.	.	.	.	K	L	I	M	E	Y	L	P	Y	G	S	L	R	D	Y	L	Q	K	H	K	E	.	R	I	D	H	I	K	L	L	Q	Y	T	S	Q	I	C	K	G	M	E	Y	L	G	T	K	R	Y	I	H	R	D	L	A	T	R	N	I	L	V	E	N	E	N	R	V	K	I	G	D	F
Template Known Secondary structure		.	.	.	.	.	.	.	.	.								T	T		B					T	T	T	S	T	T	.	T																						T	T	T								G	G	G						T	T
Template Predicted Secondary structure		.	.	.	.	.	.	.	.	.																						.
Template SS confidence
											926	.	.	.	930	.	.	.	.	.	.	.	.	.	940	.	.	.	.	.	.		.	.	.	950	.	.	.	.	.	.	.	.	.	960	.	.	.	.	.	.	.	.	.	970	.	.	.	.	.	.	.	.	.	980	.	.	.	.	.	.	.	.	.	990	.	.	.	.	.
		182	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.
Predicted Secondary structure
Query SS confidence
Query Sequence		K	I	S	V	I	D	L	H	R	A	Q	I	R	A	K	V	P	R	R	W	R	D	K	D	L	I	G	L	Y	F	S	S	M	N	I	G	L	T	Q	R	D	I	W	R	F	M	K	V	Y	F
Query Conservation
Alig confidence													.	.
Template Conservation													.	.
Template Sequence		G	L	T	K	V	L	P	Q	D	K	E	.	.	K	V	K	E	P	G	E	S	P	I	F	W	Y	A	P	E	S	L	T	E	S	K	F	S	V	A	S	D	V	W	S	F	G	V	V	L	Y
Template Known Secondary structure		T	T						T	T			.	.					S	S				G	G	G
Template Predicted Secondary structure													.	.
Template SS confidence
		996	.	.	.	1000	.	.	.	.	.	.			.	.	.	1010	.	.	.	.	.	.	.	.	.	1020	.	.	.	.	.	.	.	.	.	1030	.	.	.	.	.	.	.	.	.	1040	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions