|   |
17 | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | |
|
|
|
. | . | . | . | . | . | 90 | . | . |
Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |
|
|  |  |
| . | . | . | . |
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | P | L | L | E | I | R | N | L | T | K | S | Y | D | G | Q | H | A | V | D | D | V | S | L | T | I | Y | K | G | E | I | F | A | L | L | G | A | S | G | C | G | K | S | T | L | L | R | M | L | A | G | F | E | Q | P | S | A | G | Q | I | M | L | D | G | V | D | L | . |
. |
. |
. |
S | Q | V | P | P | Y | L | R | P |
Query Conservation |   |
  |
|   |
|   |
|   |   |
|   |   |   |
|   |   |   |   |   |
|   |   |
|
|
|   |
|   |   |
|
|
|   |   |
|
|
|   |
|
|
|
|
|
|
|
|
|   |   |
|   |
|
|   |   |
|   |   |
|   |
|   |   |   |
|   |   |   | . | . | . | . |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|   |
|   |
|   |   |
|   |   |   |
|   |   |   |   |   |
|   |   |
|
|
|   |
|   |   |
|
|   |   |   |
|
|
|   |
|
|
|
|
|
|
|
|
|   |   |
|   |
|   |   |   |   |   |   |
|   |
|   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
T | A | A | L | H | I | G | H | L | S | K | S | F | Q | N | T | P | V | L | N | D | I | S | L | S | L | D | P | G | E | I | L | F | I | I | G | A | S | G | C | G | K | T | T | L | L | R | C | L | A | G | F | E | Q | P | D | S | G | E | I | S | L | S | G | K | T | I | F | S | K | N | T | N | L | P | V | R | E | R | R |
Template Known Secondary structure |   |
. |
|
|  |  |  |  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  |  |  |  |
| T | T |
|  |  |  |  |  |  | S | T | T | S | S |  |  |  |  |  |  |  |  |  | T | S | S |
|
| S |  |  |  |  |  |  | T | T |  |  |  |  |  | T | T |  |  |
|
| G | G | G |
|
|
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |
|
|  |  |
|
|
|
|
|
|
|
|
|  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
2 | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . |
  |
  |   |
93 | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
I | N | M | M | F | Q | S | Y | A | L | F | P | H | M | T | V | E | Q | N | I | A | F | G | L | K | Q | D | K | L | P | K | A | E | I | A | S | R | V | N | E | M | L | G | L | V | H | M | Q | E | F | A | K | R | K | P | H | Q | L | S | G | G | Q | R | Q | R | V | A | L | A | R | S | L | A | K | R | P | K | L | L | L |
Query Conservation |   |
|   |   |
|   |   |   |   |   |
|   |   |   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |   |
|
|
|   |
|
|
|
|
|   |   |   |
|   |
|
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|   |
|
|
|   |
|
|
|
|
|   |   |   |
|   |
|
|
|
Template Sequence |   |
L | G | Y | L | V | Q | E | G | V | L | F | P | H | L | T | V | Y | R | N | I | A | Y | G | L | G | N | G | K | G | R | T | A | Q | E | R | Q | R | I | E | A | M | L | E | L | T | G | I | S | E | L | A | G | R | Y | P | H | E | L | S | G | G | Q | Q | Q | R | A | A | L | A | R | A | L | A | P | D | P | E | L | I | L |
Template Known Secondary structure |   |
|  |  |  |
| T | T |
|
|
|
| T | T | S |
|  |  |  |  |  |  | T | T | S | T | T | S | S |
|
| S |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
| G | G | G | T | T |
|
| G | G | G | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
| S |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
82 | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . |
  |
  |   |
173 | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . |
Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | D | E | P | M | G | A | L | D | K | K | L | R | D | R | M | Q | L | E | V | V | D | I | L | E | R | V | G | V | T | C | V | M | V | T | H | D | Q | E | E | A | M | T | M | A | G | R | I | A | I | M | N | R | G | K | F | V | Q | I | G | E | P | E | E | I | Y | E | H | P | T | T | R | Y | S | A | E | F | I | G | S |
Query Conservation |   |
|
|
|
|   |
|   |
|
|   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |   |
|   |
|
|
|   |
|
|
|
|   |   |
|   |   |   |   |
|
|
|
|   |
|
|   |   |
|   |
|
|   |   |
|   |   |   |
|
|   |   |   |
|   |   |   |   |
|
|   |   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|
|
|
|
|   |
|
|   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |   |
|   |
|
|
|   |
|
|
|   |   |   |
|   |   |   |   |   |
|   |
|   |
|
|   |   |
|   |
|   |   |   |
|   |   |   |
|
|   |   |   |
|   |   |   |   |   |
|   |   |   |
|   |
Template Sequence |   |
L | D | E | P | F | S | A | L | D | E | Q | L | R | R | Q | I | R | E | D | M | I | A | A | L | R | A | N | G | K | S | A | V | F | V | S | H | D | R | E | E | A | L | Q | Y | A | D | R | I | A | V | M | K | Q | G | R | I | L | Q | T | A | S | P | H | E | L | Y | R | Q | P | A | D | L | D | A | A | L | F | I | G | E |
Template Known Secondary structure |   |
 |  | S | T | T | T | T | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
| S |  |  |  |  |  |  | T | T |  |  |  |  |  |  |
|  |  |  |  |  |  | S |
| S | S |  |  |  |  |  |  |  | S |
|
Template Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
162 | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . |
  |
  |   |
253 | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . |
Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | N | V | F | E | G | V | L | K | E | R | Q | E | D | G | L | V | L | D | S | P | G | L | V | H | P | L | K | V | D | A | D | A | S | V | V | D | N | V | P | V | H | V | A | L | R | P | E | K | I | M | L | C | E | E | P | P | A | N | G | C | N | F | A | V | G | E | V | I | H | I | A | Y | L | G | D | L | S | V | Y |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |   |   |
|   |
|   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |
|
Template Sequence |   |
G | I | V | F | P | A | A | L | N | A | D | G | T | A | D | C | R | . |
. |
. |
. |
. |
. |
. |
. |
L | G | R | L | P | V | Q | S | G | A | P | A | G | T | R | G | T | L | L | I | R | P | E | Q | Y | S | L | H | P | H | S | A | P | A | . |
. |
A | S | I | H | A | V | V | L | K | T | T | P | K | A | R | H | T | E | I |
Template Known Secondary structure |   |
|  |  |  |  |  |  |  |
| S | S | S |  |  |  |  | T | . | . | . | . | . | . | . | . | T |  |  |  |  |
|
|
|
| S |
| T | T |
|  |  |  |  |  |  |
| G | G | G |
|
|
| S |
|
|
|
|
| S | . | . |  |  |  |  |  |  |  |  |  |  |  |  |
| S | S |
|  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |
|
|
|
|  |  |  |  |
| . | . | . | . | . | . | . | . |
|
|  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
| . | . |
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
242 | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
. | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | |
|
. | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . |
  |
  |   |
333 | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
H | V | R | L | K | S | G | Q | M | I | S | A | Q | L | Q | N | A | H | R | H | R | K | G | L | P | T | W | G | D | E | V | R | L | C | W | E | V | D | S | C | V | V |
Query Conservation |   |
  |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |
|   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |
| . |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . |
|   |   |
|   |   |
|   |
|   |   |   |   |   |   |
|   |   |
Template Sequence |   |
S | L | R | A | G | . |
Q | T | V | L | T | L | N | L | P | S | A | P | T | . |
. |
. |
. |
. |
L | S | D | G | I | S | A | V | L | H | L | D | G | P | A | L | F | F |
Template Known Secondary structure |   |
 |  |  |  | T | . | T |  |  |  |  |  |  |  | S | S |
|
|
| . | . | . | . | . |
| T | T | S | S |  |  |  |  |  |  |
| S |
|
|
|
|
|
Template Predicted Secondary structure |   |
 |  |  |  |
| . |
|  |  |  |  |  |  |  |
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|  |  |  |  |  |  |
|  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
312 | . | . | . | . | |
. | . | . | 320 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . |
  |