|   |
328 | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
. | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
K | R | V | A | I | I | G | A | G | P | A | G | L | A | C | A | D | V | L | T | R | N | G | V | G | V | T | V | Y | D | R | H | P | E | I | G | G | L | L | T | F | G | I | P | S | F | K | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
D | K | S | L | L | A | R | R | R | E | I | F | S | A | M | G | I | H | F | E | L | N |
Query Conservation |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
|
|
|   |
|   |   |
|
|
|   |
|
|   |   |   |   |
|
|   |
|   |   |
|
|
|   |   |   |
| . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|
|
|
|
|
|
|
|   |
|
|
|   |
|
|   |   |
|   |   |   |
|   |   |
|   |
|
|
|
|   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
R | D | L | T | I | I | G | G | G | P | T | G | I | F | A | A | F | Q | C | G | M | N | N | I | S | C | R | I | I | E | S | M | P | Q | L | G | G | Q | L | A | A | L | Y | P | E | K | H | I | Y | D | V | A | G | F | P | E | V | P | A | I | D | L | V | E | S | L | W | A | Q | A | E | R | Y | N | P | D | V | V | L | N |
Template Known Secondary structure |   |
 |  |  |  |  |  |
|
| S |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |  |  |
| S | S | S | S | S |
|  |  |  |  |  |  |
| T | T | S |  |  |
|
| B | T | T | B | S | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  | G | G | G |
|
|  |  |  |
| S |
Template Predicted Secondary structure |   |
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
15 | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . |
  |
  |   |
398 | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|  |  |  |
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
C | E | V | G | K | D | V | S | L | D | S | L | L | E | Q | Y | D | A | V | F | V | G | V | G | T | Y | R | S | M | K | A | G | L | P | N | E | D | A | P | G | V | Y | D | A | L | P | F | L | I | A | N | T | K | Q | V | M | G | L | E | E | L | P | E | E | P | F | I | N | T | A | G | L | N | V | V | V | L | G | G | G |
Query Conservation |   |
  |   |
|
|   |
|   |
|   |   |   |
|   |   |   |   |
|
|
|   |   |   |   |
|   |   |   |   |   |   |
|   |
|   |
|   |   |   |   |
|
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|
|
|
|
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
E | T | V | T | K | Y | T | K | L | . |
. |
D | D | G | T | F | E | T | R | T | N | T | G | N | V | Y | R | S | R | A | V | L | I | A | A | G | L | G | A | F | E | P | R | K | L | P | Q | L | G | N | I | D | H | L | T | G | S | S | V | Y | Y | A | V | K | S | V | E | D | F | K | G | K | R | V | V | I | V | G | G | G |
Template Known Secondary structure |   |
|
|  |  |  |  |  |  |
| . | . | T | T | S |
|  |  |  |  |  | T | T | S |
|  |  |  |  |  |  |  |  |  |
|
| T | T | S |  |  |  |  |
|
|
| G | G | G |
|
|
| T | T | T | B | T | T | T |  |  | S | S |
| S |
| G | G | G | G | T | T |
|  |  |  |  |  |
| S | S |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
| . | . |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
95 | . | . | . | . | 100 | . | . | . | |
|
. | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . |
  |
  |   |
478 | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
D | T | A | M | D | C | V | R | T | A | L | R | H | G | A | S | N | V | T | C | A | Y | R | R | D | E | A | N | M | P | G | S | K | K | E | V | K | N | A | R | E | E | G | A | N | F | E | F | N | V | Q | P | V | A | L | E | L | N | E | Q | G | H | V | C | G | I | R | F | L | R | T | R | L | G | E | P | D | A | Q | G |
Query Conservation |   |
  |
|
|   |
|   |
|   |   |   |   |
|   |
|
|   |   |
|
|
|
|   |
|   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |
|
|
|   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |
|   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |
|   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . |
Template Sequence |   |
D | S | A | L | D | W | T | V | G | L | I | K | N | A | A | S | V | T | L | V | H | R | G | H | E | F | Q | G | H | G | K | T | A | H | E | V | E | R | A | R | A | N | G | T | I | D | V | Y | L | E | T | E | V | A | S | I | E | E | S | N | G | V | L | T | R | V | H | L | R | S | S | . |
. |
. |
. |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  | T | T | T | T | S | S |  |  |  |  |  |  | S | S | S | S |
| S | S |
| S |  |  |  |  |  |  |  |  |  |  |  | T | T | S | S |  |  |  |  | T |
|  |  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  |
| S | . | . | . | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
| . | . | . | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
173 | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | |
|
|
|
|
|
|
|
|
  |
  |   |
558 | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | |
|
|
. | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |
|
|  |  |  |
|
|  |  |  |  |  |  |
|
|
|  |  |
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|  | . | . | . |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
Query Sequence |   |
R | R | R | P | V | P | V | E | G | S | E | F | V | M | P | A | D | A | V | I | M | A | F | G | F | N | P | H | G | M | P | W | L | E | S | H | G | V | T | V | D | K | W | G | R | I | I | A | D | V | E | S | Q | Y | R | Y | Q | T | T | N | P | K | I | F | A | G | G | D | A | V | R | G | A | D | L | . |
. |
. |
V | V |
Query Conservation |   |
  |   |   |   |   |   |   |   |
|   |   |   |   |
|   |
|
|   |
|
|   |
|
|
|   |   |
|   |   |   |   |
|   |   |   |   |
|
|   |   |   |   |   |
|   |
|   |
|   |   |   |   |   |   |   |   |   |
|
|   |
|
|
|
|
|   |
|
|
|   |   |
|   |   |   | . | . | . |
|
|
Alig confidence |   |
. | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
Template Conservation |   |
. | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |   | . |   |   |   |
|   |
|   |   | . | . | . | . |   |   |   |
|   |   |   |   |
|   |
|   |
|
|
|
|   |   |
|   |   |   |   |   |   |   |
Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
D | G | S | K | W | T | V | E | A | D | R | L | L | I | L | I | G | F | K | S | N | L | G | . |
P | L | A | R | W | D | L | E | L | Y | . |
E | N | A | L | V | V | D | S | . |
. |
. |
. |
H | M | K | T | S | V | D | G | L | Y | A | A | G | D | I | A | Y | Y | P | G | K | L | K | I | I | Q |
Template Known Secondary structure |   |
. | . | . | . | . | . | . | S | S |
|  |  |  |  |  |
| S |  |  |  |  |
| S |
|  |  |  |  |
|  | . |  |  |  | T | S | S | S |
|  |  | . | T | T |  |  |  |
|
| T | . | . | . | . | T | S | B |
| S | S | T | T |  |  |  |
| G | G | G |  |  |
| T | T |
|
|
| S |  |  |
Template Predicted Secondary structure |   |
. | . | . | . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  | . |  |  |  |  |
|
|
|
|
|
| . |
|
|  |  |  |  |
|
| . | . | . | . |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
|
244 | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | |
. | . | . | 270 | . | . | . | . | . | . | |
. | . | . | 280 | . | . | . | . | |
|
|
|
. | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 |
  |
  |   |
635 | . | . | . | . | 640 | . | . | . | . | . | . | . | . | . | 650 | . | . | |
. | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . |
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
Query Sequence |   |
T | A | M | A | E | G | R | H | A | A | Q | G | I | I | D | W | L | G | . |
V | K | S | V | K | S | H |
Query Conservation |   |
  |
|
|   |   |
|
|   |
|
|   |   |
|   |   |   |
|   | . |   |   |   |   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |   |   |
|   |   |
|
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |
Template Sequence |   |
T | G | L | S | E | A | T | M | A | V | R | H | S | L | S | Y | I | K | P | G | E | K | I | R | N | V |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S | T | T |
|
|
|
|
|
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
311 | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . |
  |