|   |
222 | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | |
|
|
|
. | 290 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
Query Sequence |   |
H | S | F | G | A | K | Y | D | F | K | N | N | F | V | L | E | A | A | F | G | Q | A | E | G | Y | I | D | Q | Y | F | A | K | A | S | Y | K | F | D | I | A | G | S | P | L | T | T | S | Y | Q | F | Y | G | T | R | D | K | V | D | D | R | S | V | N | D | L | Y | D | . |
. |
. |
. |
G | T | A | W | L | Q | A | L | T |
Query Conservation |   |
  |   |   |
|
|   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |   |
|   |   |   |
|   |   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
| . | . | . | . |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |
|   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|
Template Sequence |   |
G | R | L | G | L | T | Y | K | L | T | D | N | T | V | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
G | A | M | Y | N | F | K | T | S | V | G | D | L | E | G | K | A | T | L | S | A | I | S | G | D | G | A | V | L | P | L | D | G | D | I | R | V | K | N | F | E | M | P | A | S | L | T | L | G |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |
| S | S | S |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |
|
| B |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
| T | T | S |
|  |  |  |  |  |  |  |  |  |  |  |
|
|
| B |
|  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
|
|  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |
|
|  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
221 | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . |
  |
  |   |
298 | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|  |  |  |
|
|
|
|
|  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
F | G | Y | R | A | A | D | V | V | D | L | R | L | E | G | T | W | V | K | A | D | G | Q | Q | G | Y | F | L | Q | R | M | T | P | T | Y | A | S | S | N | G | R | L | D | I | W | W | D | N | R | S | D | F | N | A | N | G | E | K | A | V | F | F | G | A | M | Y | D | L | K | N | W | N | L | P | G | F | A | I | G | A |
Query Conservation |   |
  |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |
|   |
|   |   |   |   |   |   |
|
|
|   |   |   |
|
|
|
|
|   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . |   |
|   |   |   |   |   |   |
|   |
|
|   |   | . | . | . | . |   |   |   |   |   |
|
|
|
Template Sequence |   |
L | A | H | Q | F | N | E | R | W | V | V | A | A | D | I | K | R | A | Y | W | G | D | V | M | D | S | M | N | V | A | F | I | S | Q | L | G | G | I | D | V | A | L | P | H | R | Y | . |
. |
. |
. |
. |
. |
. |
. |
Q | D | I | T | V | A | S | I | G | T | A | Y | K | Y | . |
. |
. |
. |
N | N | D | L | T | L | R | A |
Template Known Secondary structure |   |
 |  |  |
| S | S | S | S |
|  |  |  |  |  |  |  |  |  |  |
| T | T |
|
| S |  |  |  |  |  |  |  |
| S | S |
|  |  |  |  |  |  |  |
|
|
| . | . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |
| S | . | . | . | . | S | S | S |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |
| . | . | . | . |
|
|
|  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
285 | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | |
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 340 | . | . | . | . | |
|
|
|
. | . | . | . | . | 350 | . | . |
  |
  |   |
378 | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
S | Y | V | Y | A | W | D | A | K | P | A | T | W | Q | S | N | P | D | A | Y | Y | D | K | N | R | T | I | E | E | S | A | Y | S | L | D | A | V | Y | T | I | Q | D | G | R | A | K | G | T | M | F | K | L | H | F | T | E | Y | D | N | H | S | D | I | P | S | W | G | G | G | Y | G | N | I | F | Q | D | E | R | D | V |
Query Conservation |   |
  |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |
|   |   |
|   |
|   |
|
|
|
|
|   |
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|   |
|
|   |
|
|   |   |   |   |
|   |   | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |
|   |
|   |
|   |   |   |   | . | . | . | . |   |   |   |   |
|
|
|
|   |   |
|   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . |   |   |   |   |   |   |
|   |
Template Sequence |   |
G | Y | S | Y | A | Q | L | I | L | P | V | I | P | A | Y | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
L | K | R | H | V | T | F | G | G | E | Y | D | F | D | . |
. |
. |
. |
K | D | S | R | I | N | L | A | I | S | F | G | L | R | E | R | V | M | L | R | . |
. |
. |
. |
. |
. |
. |
Q | S | H | S | Q | I | N | A |
Template Known Secondary structure |   |
 |  |  |  |  |
|
|
|
| T | T | S |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
| S |
|  |  |  |  |  |  |  |  |
| S | S | . | . | . | . | S | S |
|
|
|  |  |  |  |  |  |  |
|
|  |  |
|
|
|
| . | . | . | . | . | . | . |  |  |  |
| B |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |
|
| . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
353 | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
. | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | |
|
|
|
. | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | |
|
|
|
|
|
|
. | . | . | . | . | . | . | . |
  |
  |   |
458 | . | 460 | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
Query Sequence |   |
K | F | M | V | I | A | P | F |
Query Conservation |   |
|
|   |
|   |
|   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |
Template Sequence |   |
V | V | S | Y | S | K | N | F |
Template Known Secondary structure |   |
 |  |  |
|
|
|
|
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
  |   |
426 | . | . | . | 430 | . | . | . |
  |