Secondary structure and disorder prediction

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Sequence		M	K	H	N	P	L	V	V	C	L	L	I	I	C	I	T	I	L	T	F	T	L	L	T	R	Q	T	L	Y	E	L	R	F	R	D	G	D	K	E	V	A	A	L	M	A	C	T	S	R
Secondary structure
SS confidence
Disorder		?	?	?	?	?																																									?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 3m5b chain A Region: 25 - 42 Aligned: 18 Modelled: 18 Confidence: 18.0% Identity: 28% PDB header:transcription Chain: A: PDB Molecule:zinc finger and btb domain-containing protein 32; PDBTitle: crystal structure of the btb domain from fazf/zbtb32 Phyre2 PDB 2km6 chain A Region: 15 - 30 Aligned: 16 Modelled: 16 Confidence: 10.2% Identity: 13% PDB header:signaling protein, protein binding Chain: A: PDB Molecule:nacht, lrr and pyd domains-containing protein 7; PDBTitle: nmr structure of the nlrp7 pyrin domain Phyre2 PDB 1vlf chain N domain 1 Region: 30 - 42 Aligned: 13 Modelled: 13 Confidence: 9.9% Identity: 38% Fold: Prealbumin-like Superfamily: Cna protein B-type domain Family: Cna protein B-type domain Phyre2 PDB 2qqr chain A domain 1 Region: 23 - 37 Aligned: 15 Modelled: 15 Confidence: 7.9% Identity: 53% Fold: SH3-like barrel Superfamily: Tudor/PWWP/MBT Family: Tudor domain Phyre2 PDB 2vty chain A Region: 16 - 25 Aligned: 10 Modelled: 10 Confidence: 6.5% Identity: 60% PDB header:apoptosis Chain: A: PDB Molecule:protein f1; PDBTitle: vaccinia virus anti-apoptotic f1l is a novel bcl-2-like2 domain swapped dimer Phyre2 PDB 1khi chain A domain 2 Region: 25 - 45 Aligned: 21 Modelled: 21 Confidence: 5.7% Identity: 29% Fold: OB-fold Superfamily: Nucleic acid-binding proteins Family: Cold shock DNA-binding domain-like Phyre2 PDB 3qii chain A Region: 23 - 41 Aligned: 19 Modelled: 19 Confidence: 5.5% Identity: 21% PDB header:transcription regulator Chain: A: PDB Molecule:phd finger protein 20; PDBTitle: crystal structure of tudor domain 2 of human phd finger protein 20 Phyre2 PDB 3arc chain L Region: 5 - 21 Aligned: 17 Modelled: 17 Confidence: 5.5% Identity: 35% PDB header:electron transport, photosynthesis Chain: L: PDB Molecule:photosystem ii reaction center protein l; PDBTitle: crystal structure of oxygen-evolving photosystem ii at 1.9 angstrom2 resolution Phyre2 PDB 1pn5 chain A domain 1 Region: 15 - 30 Aligned: 16 Modelled: 16 Confidence: 5.4% Identity: 13% Fold: DEATH domain Superfamily: DEATH domain Family: Pyrin domain, PYD Phyre2 PDB 1pn5 chain A Region: 15 - 30 Aligned: 16 Modelled: 16 Confidence: 5.4% Identity: 13% PDB header:apoptosis Chain: A: PDB Molecule:nacht-, lrr- and pyd-containing protein 2; PDBTitle: nmr structure of the nalp1 pyrin domain (pyd) Phyre2 PDB 2zxe chain B Region: 5 - 22 Aligned: 18 Modelled: 18 Confidence: 5.1% Identity: 28% PDB header:hydrolase/transport protein Chain: B: PDB Molecule:na+,k+-atpase beta subunit; PDBTitle: crystal structure of the sodium - potassium pump in the e2.2k+.pi2 state Phyre2 1 c3m5bA_ 2 c2km6A_ 3 d1vlfn1 4 d2qqra1 5 c2vtyA_ 6 d1khia2 7 c3qiiA_ 8 c3arcl_ 9 d1pn5a1 10 c1pn5A_ 11 c2zxeB_

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c3m5bA_ 18.0 28 PDB header:transcription Chain: A: PDB Molecule:zinc finger and btb domain-containing protein 32; PDBTitle: crystal structure of the btb domain from fazf/zbtb32 2 c2km6A_ 10.2 13 PDB header:signaling protein, protein binding Chain: A: PDB Molecule:nacht, lrr and pyd domains-containing protein 7; PDBTitle: nmr structure of the nlrp7 pyrin domain 3 d1vlfn1 9.9 38 Fold:Prealbumin-like Superfamily:Cna protein B-type domain Family:Cna protein B-type domain 4 d2qqra1 7.9 53 Fold:SH3-like barrel Superfamily:Tudor/PWWP/MBT Family:Tudor domain 5 c2vtyA_ 6.5 60 PDB header:apoptosis Chain: A: PDB Molecule:protein f1; PDBTitle: vaccinia virus anti-apoptotic f1l is a novel bcl-2-like2 domain swapped dimer 6 d1khia2 5.7 29 Fold:OB-fold Superfamily:Nucleic acid-binding proteins Family:Cold shock DNA-binding domain-like 7 c3qiiA_ 5.5 21 PDB header:transcription regulator Chain: A: PDB Molecule:phd finger protein 20; PDBTitle: crystal structure of tudor domain 2 of human phd finger protein 20 8 c3arcl_ 5.5 35 PDB header:electron transport, photosynthesis Chain: L: PDB Molecule:photosystem ii reaction center protein l; PDBTitle: crystal structure of oxygen-evolving photosystem ii at 1.9 angstrom2 resolution 9 d1pn5a1 5.4 13 Fold:DEATH domain Superfamily:DEATH domain Family:Pyrin domain, PYD 10 c1pn5A_ 5.4 13 PDB header:apoptosis Chain: A: PDB Molecule:nacht-, lrr- and pyd-containing protein 2; PDBTitle: nmr structure of the nalp1 pyrin domain (pyd) 11 c2zxeB_ 5.1 28 PDB header:hydrolase/transport protein Chain: B: PDB Molecule:na+,k+-atpase beta subunit; PDBTitle: crystal structure of the sodium - potassium pump in the e2.2k+.pi2 state

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0