|   |
78 | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | |
|
|
|
|
. | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | |
|
|
. | 140 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  | . | . | . | . | . |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Q | L | D | S | V | V | R | I | A | S | L | T | K | L | M | T | S | E | M | L | V | K | L | L | D | Q | G | T | V | K | L | N | D | P | L | . |
. |
. |
. |
. |
S | K | Y | A | P | P | G | A | R | V | P | T | Y | N | G | T | P | I | T | L | V | N | L | A | T | H | . |
. |
. |
T | S | A | L | P | R | E | Q | P | G | G |
Query Conservation |   |
  |   |   |
|   |
|   |
|
|
|
|
|
|   |   |
|
|   |   |
|   |   |
|
|
|   |
|
|
|   |
|
|
|   |
| . | . | . | . | . |   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |
|
|
|
| . | . | . |
|
|
|
|   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
| . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |
|   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |   |   |   |
|   |   |
| . | . | . | . | . | . | . | . | . |
Template Sequence |   |
A | P | E | R | P | M | P | T | G | A | A | Y | K | L | Y | L | M | R | A | L | V | A | E | I | E | K | G | T | V | G | W | D | E | I | L | T | L | T | P | E | L | R | S | L | P | T | G | D | M | Q | D | L | P | D | G | T | R | V | T | V | R | E | T | A | H | K | M | I | A | L | S | . |
. |
. |
. |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
S | T | T | S |
|  |  |
| G | G | G |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | S | S |
| T | T |
|  |  |  |
|
| G | G | G |
|
|
| S | S | S | S | G | G | G | S |
| T | T |
|  |  |  |  |  |  |  |  |  |  |  |  |  | T |
| . | . | . | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . | . | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
164 | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | |
|
|
|
|
|
|
|
|
  |
  |   |
150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | |
|
|
|
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
Query Sequence |   |
A | A | H | R | P | V | F | V | W | P | T | R | E | Q | R | W | K | Y | L | S | T | A | K | L | K | A | A | P | G | S | Q | A | A | Y | S | N | L | A | F | D | L | L | A | D | A | L | A | N | A | S | G | K | P | Y | T | Q | L | F | E | E | Q | I | T | R | P | L | G | M | K | D | T | T | Y | T | P | S | . |
. |
. |
. |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |
|
|
|   |   |
|   |
|
|   |   |
|
|
|   |
|
|
|   |   |   |   |   |   |
|   |   |   |
|   |   |
|
|
|
|   |   |
|   |   |   |   |   | . | . | . | . |
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
Template Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |
|   |
|   |   |   |
|   |   |   |   |
|   | . | . | . | . | . | . | . |   |   |   |   |   | . |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |
Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
D | N | T | G | A | D | L | V | A | D | R | L | G | R | . |
. |
. |
. |
. |
. |
. |
E | V | V | E | R | . |
S | L | A | A | A | G | H | H | D | P | S | L | M | R | P | F | L | T | S |
Template Known Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . |  |  |  |  |  | . |  |  |  |  |  | T |
| S |
| G | G | G | G |
| S |
|
|
|  |
Template Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . |  |  |  |  |  | . |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
235 | . | . | . | . | 240 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
. | 250 | . | . | . | |
. | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . |
  |
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
226 | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 |
Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |
|
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
P | D | Q | C | R | R | L | M | V | A | E | R | G | A | S | P | C | N | N | T | L | A | A | I | G | S | G | G | V | Y | S | T | P | G | D | M | M | R | W | M | Q | Q | Y | L | S | S | D | F | Y | Q | R | S | N | Q | A |
Query Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |
|
|   |   |
|
|
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
H | E | V | F | E | L | G | W | G | D | P | E | R | R | A | E | W | V | R | Q | D | E | A | G | R | R | E | L | L | E | K | M | A | G | V | M | T | V | R | G | S | D | L | G | A | T | V | H | Q | L | G | I | D | W | H | M | D | A | F | D | V | V | R | V | L | E | G | L | L | Q | D | S | G | R | D | T | S | G | T | V |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  | S |
|  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |
| S | S |
|
|
|
| G | G | G |
|
| S |
|
| G | G | G | T |
| S |
|  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| T | T | S |  |  |
Template Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
273 | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . |
  |
  |   |
281 | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | |
|
. | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  | . | . |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
D | R | M | Q | T | L | I | Y | Q | R | A | Q | F | T | K | V | I | G | M | D | V | P | G | K | A | D | A | L | G | L | G | W | V | Y | M | A | P | K | E | G | R | P | G | I | I | Q | K | T | G | G | G | G | G | F | I | T | Y | M | A | M | . |
. |
I | P | Q | K | N | I | G | A | F | V | V | V | T | R | S | P | L | T |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |
|   |   |
|   |   |   |   | . | . |   |
|
|   |   |   |   |
|
|
|
|   |
|   |   |   |   |   |
Alig confidence |   |
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|
|
|   |   |   |   |   |   |   |
Template Sequence |   |
E | E | I | L | T | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
A | Y | P | G | L | L | I | D | E | E | R | W | R | R | V | Y | F | K | A | G | S | S | P | G | V | M | M | F | C | W | L | L | Q | D | H | A | G | I | S | Y | V | L | V | L | R | Q | S | A | D | E | Q |
Template Known Secondary structure |   |
 |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | S |
|
| S | S |
|
|
| T | T | T |  |  |  |  |  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  |  |  | T | T | S |
|  |  |  |  |  |  |  |  |  |  | S | S | G |
Template Predicted Secondary structure |   |
 |  |  |  |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
353 | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . |
  |
  |   |
359 | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | F | K | N | M | S | D | G | I | N | D | L | V | T | E | L |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|
Template Sequence |   |
R | L | I | G | D | G | L | F | L | R | G | I | G | A | K | I |
Template Known Secondary structure |   |
G | G | T | T | T | S |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
409 | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . |
  |