|   |
430 | . | . | . | . | . | |
. | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|  | . |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
K | S | G | E | R | I | . |
K | V | M | L | N | A | G | L | S | P | E | H | E | E | K | L | G | S | R | I | D | G | I | G | L | Y | R | T | E | I | P | F | M | L | Q | S | G | F | P | S | E | E | E | Q | V | A | Q | Y | Q | G | M | L | Q | M | F | N | D | K | P | V | T | L | R | T | L | D | V | G | A | D | K | Q | L |
Query Conservation |   |
  |
|
|   |   |   | . |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|
|
|   |
|
|
|   |   |   |   |   |   |   |   |   |
|   |
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|
|
|   |
|   |
|
|   |   |
Alig confidence |   |
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
Template Conservation |   |
  |   |
|   |   |   |   |
|   |   |   |   |   |   |
|
|   |   |   |
|   |   |
|   |   |
|   |
|   |
| . | . | . | . | . | . | . | . |   |
|
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   | . |   |
|   |   |   |   |
|
|
|   |   |   |   |   |   | . | . | . |
Template Sequence |   |
A | A | K | Q | V | Q | I | G | C | W | S | A | L | S | N | P | I | S | T | E | V | L | G | L | A | G | F | D | W | L | . |
. |
. |
. |
. |
. |
. |
. |
V | L | D | G | E | H | A | P | N | D | I | S | T | F | I | P | Q | L | M | A | L | K | G | . |
S | A | S | A | P | V | V | R | V | P | T | N | E | P | V | . |
. |
. |
Template Known Secondary structure |   |
 | T | T |
|
|  |  |  |  |  |  |
| S |
| S |  |  |  |  |  |  |  | T | T | S |
|
| S |  |  | . | . | . | . | . | . | . | . |  |  |  | S | S | S | S | S |
|
|  |  |  |  |  |  |  |  |  |  | T | T | T | . |
| S | S |  |  |  |  |  |
| S | S | S |
|  |  | . | . | . |
Template Predicted Secondary structure |   |
 |
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  | . | . | . | . | . | . | . | . |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | . |
|
|
|
|  |  |  |  |
|
|
|
|
|  |  | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
15 | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | |
|
|
|
|
|
|
|
. | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | |
. | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | |
|
|
  |
  |   |
509 | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Sequence |   |
P | Y | M | P | I | S | E | E | N | P | C | L | G | W | R | G | I | R | I | T | L | D | Q | P | E | I | F | L | I | Q | V | R | A | M | L | R | A | N | A | A | T | G | N | L | N | I | L | L | P | M | V | T | S | L | D | E | V | D | E | A | R | R | L | I | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Conservation |   |
  |   |   |   |   |   |
|   |
|
|   |
|
|   |
|
|
|
|   |   |
|   |   |   |   |   |   |   |   |
|
|
|
|   |
|
|
|   |
|   |   |   |   |   |   |
|
|   |
|
|
|   |   |   |   |
|   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
| . |
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |
|   |   |   |
|
|   |
|
| . |   |
| . | . | . |
|
|
|
|   |
|   |   |   |
|   |
|   |   |   |   |   |   |   |   |
|   |
|   |
|   |
|   |   |   |   |   |   |   |   |
Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
I | I | K | R | L | L | D | I | G | F | . |
Y | N | . |
. |
. |
F | L | I | P | F | V | E | T | K | E | E | A | E | L | A | V | A | S | T | R | Y | P | P | E | G | I | R | G | V | S | V | S | H | R | A |
Template Known Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  | T | T |
| . |
|  | . | . | . |  |  |  | S |
|
|
| S |  |  |  |  |  |  |  |  |  | T | T | S |
| T | T | T |
|
|
|
|
|
| S | S | S | G | G |
Template Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |
|
|
| . |
|  | . | . | . |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
83 | . | . | . | . | . | . | 90 | . | . | |
. | . | |
|
|
. | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . |
  |
  |   |
|
|
|
|
|
|
573 | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . | . | . | . | 610 | |
|
. | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | . | . | . | . | . | . | . | 640 | . | . | . | . |
Predicted Secondary structure |   |
. | . | . | . | . | . |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  | . | . |  |  |
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
. |
E | R | A | G | R | E | V | E | E | M | I | G | Y | E | I | P | K | P | R | I | G | I | M | L | E | V | P | S | M | V | F | M | L | P | H | L | A | K | . |
. |
R | V | D | F | I | S | V | G | T | N | D | L | T | Q | Y | I | L | A | V | D | R | N | N | T | R | V | A | N | I | Y | D | S | L | H |
Query Conservation |   |
. | . | . | . | . | . |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|   |
|   |
|   |   |   |   |   |   |   |   |   | . | . |   |   |
|
|   |
|
|
|
|
|
|
|   |
|
|   |   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
. | . | . | . | . | . |
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . |   |   |   |   |   |
|
|   |   |
|
|
|   |   |
|
|   |
|
|   |
|
|   |
|   |
|
|
|
|   |
|   |
|
|   |   |
|
|
|   |
|
| . | . | . | . | . | . | . | . | . | . |
|   |   |   |   |   |   |   |
Template Sequence |   |
N | M | F | G | T | V | A | D | Y | F | A | Q | S | . |
. |
. |
. |
. |
. |
. |
N | K | N | I | T | I | L | V | Q | I | E | S | Q | Q | G | V | D | N | V | D | A | I | A | A | T | E | G | V | D | G | I | F | V | G | P | S | D | L | A | A | A | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
G | H | L | G | N | A | S | H |
Template Known Secondary structure |   |
G | G | G | G | T | S | T | T |  |  |  |  |  | . | . | . | . | . | . | . | T | T | S |
|  |  |  |  |  |  |
| S |  |  |  |  |  | T |  |  |  |  |  | T | S | T | T |
|
|  |  |  |  |
|  |  |  |  |  |  |  | T | . | . | . | . | . | . | . | . | . | . | T |
| T | T |
| T | T | S |
Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |
| . | . | . | . | . | . | . |
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
130 | . | . | . | . | . | . | . | . | . | 140 | . | . | |
|
|
|
|
|
|
. | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | |
|
|
|
|
|
|
|
|
|
. | . | . | . | . | 190 | . | . |
  |
  |   |
645 | . | . | . | . | 650 | . | . | . | . | . | . | . | . | . | 660 | . | . | . | . | . | . | . | . | . | 670 | . | . | . | . | . | . | . | . | . | 680 | . | . | . | . | . | . | . | . | . | 690 | . | . | . | . | . | . | . | . | . | 700 | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
P | A | M | L | R | A | L | A | M | I | A | R | E | A | E | I | H | G | I | D | L | R | L | C | G | E | M | A | G | D | P | M | C | V | A | I | L | I | G | L | G | Y | R | H | L | S | M | N | G | R | S | V | A | R | A | K | Y | L | L | R | R | I |
Query Conservation |   |
|
|
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|
|   |
|   |   |
|   |   |   |   |   |
|   |
|
|
|   |   |   |
|
|   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |   |   |
|   |   |   |
|   |   |
|
|   |   |   |
|   |   | . | . | . |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   | . |
|   |   |   |
|   |   |   |   |   |   |   |
Template Sequence |   |
P | D | V | Q | K | A | I | Q | H | I | F | N | R | A | S | A | H | G | K | P | . |
. |
. |
S | G | I | L | A | P | V | E | A | D | A | R | R | Y | L | E | W | G | A | T | F | V | A | V | G | S | . |
D | L | G | V | F | R | S | A | T | Q | K | L |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
| . | . | . |  |  |  |  |
|
| S |  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |  |  |  |  | . |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  | . | . | . |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|  | . |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
193 | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | |
|
|
. | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | |
. | 240 | . | . | . | . | . | . | . | . | . | 250 |
  |