|   |
10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | |
. | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
. | 70 | . | . | . | . | . | . | . | . | |
. | 80 |
Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
| . |
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| . | . | . | . | . | . | . |
|
|
|
|  |  |  |  |  |
| . |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
| . |
|
|
Query Sequence |   |
F | E | S | C | G | T | V | D | G | P | G | I | R | F | I | T | F | F | Q | . |
G | C | L | M | R | C | L | Y | C | H | N | R | D | T | W | D | T | H | G | G | K | E | V | T | V | E | D | L | M | K | E | V | V | T | Y | R | H | F | M | N | . |
. |
. |
. |
. |
. |
. |
A | S | G | G | G | V | T | A | S | G | . |
G | E |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|
|   |   | . |
|
|
|   |   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|   |   |   |
|   |   |   |   |   |   |   |   | . | . | . | . | . | . | . |   |   |   |   |   |
|   |   |   |
| . |
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
| . |
|
|
Template Conservation |   |
|
|   |
|   |
|   |   |   |   |
|   |
|   |
|
|
|
|
|
|
|
|   |   |   |
|   |
|
|   | . | . | . |
|   |   |   |
|   |   |
|   |
|
|   |   |
|
|
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |
|   |
|
|
Template Sequence |   |
V | E | T | V | Y | I | P | E | D | D | R | A | T | L | C | V | S | S | Q | V | G | C | A | L | E | C | K | F | C | S | . |
. |
. |
T | A | Q | Q | G | F | N | R | N | L | R | V | S | E | I | I | G | Q | V | W | R | A | A | K | I | V | G | A | A | K | V | T | G | Q | R | P | I | T | N | V | V | M | M | G | M | G | E |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |
| S | S |
|  |  |  |  |
|
|
|  |  |  |
| S | S |
|
| T | T |
| G | . | . | . | G | G | T | T |
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  | S | S |
| S |
| S |  |  |  |  |
| S | S | S |
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  | . | . | . |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
104 | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | |
|
|
. | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 |
  |
  |   |
81 | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | |
|
|
. | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
. | . | . |
Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . |
|
|
|
|
|  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
| . | . | . | . | . | . | . | . |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
|
|
|
Query Sequence |   |
A | I | L | Q | A | E | F | V | R | D | W | F | R | A | C | K | K | E | . |
. |
. |
G | I | H | T | C | L | D | T | N | G | F | V | R | R | Y | D | P | V | I | D | E | L | L | E | V | T | D | L | V | M | L | D | L | K | Q | M | N | D | E | I | H | Q | N | L | V | G | V | S | . |
. |
. |
. |
. |
. |
. |
. |
N | H | R |
Query Conservation |   |
|
|
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   | . | . | . |   |   |   |   |   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
Template Conservation |   |
|
|   |
|   |   |   |
|   |   |   |
|   |   |
|   |   |   |   |
|
|   |
|   |   |   |   |
|
|
|
|
|   |
|   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |
|   |
|
|
|   |
|   |   |   |
|   |
|   |   |
|   |
|   |   |
|   |   |   |
|   |   |
|   |   |   |
Template Sequence |   |
P | L | L | N | L | N | N | V | V | P | A | M | E | I | M | L | D | D | F | G | F | G | L | S | K | R | R | V | T | L | S | T | S | G | V | V | P | A | L | D | K | L | G | D | M | I | D | V | A | L | A | I | S | L | H | A | P | N | D | E | I | R | D | E | I | V | P | I | N | K | K | Y | N | I | E | T | F | L | A | A |
Template Known Secondary structure |   |
G | G | G |
|  |  |  |  |  |  |  |  |  |  |  |  | S | T | T | T | T |
|
|
| G | G | G |  |  |  |  |  | S |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
| S | S |  |  |  |  |  |  |  | S | G | G | G | G | T | S |
|  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
181 | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 |
  |
  |   |
150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | L | E | F | A | K | Y | L | A | N | K | N | V | K | V | W | I | R | Y | V | V | V | P | G | W | S | D | D | D | D | S | A | H | R | L | G | E | F | T | R | D | M | G | N | V | E | K | I | E | L | L | P | Y | H | E | L | G | K | H | K | W | V | A | M | G | E | E | Y | K | L | D | G | V | K | P | P | K | K | E | T |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |
|   |
|   |
|
|   |
|   |
|
|
|   |
|   |
|   |   |
|   |   |   |
|   |   |   |   | . | . |   |   |
|
|
|
|
|   |
|
|   |   |
|   |   | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |
|   |   |
|   |
Template Sequence |   |
V | R | R | Y | L | E | K | S | N | A | N | Q | G | R | V | T | I | E | Y | V | M | L | D | H | V | N | D | G | T | E | H | A | H | Q | L | A | E | L | L | K | D | T | P | . |
. |
C | K | I | N | L | I | P | W | N | P | F | P | G | A | P | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Y | G | R | S | S | N | S | R |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |
| T | T | T | T | T |
|  |  |  |  |  |  |  | B | T | T | T | T |
| S |  |  |  |  |  |  |  |  |  |  | T | T | T | S |
| . | . |  |  |  |  |  |  |  |
|
|
|
| T | T |
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|
| B |
|
|  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| . | . |
|  |  |  |  |  |  |
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
261 | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | |
|
. | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
. | 320 | . | . | . | . | . | . |
  |
  |   |
230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
M | E | R | V | K | G | I | L | E | Q | Y | G | H | K | V |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |
|   |   |   |
|   |   |   |
|
|   |
|
Template Sequence |   |
I | D | R | F | S | K | V | L | M | S | Y | G | F | T | T |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  | T | T |
|  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
327 | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . |
  |