|   |
1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | |
|
|
|
. | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | |
|
|
|
. | 70 | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  | . | . | . | . |
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  | . | . | . | . |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
Query Sequence |   |
M | K | I | L | V | I | G | P | S | W | V | G | D | M | M | M | S | Q | S | L | Y | R | T | L | Q | A | R | Y | P | Q | A | I | I | D | V | M | A | . |
. |
. |
. |
P | A | W | C | R | P | L | L | S | R | M | P | E | V | N | E | A | I | P | M | P | L | G | H | G | A | L | E | I | G | E | . |
. |
. |
. |
R | R | K | L |
Query Conservation |   |
|
|
|
|
|
|   |   |   |   |
|
|
|   |
|   |   |   |
|   |
|   |   |
|
|   |   |   |
|   |   |   |
|   |   |
|   | . | . | . | . |   |   |   |   |   |   |
|   |   |   |   |
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
Template Conservation |   |
  |
|
|
|   |
|   |
|
|   | . |
|   |   |   |   |   |
|   |
|   |   |   |
|   |   | . |   |   |   |   |
|
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
Template Sequence |   |
X | K | V | L | T | V | F | G | T | R | . |
P | E | A | I | K | X | A | P | L | V | H | A | L | A | K | . |
D | P | F | F | E | A | K | V | C | V | T | A | Q | H | R | E | X | L | D | Q | V | L | K | L | F | S | I | V | P | D | Y | D | L | N | I | X | Q | P | G | Q | G | L | T | E | I | T | C | R | I | L | E | G | L |
Template Known Secondary structure |   |
|  |  |  |  |  |  |
| S |  | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . |
| T | T |
|  |  |  |  |  |  |
|
| T | T | G | G | G | G |  |  |  |  |  |  | T | T |
|
|
| S |  |  |
|
|
|
| S | S | S | S |
|  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |
|
|
| . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  | . |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1 | . | . | . | . | . | . | . | . | 10 | |
. | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | |
. | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . |
  |
  |   |
73 | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | |
|
|
90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | |
|
|
|
|
|
|
|
. | . | . | . | . | . | . | 140 | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
| . | . | . |
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | H | S | L | R | E | K | R | Y | D | R | A | Y | V | L | P | N | . |
. |
. |
S | F | K | S | A | L | V | P | F | F | A | G | I | P | H | R | T | G | W | R | G | E | M | R | Y | G | L | L | N | D | V | R | V | L | D | K | E | A | W | P | L | M | V | . |
. |
. |
. |
. |
. |
. |
. |
E | R | Y | I | A | L | A | Y | D |
Query Conservation |   |
  |   |   |
|   |   |   |   |   |
|   |
|
|   |   |   |   | . | . | . |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |
|   |   |   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |
Template Sequence |   |
K | P | I | L | A | E | F | K | P | D | V | V | L | V | H | G | D | T | T | T | T | L | A | T | S | L | A | A | F | Y | Q | R | I | P | V | G | H | V | E | A | G | L | R | T | G | D | L | Y | S | P | W | P | E | E | A | N | R | T | L | T | G | H | L | A | X | Y | H | F | S | P | T | E | T | S | R | Q | N | L | L | R |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |
|
| S |  |  |  |  |  | T | T |
|  |  |  |  |  |  |  |  |  |  |  | T | T | T |
|
|  |  |  |  | S |
|
|
|
|
| S |
| T | T | S | S | T | T |  |  |  |  |  |  |  |  |  |  | T |
| S |  |  |  |  | S | S |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
79 | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . |
  |
  |   |
142 | . | . | . | . | . | . | . | 150 | . | . | . | . | . | |
|
|
|
|
|
|
|
. | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
K | G | I | M | R | T | A | Q | D | L | P | Q | P | L | . |
. |
. |
. |
. |
. |
. |
. |
L | W | P | Q | L | Q | V | S | E | G | E | K | S | Y | T | C | N | Q | F | S | L | S | S | E | R | P | M | I | G | F | C | P | G | A | E | F | G | P | A | K | R | W | P | H | Y | H | Y | A | E | L | A | K | Q | L | I | D | E | G |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |   |   |
|   |   |   |
|   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
| . | . |
|   |   |   |
|
|   |
|   |   |   |   |   |   |   |   |
Template Sequence |   |
E | N | V | A | D | S | R | I | F | I | T | G | N | T | V | I | D | A | L | L | W | V | R | D | Q | V | X | S | S | D | K | L | R | S | E | L | A | A | N | Y | P | F | I | D | P | D | K | K | X | I | L | V | T | G | H | R | R | E | S | F | G | R | . |
. |
G | F | E | E | I | C | H | A | L | A | D | I | A | T | T | H |
Template Known Secondary structure |   |
T | T |
|
| G | G | G |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  | T | T | T |
|  |  |  |  |  |  |  |  | T | T |
| T | T |
|
| T | T | S |  |  |  |  |  |
|
|
|
| B | S | S |
|
|  | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |
| . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
159 | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | |
|
. | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . |
  |
  |   |
214 | . | . | . | . | . | |
220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . |
Predicted Secondary structure |   |
|
|  |  |  |  | . |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|  |
Query SS confidence |   |
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Y | Q | V | V | L | F | . |
G | S | A | K | D | H | E | A | G | N | E | I | L | A | A | L | N | T | E | Q | Q | A | W | C | R | N | L | A | G | E | T | Q | L | D | Q | A | V | I | L | I | A | A | C | K | A | I | V | T | N | D | S | G | L | M | H | V | A | A | A | L | N | R | P | L | V | A | L | Y | G | P | S | S | P |
Query Conservation |   |
  |   |
|
|   |   | . |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |
|   |
|   |   |   |
|
|   |   |   |
|
|   |
|   |   |
|
|
|   |   |
|
|
|
|
|   |
|   |
|   |
|   |
|
|
|   |   |   |   |
Alig confidence |   |
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|
|   |   |   |   |
|
|   |   |   |
|
|
|   |
|   |
|   |
|
|
|   |   |   |   |   |
|   |   |
Template Sequence |   |
Q | D | I | Q | I | V | Y | P | V | H | L | N | P | N | V | R | E | P | V | N | R | I | L | G | H | . |
. |
. |
V | K | N | V | I | L | I | D | P | Q | E | Y | L | P | F | V | W | L | X | N | H | A | W | L | I | L | T | D | S | G | G | I | Q | E | E | A | P | S | L | G | K | P | V | L | V | X | R | D | T | T | E | R |
Template Known Secondary structure |   |
T | T |  |  |  |  |  |  |
|
| B |
|  |  |  |  |  |  |  |  |  |  |  | T | T | . | . | . |
| T | T |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
| S |  |  |  |  | S | S | S | G | G | G | G | T | G | G | G | G | T |
|
|  |  |  |
| S | S |
|
| S |
|
Template Predicted Secondary structure |   |
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
| . | . | . |
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|
|
|
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
237 | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | |
|
|
. | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . |
  |
  |   |
293 | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
D | F | T | P | P | L | S | H | K | A | R | V | I | R | L | I | T | G | Y | H | K | V | R | K | G | D | A | A | E | G | Y | H | Q | S | L | I | D | I | T | P | Q | R | V | L | E | E | L | N | A | L | L | L | Q | E | E |
Query Conservation |   |
  |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |
|   |   |   |
|   |   |
|
|   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |   |   |   |   |
|   |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |
|   |   |   |
|
|   |
|
|   |   |
|
|   |
|   |   |
Template Sequence |   |
P | E | A | V | T | A | G | T | V | R | L | V | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
G | T | D | K | Q | R | I | V | E | E | V | T | R | L | L | K | D | E | N |
Template Known Secondary structure |   |
 |  |  |  |  |  | T | S |  |  |  |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| S | S |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  |  |
Template Predicted Secondary structure |   |
 |  |  |
|
|
|
|  |  |  |  |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
314 | . | . | . | . | . | 320 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . |
  |