|   |
2 | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
60 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
K | I | L | V | I | G | P | S | W | V | G | D | M | M | M | S | Q | S | L | Y | R | T | L | Q | A | R | Y | P | Q | A | I | I | D | V | M | A | P | A | W | C | R | P | L | L | S | R | M | P | E | V | N | E | A | I | P | M | P | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
G | H | G | A | L | E | I | G | E | R |
Query Conservation |   |
|
|
|
|
|   |   |   |   |
|
|
|   |
|   |   |   |
|   |
|   |   |
|
|   |   |   |
|   |   |   |
|   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |
|   |
|   |   |
|   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|
|
|   |   |   |
|
|
|
|
|
|   |   |   |
|   |
|
|   |   |
|   |   |   | . | . |
|
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
R | L | M | V | M | A | G | G | T | G | G | H | V | F | P | G | L | A | V | A | H | H | L | M | A | Q | . |
. |
G | W | Q | V | R | W | L | G | T | A | D | R | M | E | A | D | L | V | P | K | H | G | I | E | I | D | F | I | R | I | S | G | L | R | G | K | G | I | K | A | L | I | A | A | P | L | R | I | F | N | A | W |
Template Known Secondary structure |   |
 |  |  |  |  |
|
| S | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | . | . | T |
|  |  |  |  |  |  |
| T | T | S | T |  |  |  |  | G | G | G | G | T |
|  |  |  |  |
|
|
|
|
|
| T | T |
|
|  |  |  |  |  | T |
|  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
| . | . |
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
8 | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | |
|
. | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . |
  |
  |   |
70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | |
|
. | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|  | . | . |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | K | L | G | H | S | L | R | E | K | R | Y | D | R | A | Y | V | L | P | N | S | F | K | . |
. |
S | A | L | V | P | F | F | A | G | I | P | H | R | T | G | W | R | G | E | M | R | Y | G | L | L | N | D | V | R | V | L | D | K | E | A | W | P | L | M | V | E | R | Y | I | A | L | A | Y | D | K | G | I | M | R | T |
Query Conservation |   |
  |   |   |   |   |   |
|   |   |   |   |   |
|   |
|
|   |   |   |   |   |   |   | . | . |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
Template Conservation |   |
  |   |   |   |   |   |
|   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |
Template Sequence |   |
R | Q | A | R | A | I | M | K | A | Y | K | P | D | V | V | L | G | M | G | G | Y | V | S | G | P | G | G | L | A | A | W | S | L | G | I | P | V | V | L | H | E | Q | N | G | I | A | G | L | T | N | K | W | L | A | K | I | A | T | K | V | M | Q | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
A | F | P |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
| S |  |  |  |  |
| S | S | T | T |  |  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |  |  |  |
| S | S | S |
|
|  |  |  |  |  |  | T | T | T |
| S |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | S | S | T |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
86 | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | 150 |
  |
  |   |
148 | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | Q | D | L | P | Q | P | L | L | W | P | Q | L | Q | V | S | E | G | E | K | S | Y | T | C | N | Q | F | S | L | S | S | E | R | P | M | I | G | F | C | P | G | A | E | F | G | P | A | K | R | W | P | H | Y | H | Y | A | E | L | A | K | Q | L | I | D | E | G | Y | Q | V | V | L | F | G | S | A | K | D | H | E | A |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |
|
|   |   |   |   |   |   |
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
Template Sequence |   |
G | A | F | P | N | A | E | V | V | G | N | P | V | R | T | D | V | L | A | L | P | L | P | Q | Q | R | L | A | G | R | E | G | P | V | R | V | L | V | V | G | G | S | Q | G | A | R | I | . |
. |
. |
. |
L | N | Q | T | M | P | Q | V | A | A | K | L | G | D | S | V | T | I | W | H | Q | S | G | K | G | S | Q | Q | S |
Template Known Secondary structure |   |
T | S | S | S | S |
|  |  |
|
|
|
|
|
|  |  |  |  | T | S |
|
|  |  |  |  |  | T | T |
|
| S | S |  |  |  |  |  |  |
| T | T | T |
|
|  |  | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  | G | G | G |  |  |  |  |  |  |
|
| T | T |
|  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
| . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
151 | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | |
|
|
|
. | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . |
  |
  |   |
228 | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | |
. | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | |
|
|
|
|
|
. | . | . | . | . | . | 300 |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |
|
|
|  |  |  |  |  | . |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|  |  | . | . | . | . | . | . |  |
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
Query Sequence |   |
G | N | E | I | L | A | A | L | N | T | E | Q | Q | A | W | C | R | N | L | A | G | E | T | Q | L | D | Q | A | V | I | L | I | A | A | C | K | A | I | V | T | N | D | S | G | L | M | H | V | . |
A | A | A | L | N | R | P | L | V | A | L | Y | G | P | S | S | P | D | . |
. |
. |
. |
. |
. |
F | T | P | P | L | S | H |
Query Conservation |   |
  |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |
|   |
|   |   |   |
|
|   |   |   |
|
|   |
|   |   |
|
|
|   |   |
|
| . |
|
|
|   |
|   |
|   |
|   |
|
|
|   |   |   |   |   | . | . | . | . | . | . |   |   |   |
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|
Template Sequence |   |
V | E | Q | A | Y | A | E | A | G | Q | P | Q | H | K | V | T | E | . |
. |
. |
. |
. |
. |
F | I | D | D | M | A | A | A | Y | A | W | A | D | V | V | V | C | R | S | G | A | L | T | V | S | E | I | A | A | A | G | L | P | A | L | F | V | P | F | Q | H | K | D | R | Q | Q | Y | W | N | A | L | P | L | E | K | A | G |
Template Known Secondary structure |   |
 |  |  |  |  |  |  | T | T |
| T | T | S |  |  |  | S | . | . | . | . | . | . |
|
| S |
|  |  |  |  |  |  |  |
| S |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  | T |
|
|  |  |  |
|
|
|
|
| T | T |
|  |  |  |  |  |  |  |  |  |  |  | T | T |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
227 | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | |
|
|
|
|
|
. | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 |
  |
  |   |
301 | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
K | A | R | V | I | R | L | I | T | G | Y | H | K | V | R | K | G | D | A | A | E | G | Y | H | Q | S | L | I | D | I | T | P | Q | R | V | L | E | E | L | N | A | L | L | L | Q | E |
Query Conservation |   |
  |   |   |   |
|   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |
|   |   |   |
|   |   |
|
|   |   |   |
Alig confidence |   |
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |
|   |   |   |   |   |
|
|   |
|
|   |   |
|   |   |   |   |
Template Sequence |   |
A | A | K | I | I | E | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Q | P | Q | L | S | V | D | A | V | A | N | T | L | A | G | W | S | R | E | T |
Template Known Secondary structure |   |
S |  |  |  |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | G | G | G |
|
|  |  |  |  |  |  |  |  |  | T |
|
|  |  |  |
Template Predicted Secondary structure |   |
|  |  |  |  |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
301 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . |
  |